Coordinating the morphogenesis-differentiation balance by tweaking the cytokinin-gibberellin equilibrium.
Cell Differentiation
/ genetics
Cytokinins
/ genetics
Gene Expression Regulation, Plant
/ genetics
Gibberellins
/ metabolism
Solanum lycopersicum
/ genetics
Morphogenesis
/ genetics
Plant Development
/ genetics
Plant Leaves
/ genetics
Plant Proteins
/ genetics
Plants, Genetically Modified
/ genetics
Transcription Factors
/ genetics
Journal
PLoS genetics
ISSN: 1553-7404
Titre abrégé: PLoS Genet
Pays: United States
ID NLM: 101239074
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
received:
30
12
2020
accepted:
06
04
2021
revised:
06
05
2021
pubmed:
27
4
2021
medline:
28
8
2021
entrez:
26
4
2021
Statut:
epublish
Résumé
Morphogenesis and differentiation are important stages in organ development and shape determination. However, how they are balanced and tuned during development is not fully understood. In the compound leaved tomato, an extended morphogenesis phase allows for the initiation of leaflets, resulting in the compound form. Maintaining a prolonged morphogenetic phase in early stages of compound-leaf development in tomato is dependent on delayed activity of several factors that promote differentiation, including the CIN-TCP transcription factor (TF) LA, the MYB TF CLAU and the plant hormone Gibberellin (GA), as well as on the morphogenesis-promoting activity of the plant hormone cytokinin (CK). Here, we investigated the genetic regulation of the morphogenesis-differentiation balance by studying the relationship between LA, CLAU, TKN2, CK and GA. Our genetic and molecular examination suggest that LA is expressed earlier and more broadly than CLAU and determines the developmental context of CLAU activity. Genetic interaction analysis indicates that LA and CLAU likely promote differentiation in parallel genetic pathways. These pathways converge downstream on tuning the balance between CK and GA. Comprehensive transcriptomic analyses support the genetic data and provide insights into the broader molecular basis of differentiation and morphogenesis processes in plants.
Identifiants
pubmed: 33901177
doi: 10.1371/journal.pgen.1009537
pii: PGENETICS-D-20-01955
pmc: PMC8102002
doi:
Substances chimiques
Cytokinins
0
Gibberellins
0
Plant Proteins
0
Transcription Factors
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e1009537Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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