Relative decrease in hemoglobin and outcomes in patients undergoing kidney transplantation surgery: A retrospective cohort study.
Anemia
Blood transfusion
Hemoglobin
Kidney transplantation
Transplant outcomes
Journal
American journal of surgery
ISSN: 1879-1883
Titre abrégé: Am J Surg
Pays: United States
ID NLM: 0370473
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
26
10
2020
revised:
09
02
2021
accepted:
01
03
2021
pubmed:
13
3
2021
medline:
7
10
2021
entrez:
12
3
2021
Statut:
ppublish
Résumé
Recent surgical literature suggests that a relative decrease in hemoglobin (ΔHb) is predictive of adverse outcomes regardless of the absolute level. We aimed to examine the association between perioperative ΔHb and kidney transplantation (KT) outcomes. This was a retrospective cohort study of transplant recipients, where ΔHb = [Hb0- Hb1Hb0]x 100 (Hb Of the 899 eligible patients, 38% experienced IGF, and ΔHb was associated with 36% lower odds of IGF. Also, ΔHb was associated with higher all-cause graft failure and longer length of stay but not death-censored graft failure or mortality. ΔHb ≥30% was the threshold beyond which the odds of IGF were significantly lower even if Hb ΔHb is associated with inferior outcomes independent of Hb
Sections du résumé
BACKGROUND
BACKGROUND
Recent surgical literature suggests that a relative decrease in hemoglobin (ΔHb) is predictive of adverse outcomes regardless of the absolute level. We aimed to examine the association between perioperative ΔHb and kidney transplantation (KT) outcomes.
METHODS
METHODS
This was a retrospective cohort study of transplant recipients, where ΔHb = [Hb0- Hb1Hb0]x 100 (Hb
RESULTS
RESULTS
Of the 899 eligible patients, 38% experienced IGF, and ΔHb was associated with 36% lower odds of IGF. Also, ΔHb was associated with higher all-cause graft failure and longer length of stay but not death-censored graft failure or mortality. ΔHb ≥30% was the threshold beyond which the odds of IGF were significantly lower even if Hb
CONCLUSION
CONCLUSIONS
ΔHb is associated with inferior outcomes independent of Hb
Identifiants
pubmed: 33707078
pii: S0002-9610(21)00116-1
doi: 10.1016/j.amjsurg.2021.03.002
pii:
doi:
Substances chimiques
Hemoglobins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
825-831Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest Dr. Sandal has received an education grant from Amgen to increase living donor kidney transplantation. In the past five years, Dr Chaudhury discloses Ad board and honoraria from Ipsen and Novartis Oncology. Dr. Tchervenkov discloses that he has received a PI initiated Astellas/Canadian Society of Transplantation Research Support that ended in 2018. The other authors have no relevant disclosures.