Reduced-iodine-dose dual-energy coronary CT angiography: qualitative and quantitative comparison between virtual monochromatic and polychromatic CT images.
Adult
Aged
Computed Tomography Angiography
Contrast Media
Dose-Response Relationship, Drug
Humans
Iodine
/ administration & dosage
Middle Aged
Radiographic Image Interpretation, Computer-Assisted
Radiography, Dual-Energy Scanned Projection
Retrospective Studies
Signal-To-Noise Ratio
Tomography, X-Ray Computed
Computed tomography angiography
Coronary vessels
Dimensional measurement accuracy
Iodine
Phantoms, imaging
Journal
European radiology
ISSN: 1432-1084
Titre abrégé: Eur Radiol
Pays: Germany
ID NLM: 9114774
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
01
10
2020
accepted:
17
02
2021
revised:
06
01
2021
pubmed:
20
3
2021
medline:
25
8
2021
entrez:
19
3
2021
Statut:
ppublish
Résumé
To quantitatively evaluate the impact of virtual monochromatic images (VMI) on reduced-iodine-dose dual-energy coronary computed tomography angiography (CCTA) in terms of coronary lumen segmentation in vitro, and secondly to assess the image quality in vivo, compared with conventional CT obtained with regular iodine dose. A phantom simulating regular and reduced iodine injection was used to determine the accuracy and precision of lumen area segmentation for various VMI energy levels. We retrospectively included 203 patients from December 2017 to August 2018 (mean age, 51.7 ± 16.8 years) who underwent CCTA using either standard (group A, n = 103) or reduced (group B, n = 100) iodine doses. Conventional images (group A) were qualitatively and quantitatively compared with 55-keV VMI (group B). We recorded the location of venous catheters. In vitro, VMI outperformed conventional CT, with a segmentation accuracy of 0.998 vs. 1.684 mm In vitro, low-keV VMI improve vessel area segmentation. In vivo, low-keV VMI allows for a 40% iodine dose and injection rate reduction while maintaining diagnostic image quality and improves the CNR between lumen versus fat and muscle. • Dual-energy coronary CT angiography is becoming increasingly available and might help improve patient management. • Compared with regular-iodine-dose coronary CT angiography, reduced-iodine-dose dual-energy CT with low-keV monochromatic image reconstructions performed better in phantom-based vessel cross-sectional segmentation and proved to be noninferior in vivo. • Patients receiving reduced-iodine-dose dual-energy coronary CT angiography often had the venous catheter placed on the forearm or wrist without compromising image quality.
Identifiants
pubmed: 33740093
doi: 10.1007/s00330-021-07809-w
pii: 10.1007/s00330-021-07809-w
pmc: PMC8379124
doi:
Substances chimiques
Contrast Media
0
Iodine
9679TC07X4
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
7132-7142Informations de copyright
© 2021. The Author(s).
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