Cyanophora paradoxa mitochondrial tRNAs play a double game.


Journal

The Plant journal : for cell and molecular biology
ISSN: 1365-313X
Titre abrégé: Plant J
Pays: England
ID NLM: 9207397

Informations de publication

Date de publication:
05 2021
Historique:
revised: 26 02 2021
received: 08 01 2021
accepted: 01 03 2021
pubmed: 6 3 2021
medline: 15 12 2021
entrez: 5 3 2021
Statut: ppublish

Résumé

Present-day mitochondria derive from a single endosymbiosis of an α-proteobacterium into a proto-eukaryotic cell. Since this monophyletic event, mitochondria have evolved considerably, and unique traits have been independently acquired in the different eukaryotic kingdoms. Mitochondrial genome expression and RNA metabolism have diverged greatly. Here, Cyanophora paradoxa, a freshwater alga considered as a living fossil among photosynthetic organisms, represents an exciting model for studying the evolution of mitochondrial gene expression. As expected, fully mature tRNAs are released from primary transcripts to function in mitochondrial translation. We also show that these tRNAs take part in an mRNA processing punctuation mechanism in a non-conventional manner, leading to mRNA-tRNA hybrids with a CCA triplet at their 3'-extremities. In this case, tRNAs are probably used as stabilizing structures impeding the degradation of mRNA by exonucleases. From our data we propose that the present-day tRNA-like elements (t-elements) found at the 3'-terminals of mitochondrial mRNAs in land plants originate from true tRNAs like those observed in the mitochondria of this basal photosynthetic glaucophyte.

Identifiants

pubmed: 33666295
doi: 10.1111/tpj.15222
doi:

Substances chimiques

RNA, Messenger 0
RNA, Mitochondrial 0
mitochondrial messenger RNA 0
RNA, Transfer 9014-25-9

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1105-1115

Informations de copyright

© 2021 Society for Experimental Biology and John Wiley & Sons Ltd.

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Auteurs

Thalia Salinas-Giegé (T)

Institut de Biologie Moléculaire des Plantes-CNRS, Université de Strasbourg, Strasbourg, France.

Elodie Ubrig (E)

Institut de Biologie Moléculaire des Plantes-CNRS, Université de Strasbourg, Strasbourg, France.

Laurence Drouard (L)

Institut de Biologie Moléculaire des Plantes-CNRS, Université de Strasbourg, Strasbourg, France.

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