Hyphenated sample preparation-electrospray and nano-electrospray ionization mass spectrometry for biofluid analysis.

Miniaturization Solid Phase Microextraction / methods Specimen Handling Spectrometry, Mass, Electrospray Ionization / methods
Biological fluids Electrospray ionization-mass spectrometry (ESI-MS) Nano-ESI-MS Sample preparation Stand-alone mass spectrometry

Journal

Journal of chromatography. A
ISSN: 1873-3778
Titre abrégé: J Chromatogr A
Pays: Netherlands
ID NLM: 9318488

Informations de publication

Date de publication:
07 Jun 2021
Historique:
received: 14 12 2020
revised: 18 03 2021
accepted: 19 03 2021
pubmed: 24 4 2021
medline: 21 5 2021
entrez: 23 4 2021
Statut: ppublish

Résumé

Stand-alone electrospray ionization mass spectrometry (ESI-MS) has been advancing through enhancements in throughput, selectivity and sensitivity of mass spectrometers. Unlike traditional MS techniques which usually require extensive offline sample preparation and chromatographic separation, many sample preparation techniques are now directly coupled with stand-alone MS to enable outstanding throughput for bioanalysis. In this review, we summarize the different sample clean-up and/or analyte enrichment strategies that can be directly coupled with ESI-MS and nano-ESI-MS for the analysis of biological fluids. The overview covers the hyphenation of different sample preparation techniques including solid phase extraction (SPE), solid phase micro-extraction (SPME), slug flow micro-extraction/nano-extraction (SFME/SFNE), liquid extraction surface analysis (LESA), extraction electrospray, extraction using digital microfluidics (DMF), and electrokinetic extraction (EkE) with ESI-MS and nano-ESI-MS.

Identifiants

DOI: 10.1016/j.chroma.2021.462086 PMID: 33892255
pubmed: 33892255
pii: S0021-9673(21)00210-7
doi: 10.1016/j.chroma.2021.462086
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

462086

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare no competing financial interests.

Auteurs

Ibraam E Mikhail (IE)

ARC Training Centre for Portable Analytical Separation Technologies (ASTech), Australia; Australian Centre for Research on Separation Science (ACROSS), School of Natural Sciences (Chemistry), University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia; Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, 35516, Egypt.

Masoomeh Tehranirokh (M)

ARC Training Centre for Portable Analytical Separation Technologies (ASTech), Australia; Trajan Scientific and Medical, Ringwood, VIC, 3134, Australia.

Andrew A Gooley (AA)

ARC Training Centre for Portable Analytical Separation Technologies (ASTech), Australia; Trajan Scientific and Medical, Ringwood, VIC, 3134, Australia.

Rosanne M Guijt (RM)

ARC Training Centre for Portable Analytical Separation Technologies (ASTech), Australia; Centre for Regional and Rural Futures, Deakin University, Geelong, VIC, 3220, Australia.

Michael C Breadmore (MC)

ARC Training Centre for Portable Analytical Separation Technologies (ASTech), Australia; Australian Centre for Research on Separation Science (ACROSS), School of Natural Sciences (Chemistry), University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia. Electronic address: Michael.Breadmore@utas.edu.au.

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Classifications MeSH

questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Miniaturisation › Hyphenated sample preparation-electrospray and...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Fractionnement chimique › Extraction en phase solide › Microextraction en phase solide › Hyphenated sample preparation-electrospray and...
questionsmedicales.fr › Techniques d'investigation › Techniques de laboratoire clinique › Manipulation d'échantillons › Hyphenated sample preparation-electrospray and...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse ESI › Hyphenated sample preparation-electrospray and...