Components of a Neanderthal gut microbiome recovered from fecal sediments from El Salt.


Journal

Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179

Informations de publication

Date de publication:
05 02 2021
Historique:
received: 19 04 2020
accepted: 05 01 2021
entrez: 6 2 2021
pubmed: 7 2 2021
medline: 18 8 2021
Statut: epublish

Résumé

A comprehensive view of our evolutionary history cannot ignore the ancestral features of our gut microbiota. To provide some glimpse into the past, we searched for human gut microbiome components in ancient DNA from 14 archeological sediments spanning four stratigraphic units of El Salt Middle Paleolithic site (Spain), including layers of unit X, which has yielded well-preserved Neanderthal occupation deposits dating around 50 kya. According to our findings, bacterial genera belonging to families known to be part of the modern human gut microbiome are abundantly represented only across unit X samples, showing that well-known beneficial gut commensals, such as Blautia, Dorea, Roseburia, Ruminococcus, Faecalibacterium and Bifidobacterium already populated the intestinal microbiome of Homo since as far back as the last common ancestor between humans and Neanderthals.

Identifiants

pubmed: 33547403
doi: 10.1038/s42003-021-01689-y
pii: 10.1038/s42003-021-01689-y
pmc: PMC7864912
doi:

Substances chimiques

DNA, Ancient 0

Types de publication

Historical Article Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

169

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM089886
Pays : United States

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Auteurs

Simone Rampelli (S)

Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, Bologna, Italy.

Silvia Turroni (S)

Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, Bologna, Italy.

Carolina Mallol (C)

Department of Geography and History, University of La Laguna, Campus de Guajara, La Laguna, Tenerife, Spain.
Archaeological Micromorphology and Biomarker Research Lab, University of La Laguna, Avenida Astrofísico Francisco Sánchez 2, La Laguna, Tenerife, Spain.
ICArEHB - Interdisciplinary Center for Archaeology and the Evolution of Human Behaviour, Universidade do Algarve, Campus de Gambelas, Edificio 1, Faro, Portugal.

Cristo Hernandez (C)

Department of Geography and History, University of La Laguna, Campus de Guajara, La Laguna, Tenerife, Spain.

Bertila Galván (B)

Department of Geography and History, University of La Laguna, Campus de Guajara, La Laguna, Tenerife, Spain.

Ainara Sistiaga (A)

Earth, Atmospheric and Planetary Sciences Department, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, MA, USA.
GLOBE Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Oester Voldgade 5-7, Copenhagen, Denmark.

Elena Biagi (E)

Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, Bologna, Italy.

Annalisa Astolfi (A)

"Giorgio Prodi" Cancer Research Center, University of Bologna, Via Massarenti 11, Bologna, Italy.
Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Via Fossato di Mortara 70, Ferrara, Italy.

Patrizia Brigidi (P)

Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, Bologna, Italy.

Stefano Benazzi (S)

Department of Cultural Heritage, University of Bologna, Via degli Ariani 1, Ravenna, Italy.
Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig, Germany.

Cecil M Lewis (CM)

Laboratories of Molecular Anthropology and Microbiome Research, University of Oklahoma, 101 David L. Boren Blvd, Norman, OK, USA.
Department of Anthropology, University of Oklahoma, 455W Lindsey St, Norman, OK, USA.

Christina Warinner (C)

Department of Anthropology, University of Oklahoma, 455W Lindsey St, Norman, OK, USA.
Department of Archaeogenetics, Max Planck Institute for the Science of Human History, Kahlaische Strasse 10, Jena, Germany.

Courtney A Hofman (CA)

Laboratories of Molecular Anthropology and Microbiome Research, University of Oklahoma, 101 David L. Boren Blvd, Norman, OK, USA.
Department of Anthropology, University of Oklahoma, 455W Lindsey St, Norman, OK, USA.

Stephanie L Schnorr (SL)

Konrad Lorenz Institute for Evolution and Cognition Research, Martinstraße 12, Klosterneuburg, Austria. stephanie.schnorr@kli.ac.at.
Department of Anthropology, University of Nevada, 4505S. Maryland Pkwy, Las Vegas, NV, USA. stephanie.schnorr@kli.ac.at.

Marco Candela (M)

Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, Bologna, Italy. marco.candela@unibo.it.

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