Activation of the β-carbonic anhydrase from the protozoan pathogen

Amines / chemistry Amino Acids / chemistry Carbonic Anhydrases / metabolism Dose-Response Relationship, Drug Molecular Structure Structure-Activity Relationship Trichomonas vaginalis / enzymology
Amine Trichomonas vaginalis activator amino acid carbonic anhydrase

Journal

Journal of enzyme inhibition and medicinal chemistry
ISSN: 1475-6374
Titre abrégé: J Enzyme Inhib Med Chem
Pays: England
ID NLM: 101150203

Informations de publication

Date de publication:
Dec 2021
Historique:
entrez: 15 3 2021
pubmed: 16 3 2021
medline: 7 7 2021
Statut: ppublish

Résumé

We report the first activation study of the β-class carbonic anhydrase (CA, EC 4.2.1.1) encoded in the genome of the protozoan pathogen

Identifiants

DOI: 10.1080/14756366.2021.1897802 PMID: 33715570 PMC: PMC7952076
pubmed: 33715570
doi: 10.1080/14756366.2021.1897802
pmc: PMC7952076
doi:

Substances chimiques

Amines 0
Amino Acids 0
Carbonic Anhydrases EC 4.2.1.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

758-763

Références

EMBO J. 2000 Apr 3;19(7):1407-18
pubmed: 10747009
Int J Antimicrob Agents. 2019 Feb;53(2):116-127
pubmed: 30612993
Nat Rev Drug Discov. 2008 Feb;7(2):168-81
pubmed: 18167490
Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):16000-16008
pubmed: 32571910
J Enzyme Inhib Med Chem. 2018 Dec;33(1):139-146
pubmed: 29192555
Metabolites. 2019 Feb 01;9(2):
pubmed: 30717275
J Enzyme Inhib Med Chem. 2012 Dec;27(6):759-72
pubmed: 22468747
Expert Opin Drug Discov. 2017 Jan;12(1):61-88
pubmed: 27783541
J Enzyme Inhib Med Chem. 2018 Dec;33(1):680-685
pubmed: 29536765
J Enzyme Inhib Med Chem. 2020 Dec;35(1):1379-1386
pubmed: 32576029
Curr Infect Dis Rep. 2019 Aug 6;21(9):31
pubmed: 31388764
Cell Calcium. 2019 Dec;84:102080
pubmed: 31589941
Mar Drugs. 2019 Apr 22;17(4):
pubmed: 31013612
J Enzyme Inhib Med Chem. 2019 Dec;34(1):644-650
pubmed: 30727781
J Enzyme Inhib Med Chem. 2020 Dec;35(1):1292-1299
pubmed: 32515610
J Enzyme Inhib Med Chem. 2019 Dec;34(1):1100-1109
pubmed: 31124384
J Enzyme Inhib Med Chem. 2018 Dec;33(1):25-30
pubmed: 29098887
J Enzyme Inhib Med Chem. 2019 Dec;34(1):1652-1659
pubmed: 31530034
Bioorg Chem. 2018 Oct;80:261-265
pubmed: 29966872
Anal Chem. 2020 Mar 17;92(6):4614-4622
pubmed: 32096628
Chem Rev. 2012 Aug 8;112(8):4421-68
pubmed: 22607219
Bioorg Med Chem Lett. 2017 Jan 1;27(1):77-80
pubmed: 27881231
N Engl J Med. 2014 Jul 31;371(5):397-9
pubmed: 25075832
Expert Opin Drug Discov. 2020 Feb;15(2):145-158
pubmed: 31670987
Bioorg Chem. 2018 Oct;80:94-98
pubmed: 29894892
Biochem J. 2016 Jul 15;473(14):2023-32
pubmed: 27407171
J Enzyme Inhib Med Chem. 2018 Dec;33(1):364-369
pubmed: 29322836
J Enzyme Inhib Med Chem. 2021 Dec;36(1):329-334
pubmed: 33356653
Acta Crystallogr D Struct Biol. 2020 Jul 1;76(Pt 7):676-686
pubmed: 32627740
J Med Chem. 2013 Sep 26;56(18):7372-81
pubmed: 23977960
Chemistry. 2006 Sep 18;12(27):7057-66
pubmed: 16807956
J Enzyme Inhib Med Chem. 2020 Dec;35(1):1545-1554
pubmed: 32746656
Biochemistry. 1997 Aug 26;36(34):10384-92
pubmed: 9265618
Expert Opin Drug Discov. 2019 Nov;14(11):1175-1197
pubmed: 31436118
J Inorg Biochem. 2020 Dec;213:111274
pubmed: 33068968
Int J Mol Sci. 2020 Jun 11;21(11):
pubmed: 32545297
Future Med Chem. 2018 Mar 1;10(5):561-573
pubmed: 29478330
Nat Rev Drug Discov. 2011 Sep 16;10(10):767-77
pubmed: 21921921
Expert Opin Ther Targets. 2015;19(12):1689-704
pubmed: 26235676
J Enzyme Inhib Med Chem. 2019 Dec;34(1):1186-1192
pubmed: 31282228
ACS Cent Sci. 2019 Feb 27;5(2):308-318
pubmed: 30834319
Expert Opin Ther Pat. 2020 Dec;30(12):963-982
pubmed: 32806966
J Enzyme Inhib Med Chem. 2020 Dec;35(1):1060-1068
pubmed: 32314608
Curr Pharm Des. 2008;14(7):631-40
pubmed: 18336308
Metabolites. 2018 Mar 21;8(2):
pubmed: 29561812
Expert Opin Drug Discov. 2020 Jun;15(6):671-686
pubmed: 32208982
J Biol Chem. 1971 Apr 25;246(8):2561-73
pubmed: 4994926
J Enzyme Inhib Med Chem. 2018 Dec;33(1):850-857
pubmed: 29708476
J Enzyme Inhib Med Chem. 2020 Dec;35(1):1206-1214
pubmed: 32401069
Molecules. 2020 May 12;25(10):
pubmed: 32408533
J Enzyme Inhib Med Chem. 2018 Dec;33(1):286-289
pubmed: 29278948
J Biol Chem. 2006 Feb 24;281(8):4993-9
pubmed: 16321983
J Enzyme Inhib Med Chem. 2019 Dec;34(1):1164-1171
pubmed: 31219348
J Med Chem. 2020 Apr 23;63(8):4306-4314
pubmed: 32223141
Curr Med Chem. 2018;25(39):5266-5278
pubmed: 29589529
J Enzyme Inhib Med Chem. 2016;31(3):345-60
pubmed: 26619898
J Med Chem. 2013 Feb 28;56(4):1761-71
pubmed: 23391336
Bioorg Med Chem. 2017 Mar 1;25(5):1543-1555
pubmed: 28161253
Med Res Rev. 2020 Nov;40(6):2485-2565
pubmed: 32691504
J Med Chem. 2006 May 18;49(10):3019-27
pubmed: 16686544
Bioorg Chem. 2018 Aug;78:406-410
pubmed: 29689418

Auteurs

Andrea Angeli (A)

Neurofarba Department, Sezione di Chimica Farmaceutica e Nutraceutica, Università degli Studi di Firenze, Firenze, Italy.
ORCID: 0000-0002-1470-7192

Linda J Urbański (LJ)

Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.

Vesa P Hytönen (VP)

Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Fimlab Ltd, Tampere, Finland.

Seppo Parkkila (S)

Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Fimlab Ltd, Tampere, Finland.
ORCID: 0000-0001-7323-8536

Claudiu T Supuran (CT)

Neurofarba Department, Sezione di Chimica Farmaceutica e Nutraceutica, Università degli Studi di Firenze, Firenze, Italy.
ORCID: 0000-0003-4262-0323

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Amines › Activation of the β-carbonic anhydrase from...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Activation of the β-carbonic anhydrase from...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Lyases › Carbon-oxygen lyases › Hydro-lyases › Carbonic anhydrases › Activation of the β-carbonic anhydrase from...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Activation of the β-carbonic anhydrase from...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Activation of the β-carbonic anhydrase from...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Activation of the β-carbonic anhydrase from...
questionsmedicales.fr › Eucaryotes › Parabasalidea › Trichomonadida › Trichomonas › Trichomonas vaginalis › Activation of the β-carbonic anhydrase from...