The Clinical Impact of Implementation of a Multidisciplinary Endocarditis Team.


Journal

The Annals of thoracic surgery
ISSN: 1552-6259
Titre abrégé: Ann Thorac Surg
Pays: Netherlands
ID NLM: 15030100R

Informations de publication

Date de publication:
Jan 2022
Historique:
received: 29 06 2020
revised: 10 02 2021
accepted: 16 02 2021
pubmed: 5 3 2021
medline: 22 1 2022
entrez: 4 3 2021
Statut: ppublish

Résumé

Infectious endocarditis is associated with substantial in-hospital mortality of 15%-20%. Effective management requires coordination between multiple medical and surgical subspecialties, which can often lead to disjointed care. Previous European studies have identified multidisciplinary endocarditis teams as a tool for reducing endocarditis mortality. The multidisciplinary endocarditis team was formed in May 2018. The group developed an evidence-based algorithm for management of endocarditis that was used to provide recommendations for hospitalized patients over a 1-year period. Mortality outcomes were then retroactively assessed and compared to a historical control utilizing propensity matching. Between June 2018 and June 2019 the team provided guideline-based recommendations on 56 patients with Duke Criteria-definite endocarditis and at least 1 American Heart Association indication for surgery. The historical control included 68 patients with definite endocarditis and surgical indications admitted between July 1, 2014, and June 30, 2015. In-hospital mortality decreased significantly from 29.4% in 2014-2015 to 7.1% in 2018-2019 (P < .0001). There was a non-significant increase in the rate of surgical intervention after implementation of the team (41.2% vs 55.4%; P = 0.12). Propensity score matching demonstrated similar results. Implementation of a multidisciplinary endocarditis team was associated with a significant 1-year decrease in all-cause in-hospital mortality for patients with definite endocarditis and surgical indications, in the presence of notable differences between the 2 studied cohorts. In conjunction with previous studies demonstrating their effectiveness, these data support the idea that widespread adoption of endocarditis teams in North America could improve outcomes for this patient population.

Sections du résumé

BACKGROUND BACKGROUND
Infectious endocarditis is associated with substantial in-hospital mortality of 15%-20%. Effective management requires coordination between multiple medical and surgical subspecialties, which can often lead to disjointed care. Previous European studies have identified multidisciplinary endocarditis teams as a tool for reducing endocarditis mortality.
METHODS METHODS
The multidisciplinary endocarditis team was formed in May 2018. The group developed an evidence-based algorithm for management of endocarditis that was used to provide recommendations for hospitalized patients over a 1-year period. Mortality outcomes were then retroactively assessed and compared to a historical control utilizing propensity matching.
RESULTS RESULTS
Between June 2018 and June 2019 the team provided guideline-based recommendations on 56 patients with Duke Criteria-definite endocarditis and at least 1 American Heart Association indication for surgery. The historical control included 68 patients with definite endocarditis and surgical indications admitted between July 1, 2014, and June 30, 2015. In-hospital mortality decreased significantly from 29.4% in 2014-2015 to 7.1% in 2018-2019 (P < .0001). There was a non-significant increase in the rate of surgical intervention after implementation of the team (41.2% vs 55.4%; P = 0.12). Propensity score matching demonstrated similar results.
CONCLUSIONS CONCLUSIONS
Implementation of a multidisciplinary endocarditis team was associated with a significant 1-year decrease in all-cause in-hospital mortality for patients with definite endocarditis and surgical indications, in the presence of notable differences between the 2 studied cohorts. In conjunction with previous studies demonstrating their effectiveness, these data support the idea that widespread adoption of endocarditis teams in North America could improve outcomes for this patient population.

Identifiants

pubmed: 33662308
pii: S0003-4975(21)00346-5
doi: 10.1016/j.athoracsur.2021.02.027
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

118-124

Informations de copyright

Copyright © 2022 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Auteurs

Sami El-Dalati (S)

Department of Internal Medicine, Division of Infectious Diseases, Michigan Medicine - University of Michigan, Ann Arbor, Michigan. Electronic address: seldalat@med.umich.edu.

Daniel Cronin (D)

Department of Internal Medicine, Division of Hospital Medicine, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

James Riddell (J)

Department of Internal Medicine, Division of Infectious Diseases, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Michael Shea (M)

Department of Internal Medicine, Division of Cardiology, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Richard L Weinberg (RL)

Department of Internal Medicine, Division of Cardiology, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Laraine Washer (L)

Department of Internal Medicine, Division of Infectious Diseases, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Emily Stoneman (E)

Department of Internal Medicine, Division of Infectious Diseases, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

D Alexander Perry (DA)

Department of Internal Medicine, Division of Infectious Diseases, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Suzanne Bradley (S)

Department of Internal Medicine, Division of Infectious Diseases, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

James Burke (J)

Department of Neurology, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Sadhana Murali (S)

Department of Neurology, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Christopher Fagan (C)

Department of Internal Medicine, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Rishi Chanderraj (R)

Department of Internal Medicine, Division of Infectious Diseases, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Paul Christine (P)

Department of Internal Medicine, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Twisha Patel (T)

College of Pharmacy, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Kirra Ressler (K)

Department of Cardiac Surgery, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Shinichi Fukuhara (S)

Department of Cardiac Surgery, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Matthew Romano (M)

Department of Cardiac Surgery, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

Bo Yang (B)

Department of Cardiac Surgery, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

George Michael Deeb (GM)

Department of Cardiac Surgery, Michigan Medicine - University of Michigan, Ann Arbor, Michigan.

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