Large-scale sequencing of flatfish genomes provides insights into the polyphyletic origin of their specialized body plan.
Journal
Nature genetics
ISSN: 1546-1718
Titre abrégé: Nat Genet
Pays: United States
ID NLM: 9216904
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
received:
24
06
2020
accepted:
05
03
2021
pubmed:
21
4
2021
medline:
16
6
2021
entrez:
20
4
2021
Statut:
ppublish
Résumé
The evolutionary and genetic origins of the specialized body plan of flatfish are largely unclear. We analyzed the genomes of 11 flatfish species representing 9 of the 14 Pleuronectiforme families and conclude that Pleuronectoidei and Psettodoidei do not form a monophyletic group, suggesting independent origins from different percoid ancestors. Genomic and transcriptomic data indicate that genes related to WNT and retinoic acid pathways, hampered musculature and reduced lipids might have functioned in the evolution of the specialized body plan of Pleuronectoidei. Evolution of Psettodoidei involved similar but not identical genes. Our work provides valuable resources and insights for understanding the genetic origins of the unusual body plan of flatfishes.
Identifiants
pubmed: 33875864
doi: 10.1038/s41588-021-00836-9
pii: 10.1038/s41588-021-00836-9
pmc: PMC8110480
doi:
Banques de données
figshare
['10.6084/m9.figshare.13664201.v1']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
742-751Références
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