A kinetic view of clathrin assembly and endocytic cargo sorting.

Cell Movement Clathrin / metabolism Clathrin-Coated Vesicles / metabolism Endocytosis Protein Transport
Cargo sorting Endocytosis Hsc70 Knetic proofreading

Journal

Current opinion in cell biology
ISSN: 1879-0410
Titre abrégé: Curr Opin Cell Biol
Pays: England
ID NLM: 8913428

Informations de publication

Date de publication:
08 2021
Historique:
received: 28 11 2020
revised: 10 02 2021
accepted: 12 02 2021
pubmed: 18 4 2021
medline: 27 10 2021
entrez: 17 4 2021
Statut: ppublish

Résumé

Specificity and sensitivity in biochemical reactions can be achieved through regulation of equilibrium binding affinity or through proofreading mechanisms that allow for the dissociation of unwanted intermediates. In this essay, we aim to provide our perspectives on how the concept of kinetic proofreading might apply in the context of cargo sorting in clathrin-mediated endocytosis.

Identifiants

DOI: 10.1016/j.ceb.2021.02.010 PMID: 33865229
pubmed: 33865229
pii: S0955-0674(21)00031-4
doi: 10.1016/j.ceb.2021.02.010
pii:
doi:

Substances chimiques

Clathrin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

130-138

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of interest statement Nothing declared.

Auteurs

Min Wu (M)

Department of Cell Biology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06520-8002, USA. Electronic address: wu.min@yale.edu.

Xudong Wu (X)

Howard Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA, 02115, USA.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques › Mouvement cellulaire › A kinetic view of clathrin assembly and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines du transport vésiculaire › Clathrine › A kinetic view of clathrin assembly and...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Vésicules de transport › Vésicules tapissées › Vésicules tapissées de clathrine › A kinetic view of clathrin assembly and...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Endocytose › A kinetic view of clathrin assembly and...
questionsmedicales.fr › Métabolisme › Transport biologique › Transport des protéines › A kinetic view of clathrin assembly and...