Genetic Determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response

Acrylamides / pharmacology Adenocarcinoma of Lung / drug therapy Aniline Compounds / pharmacology Animals Antineoplastic Agents / pharmacology Disease Models, Animal ErbB Receptors / genetics Female Humans Lung Neoplasms / drug therapy Male Mice

Journal

Cancer discovery
ISSN: 2159-8290
Titre abrégé: Cancer Discov
Pays: United States
ID NLM: 101561693

Informations de publication

Date de publication:
07 2021
Historique:
received: 25 09 2020
revised: 23 12 2020
accepted: 11 02 2021
pubmed: 13 3 2021
medline: 1 3 2022
entrez: 12 3 2021
Statut: ppublish

Résumé

In lung adenocarcinoma, oncogenic

Identifiants

DOI: 10.1158/2159-8290.CD-20-1385 PMID: 33707235 PMC: PMC8530463
pubmed: 33707235
pii: 2159-8290.CD-20-1385
doi: 10.1158/2159-8290.CD-20-1385
pmc: PMC8530463
mid: NIHMS1684781
doi:

Substances chimiques

Acrylamides 0
Aniline Compounds 0
Antineoplastic Agents 0
osimertinib 3C06JJ0Z2O
ErbB Receptors EC 2.7.10.1

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1736-1753

Subventions

Organisme : NCI NIH HHS
ID : F31 CA203488
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA120247
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM118165
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA234349
Pays : United States
Organisme : NCI NIH HHS
ID : F32 CA210516
Pays : United States
Organisme : NCI NIH HHS
ID : P50 CA196530
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA231253
Pays : United States

Informations de copyright

©2021 American Association for Cancer Research.

Références

Nature. 2014 Dec 18;516(7531):428-31
pubmed: 25337879
Nature. 2007 Aug 16;448(7155):807-10
pubmed: 17676035
Nucleic Acids Res. 2010 Sep;38(16):e164
pubmed: 20601685
Nat Methods. 2018 Apr;15(4):271-274
pubmed: 29457792
Cancer Res. 2002 Jan 15;62(2):371-5
pubmed: 11809682
Clin Cancer Res. 2013 Aug 1;19(15):4273-81
pubmed: 23729361
Cell. 2015 Mar 12;160(6):1246-60
pubmed: 25748654
Elife. 2015 Jun 05;4:e06907
pubmed: 26047463
Cancer Res. 2020 May 15;80(10):2017-2030
pubmed: 32193290
Nat Rev Genet. 2018 Dec;19(12):741-755
pubmed: 30267031
Nat Med. 2017 Nov;23(11):1362-1368
pubmed: 28967920
Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19096-101
pubmed: 19861545
Cancer Res. 2021 Sep 1;81(17):4570-4580
pubmed: 34215621
J Thorac Oncol. 2019 Oct;14(10):1784-1793
pubmed: 31228622
Nat Methods. 2017 Jul;14(7):737-742
pubmed: 28530655
Cell. 2011 Mar 4;144(5):646-74
pubmed: 21376230
Cancer Res. 2007 Jul 1;67(13):6007-11
pubmed: 17616654
Cell. 2018 Apr 5;173(2):371-385.e18
pubmed: 29625053
Mol Cancer Res. 2014 Jun;12(6):912-23
pubmed: 24618618
Cancer Discov. 2017 Aug;7(8):818-831
pubmed: 28572459
Cell. 2019 May 30;177(6):1375-1383
pubmed: 31150618
Nat Neurosci. 2010 Jan;13(1):133-40
pubmed: 20023653
N Engl J Med. 2017 Jun 1;376(22):2109-2121
pubmed: 28445112
Mod Pathol. 1999 Mar;12(3):318-24
pubmed: 10102618
Nat Genet. 2001 Dec;29(4):418-25
pubmed: 11694875
PLoS One. 2009;4(5):e5475
pubmed: 19421407
Nucleic Acids Res. 2003 Oct 1;31(19):5582-9
pubmed: 14500821
Nat Commun. 2019 Nov 6;10(1):5043
pubmed: 31695040
Nature. 2014 Jul 31;511(7511):543-50
pubmed: 25079552
Cancer Discov. 2014 Jul;4(7):781-9
pubmed: 24740995
Nat Med. 2017 Jun;23(6):703-713
pubmed: 28481359
Nat Rev Cancer. 2019 Sep;19(9):495-509
pubmed: 31406302
N Engl J Med. 2018 Jan 11;378(2):113-125
pubmed: 29151359
J Clin Oncol. 2018 Mar 20;36(9):841-849
pubmed: 28841389
Insight J. 2006;2006:209
pubmed: 25364771
Nat Genet. 2016 Jun;48(6):607-16
pubmed: 27158780
Cancer Discov. 2020 Dec;10(12):1826-1841
pubmed: 33071215
Clin Cancer Res. 2018 Jul 1;24(13):3108-3118
pubmed: 29530932
RNA Biol. 2016;13(4):466-72
pubmed: 26853560
Proc Natl Acad Sci U S A. 2004 Sep 7;101(36):13306-11
pubmed: 15329413
Clin Cancer Res. 2018 Jan 15;24(2):334-340
pubmed: 29089357
Nat Protoc. 2009;4(7):1064-72
pubmed: 19561589
Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):E6409-E6417
pubmed: 27702896
Sci Rep. 2017 Jan 16;7:40488
pubmed: 28091594
N Engl J Med. 2020 Jan 2;382(1):41-50
pubmed: 31751012
Nat Genet. 2015 Dec;47(12):1475-81
pubmed: 26482881
Nature. 2019 May;569(7756):423-427
pubmed: 31043741
Lung Cancer. 2019 Aug;134:42-45
pubmed: 31319993
Clin Cancer Res. 2016 Jan 15;22(2):426-35
pubmed: 26341921
Cell Rep. 2019 Jun 18;27(12):3422-3432.e4
pubmed: 31216465
Cancer Res. 2014 Oct 15;74(20):5891-902
pubmed: 25164010
Oncogene. 2017 Sep 14;36(37):5321-5330
pubmed: 28534518
Science. 2004 Jun 4;304(5676):1497-500
pubmed: 15118125
Cancer Discov. 2017 Jun;7(6):596-609
pubmed: 28336552
Nat Commun. 2017 Dec 12;8(1):2053
pubmed: 29233960
Cell Rep. 2014 May 22;7(4):999-1008
pubmed: 24813888
Cancer Res. 2019 Jul 1;79(13):3251-3267
pubmed: 31040157
Cell. 2014 Oct 9;159(2):440-55
pubmed: 25263330
Clin Cancer Res. 2020 Jun 1;26(11):2654-2663
pubmed: 31911548
Cancer Discov. 2015 Aug;5(8):860-77
pubmed: 26069186
PLoS One. 2014 Jun 04;9(6):e98896
pubmed: 24896564
J Biol Chem. 2010 Jul 16;285(29):22576-91
pubmed: 20452972
Cancer Res. 2017 Jun 1;77(11):3040-3056
pubmed: 28363999
Sci Transl Med. 2011 Mar 23;3(75):75ra26
pubmed: 21430269
Nature. 2010 Dec 2;468(7324):653-8
pubmed: 21124450
PLoS One. 2014 Apr 17;9(4):e95236
pubmed: 24743474
J Thorac Oncol. 2019 Apr;14(4):606-616
pubmed: 30605727
Nature. 2013 Aug 22;500(7463):415-21
pubmed: 23945592
Clin Cancer Res. 2015 May 15;21(10):2213-20
pubmed: 25979927
Genes Dev. 2001 Dec 15;15(24):3243-8
pubmed: 11751630
Nat Genet. 2018 Apr;50(4):483-486
pubmed: 29610476
N Engl J Med. 2006 Jul 13;355(2):213-5
pubmed: 16837691
Antioxidants (Basel). 2020 Sep 22;9(9):
pubmed: 32971994
N Engl J Med. 2004 May 20;350(21):2129-39
pubmed: 15118073
Hum Pathol. 2003 Jun;34(6):597-604
pubmed: 12827614
Nat Genet. 2017 Dec;49(12):1693-1704
pubmed: 29106415
Elife. 2017 Oct 31;6:
pubmed: 29087937
Nat Cancer. 2020 Jun;1(6):589-602
pubmed: 34414377
Oncogene. 2009 Mar 12;28(10):1393-9
pubmed: 19151761
Genes Dev. 2016 Jun 15;30(12):1470-80
pubmed: 27340177
EMBO Mol Med. 2017 Feb;9(2):137-153
pubmed: 28028012
Nat Med. 2017 Mar;23(3):291-300
pubmed: 28191885
Oncogene. 2012 Nov 8;31(45):4768-77
pubmed: 22249257
Cell Rep. 2014 Jun 26;7(6):2078-86
pubmed: 24931605
Nat Rev Genet. 2014 Sep;15(9):585-98
pubmed: 24981601
FASEB J. 2018 May 29;:fj201800011R
pubmed: 29812969
Oncogene. 2001 Jun 14;20(27):3528-32
pubmed: 11429699
Cell. 2018 Apr 5;173(2):321-337.e10
pubmed: 29625050
Genes Dev. 2006 Jun 1;20(11):1496-510
pubmed: 16705038
Mol Cell. 2013 Dec 12;52(5):720-33
pubmed: 24332178
Cancer Cell. 2011 Jan 18;19(1):72-85
pubmed: 21251614
Cancer Res. 2017 Apr 1;77(7):1719-1729
pubmed: 28202515

Auteurs

Giorgia Foggetti (G)

Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.
ORCID: 0000-0003-1844-1413

Chuan Li (C)

Department of Biology, Stanford University, Stanford, California.
ORCID: 0000-0002-4381-3891

Hongchen Cai (H)

Department of Genetics, Stanford University School of Medicine, Stanford, California.

Jessica A Hellyer (JA)

Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California.

Wen-Yang Lin (WY)

Department of Genetics, Stanford University School of Medicine, Stanford, California.

Deborah Ayeni (D)

Department of Pathology, Yale School of Medicine, New Haven, Connecticut.

Katherine Hastings (K)

Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.

Jungmin Choi (J)

Department of Genetics, Yale School of Medicine, New Haven, Connecticut.
Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Korea.

Anna Wurtz (A)

Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.

Laura Andrejka (L)

Department of Genetics, Stanford University School of Medicine, Stanford, California.
ORCID: 0000-0002-2202-5626

Dylan G Maghini (DG)

Department of Genetics, Stanford University School of Medicine, Stanford, California.
ORCID: 0000-0001-9542-492X

Nicholas Rashleigh (N)

Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.

Stellar Levy (S)

Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.

Robert Homer (R)

Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.
Department of Pathology, Yale School of Medicine, New Haven, Connecticut.
VA Connecticut Healthcare System, Pathology and Laboratory Medicine Service, West Haven, Connecticut.
ORCID: 0000-0002-2055-5885

Scott N Gettinger (SN)

Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut.
Section of Medical Oncology, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.

Maximilian Diehn (M)

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California.
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
ORCID: 0000-0003-2032-0581

Heather A Wakelee (HA)

Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California.
Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
ORCID: 0000-0003-1136-980X

Dmitri A Petrov (DA)

Department of Biology, Stanford University, Stanford, California.
ORCID: 0000-0002-3664-9130

Monte M Winslow (MM)

Department of Genetics, Stanford University School of Medicine, Stanford, California. katerina.politi@yale.edu mwinslow@stanford.edu.
Division of Oncology, Department of Medicine, Stanford University School of Medicine, Stanford, California.
Department of Pathology, Stanford University School of Medicine, Stanford, California.

Katerina Politi (K)

Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut. katerina.politi@yale.edu mwinslow@stanford.edu.
Department of Pathology, Yale School of Medicine, New Haven, Connecticut.
Section of Medical Oncology, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Acrylates › Acrylamides › Genetic Determinants of EGFR-Driven Lung...
questionsmedicales.fr › Tumeurs › Tumeurs par siège › Tumeurs du thorax › Adénocarcinome pulmonaire › Genetic Determinants of EGFR-Driven Lung...
questionsmedicales.fr › Composés chimiques organiques › Amines › Dérivés de l'aniline › Genetic Determinants of EGFR-Driven Lung...
questionsmedicales.fr › Eucaryotes › Animaux › Genetic Determinants of EGFR-Driven Lung...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Genetic Determinants of EGFR-Driven Lung...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Genetic Determinants of EGFR-Driven Lung...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteur facteur croissance › Récepteurs ErbB › Genetic Determinants of EGFR-Driven Lung...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Genetic Determinants of EGFR-Driven Lung...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Tumeurs de l'appareil respiratoire › Tumeurs du poumon › Genetic Determinants of EGFR-Driven Lung...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Genetic Determinants of EGFR-Driven Lung...