Pulmonary Madurella mycetomatis mycetoma secondary to knee eumycetoma, Senegal.


Journal

PLoS neglected tropical diseases
ISSN: 1935-2735
Titre abrégé: PLoS Negl Trop Dis
Pays: United States
ID NLM: 101291488

Informations de publication

Date de publication:
03 2021
Historique:
entrez: 25 3 2021
pubmed: 26 3 2021
medline: 29 6 2021
Statut: epublish

Résumé

Mycetoma is a neglected tropical disease which is endemic in Senegal. Although this subcutaneous mycosis is most commonly found on the foot, extrapodal localisations have also been found, including on the leg, knee, thigh, hand, and arm. To our knowledge, no case of blood-spread eumycetoma has been reported in Senegal. Here, we report a case of pulmonary mycetoma secondary to a Madurella mycetomatis knee eumycetoma. The patient was a 41-year-old farmer living in Louga, Senegal, where the Sudano-Sahelian climate is characterised by a short and unstable rainy season and a steppe vegetation. He suffered a trauma to the right more than 20 years previously and had received treatment for more than 10 years with traditional medicine. He consulted at Le Dantec University Hospital in Dakar for treatment of a right knee mycetoma which had been diagnosed more than 10 years ago. He had experienced a chronic cough for more than a year; tuberculosis documentation was negative. Grains collected from the knee and the sputum isolated M. mycetomatis, confirmed by the rRNA gene ITS regions nucleotide sequence analysis. An amputation above the knee was performed, and antibacterial and antifungal therapy was started with amoxicillin-clavulanic acid and terbinafine. The patient died within a month of his discharge from hospital.

Identifiants

pubmed: 33764976
doi: 10.1371/journal.pntd.0009238
pii: PNTD-D-20-01386
pmc: PMC7993608
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0009238

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Khadim Diongue (K)

Laboratory of Parasitology and Mycology, Aristide Le Dantec University Hospital, Dakar, Senegal.
Service of Parasitology-Mycology, Faculty of Medicine, Pharmacy and Odontology, Cheikh Anta Diop University of Dakar, Dakar, Senegal.

Mamadou Alpha Diallo (MA)

Laboratory of Parasitology and Mycology, Aristide Le Dantec University Hospital, Dakar, Senegal.

Lamine Sarr (L)

Service of Orthopedics, Aristide Le Dantec University Hospital, Dakar, Senegal.

Mame Cheikh Seck (MC)

Laboratory of Parasitology and Mycology, Aristide Le Dantec University Hospital, Dakar, Senegal.
Service of Parasitology-Mycology, Faculty of Medicine, Pharmacy and Odontology, Cheikh Anta Diop University of Dakar, Dakar, Senegal.

Ludivine Bréchard (L)

University Hospital Institute Méditerranée Infection, Marseille, France.

Mouhamadou Ndiaye (M)

Laboratory of Parasitology and Mycology, Aristide Le Dantec University Hospital, Dakar, Senegal.
Service of Parasitology-Mycology, Faculty of Medicine, Pharmacy and Odontology, Cheikh Anta Diop University of Dakar, Dakar, Senegal.

Aida Sadikh Badiane (AS)

Laboratory of Parasitology and Mycology, Aristide Le Dantec University Hospital, Dakar, Senegal.
Service of Parasitology-Mycology, Faculty of Medicine, Pharmacy and Odontology, Cheikh Anta Diop University of Dakar, Dakar, Senegal.

Stéphane Ranque (S)

University Hospital Institute Méditerranée Infection, Marseille, France.

Daouda Ndiaye (D)

Laboratory of Parasitology and Mycology, Aristide Le Dantec University Hospital, Dakar, Senegal.
Service of Parasitology-Mycology, Faculty of Medicine, Pharmacy and Odontology, Cheikh Anta Diop University of Dakar, Dakar, Senegal.

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Classifications MeSH