Neonatal surgical outcomes: a prospective observational study at a Tertiary Academic Hospital in Johannesburg, South Africa.
Enterocolitis, Necrotizing
/ mortality
Female
Gastroschisis
/ mortality
Gestational Age
Humans
Infant
Infant, Newborn
Intensive Care Units, Neonatal
Male
Neonatal Sepsis
/ mortality
Postoperative Complications
/ mortality
Prospective Studies
South Africa
/ epidemiology
Tertiary Care Centers
/ statistics & numerical data
Neonatal outcomes
Neonatal surgery
South Africa
Surgical outcomes
Journal
Pediatric surgery international
ISSN: 1437-9813
Titre abrégé: Pediatr Surg Int
Pays: Germany
ID NLM: 8609169
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
accepted:
02
03
2021
pubmed:
20
3
2021
medline:
10
7
2021
entrez:
19
3
2021
Statut:
ppublish
Résumé
The neonatal period is the most vulnerable period for a child. There is a paucity of data on the burden of neonatal surgical disease in our setting. The aim of this study was to describe the frequency with which index neonatal surgical conditions are seen within our setting and to document the 30-day outcome of these patients. This was a single-centre prospective observational study in which all neonates with paediatric surgical pathology referred to the paediatric surgical unit with a corrected gestational age of 28 days were included. Necrotising enterocolitis was the most frequent reason for referral to the paediatric surgical unit (n = 68, 34.34%). Gastroschisis was the most frequent congenital anomaly referred (n = 20, 10.10%). The overall morbidity was 57.58%. Surgical complications contributed to 18.51% of morbidities. The development of gram negative nosocomial sepsis was the most frequent cause of morbidity (n = 98, 50.78%). Mortality at 30 days was 21.74% (n = 40). Sepsis contributed to mortality in 35 patients (87.5%), 16 of which had gram negative sepsis. Gram-negative sepsis was a major contributing factor in the development of morbidity and mortality in our cohort. Prevention and improvement in infection control are imperative if we are to improve outcomes in our surgical neonates.
Identifiants
pubmed: 33740107
doi: 10.1007/s00383-021-04881-7
pii: 10.1007/s00383-021-04881-7
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
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