15-Deoxy-△
Animals
Anti-Inflammatory Agents
/ pharmacology
Biomarkers
Colitis
/ drug therapy
Dextran Sulfate
/ adverse effects
Disease Models, Animal
Immunologic Factors
/ pharmacology
Intestinal Mucosa
/ immunology
Macrophages
/ drug effects
Male
Mice
Prostaglandin D2
/ analogs & derivatives
STAT3 Transcription Factor
Treatment Outcome
15-deoxy-△12,14-prostaglandin J2
DSS-induced colitis
STAT3
cyclopentenone prostaglandin
macrophage polarization
resolution of intestinal inflammation
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2021
2021
Historique:
received:
09
10
2020
accepted:
04
01
2021
entrez:
26
2
2021
pubmed:
27
2
2021
medline:
30
6
2021
Statut:
epublish
Résumé
Uncontrolled macrophage functions cause failure to resolve gut inflammation and has been implicated in the pathogenesis of inflammatory bowel disease (IBD). 15-Deoxy-Δ
Identifiants
pubmed: 33633749
doi: 10.3389/fimmu.2021.615803
pmc: PMC7901909
doi:
Substances chimiques
15-deoxy-delta(12,14)-prostaglandin J2
0
Anti-Inflammatory Agents
0
Biomarkers
0
Immunologic Factors
0
STAT3 Transcription Factor
0
Dextran Sulfate
9042-14-2
Prostaglandin D2
RXY07S6CZ2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
615803Informations de copyright
Copyright © 2021 Kim, Jang, Zhong, Seo and Surh.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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