The zebrafish


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
02 03 2021
Historique:
entrez: 18 2 2021
pubmed: 19 2 2021
medline: 5 8 2021
Statut: ppublish

Résumé

The establishment of cardiac function in the developing embryo is essential to ensure blood flow and, therefore, growth and survival of the animal. The molecular mechanisms controlling normal cardiac rhythm remain to be fully elucidated. From a forward genetic screen, we identified a unique mutant,

Identifiants

pubmed: 33597309
pii: 2018220118
doi: 10.1073/pnas.2018220118
pmc: PMC7936323
pii:
doi:

Substances chimiques

Membrane Proteins 0
Tmem161b protein, mouse 0
Tmem161b protein, zebrafish 0
Zebrafish Proteins 0
Potassium RWP5GA015D
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NHGRI NIH HHS
ID : U01 HG004080
Pays : United States
Organisme : NHGRI NIH HHS
ID : U01 HG004085
Pays : United States

Déclaration de conflit d'intérêts

The authors declare no competing interest.

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Auteurs

Charlotte D Koopman (CD)

Department of Cardiac Development and Genetics, Hubrecht Institute, University Medical Centre Utrecht, Utrecht 3584 CT, The Netherlands.
Department of Medical Physiology, Division of Heart & Lungs, University Medical Center, Utrecht 3584 CM, The Netherlands.

Jessica De Angelis (J)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.

Swati P Iyer (SP)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.

Arie O Verkerk (AO)

Department of Medical Biology, Amsterdam University Medical Centre, 1105 AZ Amsterdam, The Netherlands.

Jason Da Silva (J)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.

Geza Berecki (G)

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3010, Australia.
Department of the Florey Institute, The University of Melbourne, Parkville, VIC 3010, Australia.

Angela Jeanes (A)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.

Gregory J Baillie (GJ)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.

Scott Paterson (S)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.

Veronica Uribe (V)

Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.

Ophelia V Ehrlich (OV)

Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.

Samuel D Robinson (SD)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.

Laurence Garric (L)

Department of Cardiac Development and Genetics, Hubrecht Institute, University Medical Centre Utrecht, Utrecht 3584 CT, The Netherlands.

Steven Petrou (S)

The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC 3010, Australia.
Department of the Florey Institute, The University of Melbourne, Parkville, VIC 3010, Australia.

Cas Simons (C)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Genetics Theme, Murdoch Children's Research Institute, Parkville, VIC 3010, Australia.

Irina Vetter (I)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
School of Pharmacy, The University of Queensland, Brisbane, QLD 4102, Australia.

Benjamin M Hogan (BM)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Peter MacCallum Cancer Centre, The University of Melbourne, Parkville, VIC 3010, Australia.

Teun P de Boer (TP)

Department of Medical Physiology, Division of Heart & Lungs, University Medical Center, Utrecht 3584 CM, The Netherlands.

Jeroen Bakkers (J)

Department of Cardiac Development and Genetics, Hubrecht Institute, University Medical Centre Utrecht, Utrecht 3584 CT, The Netherlands.
Department of Medical Physiology, Division of Heart & Lungs, University Medical Center, Utrecht 3584 CM, The Netherlands.

Kelly A Smith (KA)

Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia; kelly.smith1@unimelb.edu.au.
Department of Physiology, The University of Melbourne, Parkville, VIC 3010, Australia.

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Classifications MeSH