Effect of Posterior Tracheopexy on Risk of Recurrence in Children after Recurrent Tracheo-Esophageal Fistula Repair.


Journal

Journal of the American College of Surgeons
ISSN: 1879-1190
Titre abrégé: J Am Coll Surg
Pays: United States
ID NLM: 9431305

Informations de publication

Date de publication:
05 2021
Historique:
received: 16 12 2020
revised: 14 01 2021
accepted: 14 01 2021
pubmed: 9 2 2021
medline: 1 10 2021
entrez: 8 2 2021
Statut: ppublish

Résumé

A recurrent tracheo-esophageal fistula can complicate esophageal atresia and tracheo-esophageal fistula (TEF) repair in children. Therapeutic approaches and the rate of recurrence vary widely. Most reports are limited by small cohorts and short-term follow-up, and rates of re-recurrence are substantial, making it difficult to select the treatment of choice. We aimed to review our experience with the treatment of recurrent TEF using posterior tracheopexy, focusing on operative risks and long-term outcomes. We conducted a retrospective review of patients with esophageal atresia TEF with recurrent TEF treated at 2 institutions from 2011 to 2020. We approach recurrent TEFs surgically. Once the TEF is divided and repaired, the membranous trachea is sutured to the anterior longitudinal ligament of the spine (posterior tracheopexy) and the esophagus is rotated into the right chest (rotational esophagoplasty), separating the suture lines widely. To detect re-recurrence, patients undergo endoscopic surveillance during follow-up. Sixty-two patients with a recurrent TEF were surgically treated (posterior tracheopexy/rotational esophagoplasty) at a median age of 14 months. All had significant respiratory symptoms. On referral, 24 had earlier failed endoscopic and/or surgical attempts at repair. Twenty-nine required a concomitant esophageal anastomotic stricturoplasty or stricture resection. Postoperative morbidity included 3 esophageal leaks, and 1 transient vocal cord dysfunction. We have identified no recurrences, with a median follow-up of 2.5 years, and all symptoms have resolved. The surgical treatment of recurrent TEFs that incorporates a posterior tracheopexy and rotational esophagoplasty is highly effective for preventing re-recurrence with low perioperative morbidity.

Sections du résumé

BACKGROUND
A recurrent tracheo-esophageal fistula can complicate esophageal atresia and tracheo-esophageal fistula (TEF) repair in children. Therapeutic approaches and the rate of recurrence vary widely. Most reports are limited by small cohorts and short-term follow-up, and rates of re-recurrence are substantial, making it difficult to select the treatment of choice. We aimed to review our experience with the treatment of recurrent TEF using posterior tracheopexy, focusing on operative risks and long-term outcomes.
STUDY DESIGN
We conducted a retrospective review of patients with esophageal atresia TEF with recurrent TEF treated at 2 institutions from 2011 to 2020. We approach recurrent TEFs surgically. Once the TEF is divided and repaired, the membranous trachea is sutured to the anterior longitudinal ligament of the spine (posterior tracheopexy) and the esophagus is rotated into the right chest (rotational esophagoplasty), separating the suture lines widely. To detect re-recurrence, patients undergo endoscopic surveillance during follow-up.
RESULTS
Sixty-two patients with a recurrent TEF were surgically treated (posterior tracheopexy/rotational esophagoplasty) at a median age of 14 months. All had significant respiratory symptoms. On referral, 24 had earlier failed endoscopic and/or surgical attempts at repair. Twenty-nine required a concomitant esophageal anastomotic stricturoplasty or stricture resection. Postoperative morbidity included 3 esophageal leaks, and 1 transient vocal cord dysfunction. We have identified no recurrences, with a median follow-up of 2.5 years, and all symptoms have resolved.
CONCLUSIONS
The surgical treatment of recurrent TEFs that incorporates a posterior tracheopexy and rotational esophagoplasty is highly effective for preventing re-recurrence with low perioperative morbidity.

Identifiants

pubmed: 33556502
pii: S1072-7515(21)00099-5
doi: 10.1016/j.jamcollsurg.2021.01.011
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

690-698

Informations de copyright

Copyright © 2021 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Auteurs

Ali Kamran (A)

Departments of General Surgery, Boston Children's Hospital, Boston, MA.

Benjamin Zendejas (B)

Departments of General Surgery, Boston Children's Hospital, Boston, MA.

Jay Meisner (J)

Departments of General Surgery, Boston Children's Hospital, Boston, MA.

Sukgi S Choi (SS)

Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, MA.

Carlos Munoz-San Julian (C)

Anesthesiology, Perioperative, and Pain Medicine, Boston Children's Hospital, Boston, MA.

Peter Ngo (P)

Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA.

Michael Manfredi (M)

Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA.

Jessica L Yasuda (JL)

Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA.

C Jason Smithers (CJ)

Department of Surgery, Johns Hopkins All Children's Hospital, St Petersburg, FL.

Thomas E Hamilton (TE)

Departments of General Surgery, Boston Children's Hospital, Boston, MA.

Russell W Jennings (RW)

Departments of General Surgery, Boston Children's Hospital, Boston, MA. Electronic address: russell.jennings@childrens.harvard.edu.

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