Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack.


Journal

Cell reports. Medicine
ISSN: 2666-3791
Titre abrégé: Cell Rep Med
Pays: United States
ID NLM: 101766894

Informations de publication

Date de publication:
16 03 2021
Historique:
received: 15 09 2020
revised: 16 12 2020
accepted: 04 02 2021
entrez: 25 3 2021
pubmed: 26 3 2021
medline: 26 3 2021
Statut: epublish

Résumé

Therapeutic vaccination regimens inducing clinically effective tumor-specific CD8

Identifiants

pubmed: 33763654
doi: 10.1016/j.xcrm.2021.100209
pii: S2666-3791(21)00020-3
pmc: PMC7974551
doi:

Substances chimiques

Alarmins 0
Antibodies, Neutralizing 0
Cancer Vaccines 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Pagination

100209

Informations de copyright

© 2021 The Author(s).

Déclaration de conflit d'intérêts

S.S., J.R., U.B., and K.K.O. are employees and stock option holders of Hookipa Pharma, Inc. D.D.P. is a founder, consultant, shareholder, and stock option holder of Hookipa Pharma, Inc. W.V.B., S.M.K., S.S., S.D., U.B., D.D.P., D.M., and K.K.O. are listed as inventors on patents describing artARENA vector technology. W.V.B. and D.D.P. are married.

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Auteurs

Weldy V Bonilla (WV)

University of Basel, Department of Biomedicine, Basel, Switzerland.

Nicole Kirchhammer (N)

University of Basel, Department of Biomedicine, Basel, Switzerland.

Anna-Friederike Marx (AF)

University of Basel, Department of Biomedicine, Basel, Switzerland.

Sandra M Kallert (SM)

University of Basel, Department of Biomedicine, Basel, Switzerland.

Magdalena A Krzyzaniak (MA)

University of Basel, Department of Biomedicine, Basel, Switzerland.

Min Lu (M)

University of Basel, Department of Biomedicine, Basel, Switzerland.

Stéphanie Darbre (S)

Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.

Sarah Schmidt (S)

Hookipa Pharma Inc., Vienna, Austria.

Josipa Raguz (J)

Hookipa Pharma Inc., Vienna, Austria.

Ursula Berka (U)

Hookipa Pharma Inc., Vienna, Austria.

Ilena Vincenti (I)

Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.

Mindaugas Pauzuolis (M)

Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.

Romy Kerber (R)

Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.

Sabine Hoepner (S)

Tumor Immunology, Department for BioMedical Research, University of Bern, Bern, Switzerland.

Stephan Günther (S)

Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.

Carsten Magnus (C)

Institute of Virology, University of Zurich, Zurich, Switzerland.

Doron Merkler (D)

Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.
Division of Clinical Pathology, University Hospitals of Geneva, Geneva, Switzerland.

Klaus K Orlinger (KK)

Hookipa Pharma Inc., Vienna, Austria.

Alfred Zippelius (A)

University of Basel, Department of Biomedicine, Basel, Switzerland.
Medical Oncology, University Hospital Basel, Basel, Switzerland.

Daniel D Pinschewer (DD)

University of Basel, Department of Biomedicine, Basel, Switzerland.

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Classifications MeSH