Osteopathy in mild adrenal Cushing's syndrome and Cushing disease.

Bone Density Bone Density Conservation Agents / therapeutic use Cushing Syndrome / complications Humans Osteoporosis / drug therapy Pituitary ACTH Hypersecretion / complications
adrenal incidentaloma bone mineral density bone quality cushing disease fractures glucocorticoids

Journal

Best practice & research. Clinical endocrinology & metabolism
ISSN: 1878-1594
Titre abrégé: Best Pract Res Clin Endocrinol Metab
Pays: Netherlands
ID NLM: 101120682

Informations de publication

Date de publication:
03 2021
Historique:
pubmed: 3 4 2021
medline: 21 9 2021
entrez: 2 4 2021
Statut: ppublish

Résumé

Pathophysiology and effects of endogenous glucocorticoid (GC) excess on skeletal endpoints as well as awareness and management of bone fragility are reviewed. Cushing's syndrome (CS) increase the risk of fracture affecting prevalently bone quality. Bone antiresorptive agents (SERMs, bisphosphonates and denosumab) as well as teriparatide increase bone mineral density and in some instances reduce fracture risk. Awareness and management of bone health in CS can be improved.

Identifiants

DOI: 10.1016/j.beem.2021.101515 PMID: 33795196
pubmed: 33795196
pii: S1521-690X(21)00032-4
doi: 10.1016/j.beem.2021.101515
pii:
doi:

Substances chimiques

Bone Density Conservation Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

101515

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Stefano Frara (S)

Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy.

Agnese Allora (A)

Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy.

Luigi di Filippo (L)

Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy.

Anna Maria Formenti (AM)

Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy.

Paola Loli (P)

Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy.

Elisabetta Polizzi (E)

Dentistry Unit, IRCCS Ospedale San Raffaele, Milan, Italy.

Daniele Tradati (D)

Department of Orthopedics and Traumatology, IRCCS Ospedale San Raffaele, Milan, Italy.

Fabio Massimo Ulivieri (FM)

Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy.

Andrea Giustina (A)

Institute of Endocrine and Metabolic Sciences, Università Vita-Salute San Raffaele, IRCCS Ospedale San Raffaele, Milan, Italy. Electronic address: giustina.andrea@hsr.it.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Densité osseuse › Osteopathy in mild adrenal Cushing's syndrome...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents de maintien de la densité osseuse › Osteopathy in mild adrenal Cushing's syndrome...
questionsmedicales.fr › Maladies endocriniennes › Maladies des surrénales › Hypercorticisme › Syndrome de Cushing › Osteopathy in mild adrenal Cushing's syndrome...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Osteopathy in mild adrenal Cushing's syndrome...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Maladies osseuses métaboliques › Ostéoporose › Osteopathy in mild adrenal Cushing's syndrome...
questionsmedicales.fr › Maladies endocriniennes › Maladies de l'hypophyse › Hyperpituitarisme › Hypersécrétion hypophysaire d'ACTH › Osteopathy in mild adrenal Cushing's syndrome...