Hydroxyzine-induced priapism.


Journal

The American journal of emergency medicine
ISSN: 1532-8171
Titre abrégé: Am J Emerg Med
Pays: United States
ID NLM: 8309942

Informations de publication

Date de publication:
10 2021
Historique:
received: 02 02 2021
revised: 11 03 2021
accepted: 20 03 2021
pubmed: 11 4 2021
medline: 25 2 2023
entrez: 10 4 2021
Statut: ppublish

Résumé

Priapism is a severe urologic condition requiring emergency management. Ischemic priapism is the most common subtype which is characterized by a long-lasting, painful, and rigid erection which can be caused by medications with alpha-adrenergic properties such as hydroxyzine. Typically, medication-induced priapism is reported at therapeutic doses and few case reports exist implicating medication overdose as the cause. We report a case of a patient taking hypercompliant doses of hydroxyzine hydrochloride for worsening insomnia (200-600 mg), including the night before admission. Blood-gas analysis of blood from the right corpora was completed and revealed a pH of 6.736, pCO

Identifiants

pubmed: 33836933
pii: S0735-6757(21)00253-9
doi: 10.1016/j.ajem.2021.03.066
pii:
doi:

Substances chimiques

Histamine H1 Antagonists 0
Hydroxyzine 30S50YM8OG

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

375.e5-375.e6

Informations de copyright

Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Christopher Olson (C)

Jesse Brown VA Medical Center, 820 South Damen Avenue, Chicago, IL 60612, United States of America. Electronic address: Christopher.Olson1@va.gov.

Archana Jhawar (A)

Jesse Brown VA Medical Center, 820 South Damen Avenue, Chicago, IL 60612, United States of America; University of Illinois at Chicago, 833 S Wood Street, Chicago, IL 60612, United States of America.

Zane Elfessi (Z)

Jesse Brown VA Medical Center, 820 South Damen Avenue, Chicago, IL 60612, United States of America; University of Illinois at Chicago, 833 S Wood Street, Chicago, IL 60612, United States of America.

Richard Doyle (R)

Jesse Brown VA Medical Center, 820 South Damen Avenue, Chicago, IL 60612, United States of America.

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Classifications MeSH