The link between hidradenitis suppurativa and phylloid hypomelanosis in partial trisomy-13 mosaicism: New evidences and further genetic/pathogenetic insights.
Patau syndrome
hidradenitis suppurativa
hypopigmentation
partial trisomy-13 mosaicism
phylloid hypomelanosis
Journal
Pediatric dermatology
ISSN: 1525-1470
Titre abrégé: Pediatr Dermatol
Pays: United States
ID NLM: 8406799
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
revised:
15
01
2021
received:
27
08
2020
accepted:
24
01
2021
pubmed:
15
3
2021
medline:
8
7
2021
entrez:
14
3
2021
Statut:
ppublish
Résumé
Partial trisomy-13 mosaicism (PT13M) is a rare condition. Among its possible associated cutaneous features, phylloid hypomelanosis (PH), characterized by leaf-like macules reminiscent of floral ornaments in the form of round or oval spots and patches and oblong lesions, is typical. Two cases of PH associated with hidradenitis suppurativa (HS) have been already reported in the literature. We report a third child with PH due to PT13M associated with HS-like lesions limited to hypomelanotic regions. We hypothesize that follicular occlusion genes may be located in the duplicated part of chromosome 13.
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
637-639Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
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