Risk profile, antithrombotic treatment and clinical outcomes of patients in Nordic countries with atrial fibrillation - results from the GARFIELD-AF registry.


Journal

Annals of medicine
ISSN: 1365-2060
Titre abrégé: Ann Med
Pays: England
ID NLM: 8906388

Informations de publication

Date de publication:
12 2021
Historique:
entrez: 5 4 2021
pubmed: 6 4 2021
medline: 14 10 2021
Statut: ppublish

Résumé

The objective was to evaluate the clinical characteristics, management and two-year outcomes of patients with newly diagnosed non-valvular atrial fibrillation at risk for stroke in Nordic countries. We examined the baseline characteristics, antithrombotic treatment, and two-year clinical outcomes of patients from four Nordic countries. A total of 52,080 patients were enrolled in the GARFIELD-AF. Out of 29,908 European patients, 2,396 were recruited from Nordic countries. The use of oral anticoagulants, alone or in combination with antiplatelet (AP), was higher in Nordic patients in all CHA Nordic patients had significantly higher major bleeding than Non-Nordic-European patients. In contrast, rates of all-cause mortality and non-haemorrhagic stroke/SE were comparable. Unique identifier: NCT01090362. URL: http://www.clinicaltrials.gov. Nordic countries had significantly higher major bleeding than Non-Nordic-European countries. Rates of mortality and non-haemorrhagic stroke/SE were similar .

Identifiants

pubmed: 33818226
doi: 10.1080/07853890.2021.1893897
pmc: PMC8023647
doi:

Substances chimiques

Anticoagulants 0
Fibrinolytic Agents 0
Platelet Aggregation Inhibitors 0

Banques de données

ClinicalTrials.gov
['NCT01090362']

Types de publication

Evaluation Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

485-494

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Auteurs

Marita Knudsen Pope (MK)

Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Hamar Hospital, Innlandet Hospital Trust, Hamar, Norway.

Dan Atar (D)

Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway.

Arne Svilaas (A)

Nymoen Medical Centre, Kongsberg, Norway.
Lipid Clinic, Oslo University Hospital, Oslo, Norway.

Torstein Hole (T)

Clinic of Medicine and Rehabilitation, More and Romsdal Hospital Trust, Alesund, Norway.
Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, NTNU - Norwegian University of Science and Technology, Trondheim, Norway.

Jørn Dalsgaard Nielsen (JD)

Department of Cardiology, Copenhagen University Hospital, Copenhagen University, Copenhagen, Denmark.

Ulrik Hintze (U)

Department of Cardiology, Hospital of South West Jutland, Esbjerg, University of Southern Denmark, Denmark.

Milita Crisby (M)

Department of Neurobiology, Care Science and Society, Karolinska University Hospital, Stockholm, Sweden.

Pekka Raatikainen (P)

Department of Cardiology, Heart and Lung Center, Helsinki University Hospital, Tampere, Finland.

K E Juhani Airaksinen (KEJ)

Heart Centre, Turku University Hospital and University of Turku, Turku, Finland.

Saverio Virdone (S)

Thrombosis Research Institute, London, UK.

Karen Pieper (K)

Thrombosis Research Institute, London, UK.

Gloria Kayani (G)

Thrombosis Research Institute, London, UK.

Jean-Yves Le Heuzey (JY)

Georges Pompidou Hospital, René Descartes University, Paris, France.

Jan Steffel (J)

Division of Electrophysiology and Pacing, Department of Cardiology, University Heart Center Zurich, Zurich, Switzerland.

Janina Stepinska (J)

Institute of Cardiology, Intensive Cardiac Therapy Clinic, Warsaw, Poland.

Jean-Pierre Bassand (JP)

Thrombosis Research Institute, London, UK.
University of Besançon, Besancon, France.

A John Camm (AJ)

Cardiology Clinical Academic Group Molecular & Clinical Sciences Research Institute, St. George's University of London, London, UK.

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