Decoding allosteric regulation by the acyl carrier protein.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
20 04 2021
Historique:
entrez: 13 4 2021
pubmed: 14 4 2021
medline: 15 12 2021
Statut: ppublish

Résumé

Enzymes in multistep metabolic pathways utilize an array of regulatory mechanisms to maintain a delicate homeostasis [K. Magnuson, S. Jackowski, C. O. Rock, J. E. Cronan, Jr,

Identifiants

pubmed: 33846262
pii: 2025597118
doi: 10.1073/pnas.2025597118
pmc: PMC8072227
pii:
doi:

Substances chimiques

Acyl Carrier Protein 0
Escherichia coli Proteins 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM031749
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM095970
Pays : United States

Déclaration de conflit d'intérêts

The authors declare no competing interest.

Références

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Auteurs

Terra Sztain (T)

Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0358.

Thomas G Bartholow (TG)

Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0358.

D John Lee (DJ)

Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0358.

Lorenzo Casalino (L)

Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0358.

Andrew Mitchell (A)

Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0358.

Megan A Young (MA)

Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0358.

Jianing Wang (J)

Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0358.

J Andrew McCammon (JA)

Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0358; jmccammon@ucsd.edu mburkart@ucsd.edu.
Department of Pharmacology, University of California San Diego, La Jolla, CA 92093-0340.

Michael D Burkart (MD)

Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093-0358; jmccammon@ucsd.edu mburkart@ucsd.edu.

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Classifications MeSH