Expanded collectin family in bullfrog (Rana catesbeiana): Identification and characterization of plasma collectins.
Agglutination
/ immunology
Animals
Bacterial Adhesion
/ immunology
Carbohydrate Metabolism
/ immunology
Carbohydrates
/ immunology
Collectins
/ blood
Escherichia coli
/ immunology
Immunity, Innate
/ genetics
Larva
/ immunology
Mannose-Binding Lectin
/ blood
Phylogeny
Pulmonary Surfactant-Associated Protein D
/ blood
Rana catesbeiana
/ metabolism
Collectin
Evolution
Expression
Molecular structure
Rana catesbeiana
Saccharide recognition
Journal
Developmental and comparative immunology
ISSN: 1879-0089
Titre abrégé: Dev Comp Immunol
Pays: United States
ID NLM: 7708205
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
05
03
2021
revised:
19
04
2021
accepted:
19
04
2021
pubmed:
29
4
2021
medline:
3
3
2022
entrez:
28
4
2021
Statut:
ppublish
Résumé
BLAST searches against databases for the bullfrog (Rana catesbeiana), using the collectin sequence previously identified in tadpoles, revealed the presence of at least 20 members of the collectin gene family. Phylogenetic analysis demonstrated that the bullfrog possesses expanded gene subfamilies encoding mannose-binding lectin (MBL) and pulmonary surfactant-associated protein D (PSAPD). Two collectins, of 20 kDa (PSAPD1) and 25 kDa (PSAPD6), were purified as a mixture from adult bullfrog plasma using affinity chromatography. These collectins were present as an oligomer of ~400 kDa in their native state, and showed Ca
Identifiants
pubmed: 33909995
pii: S0145-305X(21)00116-6
doi: 10.1016/j.dci.2021.104108
pii:
doi:
Substances chimiques
Carbohydrates
0
Collectins
0
Mannose-Binding Lectin
0
Pulmonary Surfactant-Associated Protein D
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
104108Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.