Carotenoid Production in Escherichia coli: Case of Acyclic Carotenoids.
Acyclic carotenoids
C30 carotenoids
Combinatorial biosynthesis
Crocin
Escherichia coli
Journal
Advances in experimental medicine and biology
ISSN: 0065-2598
Titre abrégé: Adv Exp Med Biol
Pays: United States
ID NLM: 0121103
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
30
3
2021
pubmed:
31
3
2021
medline:
7
4
2021
Statut:
ppublish
Résumé
Among isoprenoids, carotenoids were the first group of compounds which were synthesized from foreign genes in non-carotenogenic Escherichia coli as a heterologous host. A great variety of carotenoids have been shown to be produced in E. coli due to the introduction of combinations of carotenoid biosynthesis genes, which were isolated from carotenogenic organisms. Carotenoids that have been produced in E. coli are mostly cyclic carotenoids that retain carbon 40 (C40) basic structure, except for acyclic carotene lycopene. On the other hand, acyclic carotenoids, which can also be produced in E. coli, comprise a group of carotenoids with diverse chain lengths, i.e., with C20, C30, C40, or C50 basic skeleton. As for acyclic C30, C40, and C50 carotenoids, carotenogenic genes of bacterial origin were needed, while a cleavage dioxygenase gene of higher-plant origin was utilized for the synthesis of acyclic C20 carotenoids. The present chapter is a review on the biosynthesis of such diverse acyclic carotenoids at the gene level.
Identifiants
pubmed: 33783742
doi: 10.1007/978-981-15-7360-6_17
doi:
Substances chimiques
Carotenoids
36-88-4
Lycopene
SB0N2N0WV6
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
201-208Références
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