MYELOLIPOMA COEXISTENCE WITH GLUCOCORTICOID AND ANDROGEN SECRETING ADRENOCORTICAL CARCINOMA: SLOW AND BENIGN CLINICAL COURSE.


Journal

Georgian medical news
ISSN: 1512-0112
Titre abrégé: Georgian Med News
Pays: Georgia (Republic)
ID NLM: 101218222

Informations de publication

Date de publication:
Jan 2021
Historique:
entrez: 4 3 2021
pubmed: 5 3 2021
medline: 6 3 2021
Statut: ppublish

Résumé

We present a case of androgen and glucocorticoid secreting adrenocortical carcinoma with concomitant myelolipoma. A giant adrenal tumor which was initially nonfunctional was reassessed four years later due to the patient's refusal to treat. The patient was a 48-year-old woman with hypertension and acne lesions on the face. Laboratory findings were consistent with glucocorticoid and androgen hypersecretion. Computed tomography revealed a heterogeneously contrasting mass of 145x118x100 mm with lobular contour and soft tissue areas. The patient underwent left laparoscopic transperitoneal adrenalectomy with three port technique. There were no complications in the perioperative period. The resected specimen weighed 850 grams. Pathological findings showed a combination of myelolipoma-adrenal cortical cancer. In the postoperative period, hypertension improved and the hormone panel was normalized. Postoperative computed tomography and PET-CT showed no residual mass and metastasis. Although imaging is compatible with benign masses such as myelolipoma, coexistence of ACC-myelolipoma should be kept in mind and functional evaluation should be performed.

Identifiants

pubmed: 33658401

Substances chimiques

Androgens 0
Glucocorticoids 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7-11

Auteurs

Taner Demirci (T)

Sakarya University, Medicine Faculty, Department of Internal Medicine, Division of Endocrinology; Sakarya University, Turkey.

Hasret Cengiz (H)

Sakarya University, Medicine Faculty, Department of Endocrinology; Sakarya University, Turkey.

Sedat Cetin (S)

Sakarya University, Medicine Faculty, Department of Internal Medicine, Division of Endocrinology; Sakarya University, Turkey.

Ceyhun Varim (C)

Sakarya University, Medicine Faculty, Department of Internal Medicine; Sakarya University, Turkey.

Gizem Karatas (G)

Sakarya University, Medicine Faculty, Department of Internal Medicine; Sakarya University, Turkey.

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Classifications MeSH