Implementation of a regional video multidisciplinary team meeting is associated with an improved prognosis for patients with oesophageal cancer A mixed methods approach.


Journal

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
ISSN: 1532-2157
Titre abrégé: Eur J Surg Oncol
Pays: England
ID NLM: 8504356

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 26 02 2021
accepted: 15 04 2021
pubmed: 1 5 2021
medline: 17 2 2022
entrez: 30 4 2021
Statut: ppublish

Résumé

Studies have shown that multidisciplinary team meetings (MDTM) improve diagnostic work-up and treatment-decisions. This study aims to evaluate the influence of implementing a regional-video-Upper-GI-MDTM (uMDTM) for oesophageal cancer (OC) on the number of patients discussed, treatment-decisions, perspectives of involved clinicians and overall survival (OS) in the Eindhoven Upper-GI Network consisting of 1 resection hospital and 5 referring hospitals. Between 2012 and 2018, patients diagnosed with OC within this region, were selected from the Netherlands Cancer Registry(n = 1119). From 2014, an uMDTM was gradually implemented and a mixed-method quantitative and qualitative design was used to analyse changes. Quantitative outcomes were described before and after implementation of the uMDTM. Clinicians were interviewed to assess their perspectives regarding the uMDTM. After participation in the uMDTM more patients were discussed in an MDTM (80%-89%,p < 0.0001) and involvement of a resection centre during the uMDTM increased (43%-82%,p < 0.0001). The proportion of patients diagnosed with potentially curable OC (cT1-4a-x, any cN, cM0) remained stable (59%-61%, p = 0.452). Endoscopic or surgical resections were performed more often (28%-34%,p = 0.034) and the use of best supportive care decreased (21%-15%,p = 0.018). In the qualitative part an improved knowledge, collaboration and discussion was perceived due to implementation of the uMDTM. Three-year OS for all OC patients increased after the implementation of the uMDTM (24%-30%,p = 0.025). Implementation of a regional Upper-GI MDTM was associated with an increase in patients discussed with a resection centre, more curative resections and a better OS. It remains to be elucidated which factors in the clinical pathway explain this observed improved survival.

Sections du résumé

BACKGROUND BACKGROUND
Studies have shown that multidisciplinary team meetings (MDTM) improve diagnostic work-up and treatment-decisions. This study aims to evaluate the influence of implementing a regional-video-Upper-GI-MDTM (uMDTM) for oesophageal cancer (OC) on the number of patients discussed, treatment-decisions, perspectives of involved clinicians and overall survival (OS) in the Eindhoven Upper-GI Network consisting of 1 resection hospital and 5 referring hospitals.
METHODS METHODS
Between 2012 and 2018, patients diagnosed with OC within this region, were selected from the Netherlands Cancer Registry(n = 1119). From 2014, an uMDTM was gradually implemented and a mixed-method quantitative and qualitative design was used to analyse changes. Quantitative outcomes were described before and after implementation of the uMDTM. Clinicians were interviewed to assess their perspectives regarding the uMDTM.
RESULTS RESULTS
After participation in the uMDTM more patients were discussed in an MDTM (80%-89%,p < 0.0001) and involvement of a resection centre during the uMDTM increased (43%-82%,p < 0.0001). The proportion of patients diagnosed with potentially curable OC (cT1-4a-x, any cN, cM0) remained stable (59%-61%, p = 0.452). Endoscopic or surgical resections were performed more often (28%-34%,p = 0.034) and the use of best supportive care decreased (21%-15%,p = 0.018). In the qualitative part an improved knowledge, collaboration and discussion was perceived due to implementation of the uMDTM. Three-year OS for all OC patients increased after the implementation of the uMDTM (24%-30%,p = 0.025).
CONCLUSIONS CONCLUSIONS
Implementation of a regional Upper-GI MDTM was associated with an increase in patients discussed with a resection centre, more curative resections and a better OS. It remains to be elucidated which factors in the clinical pathway explain this observed improved survival.

Identifiants

pubmed: 33926781
pii: S0748-7983(21)00448-0
doi: 10.1016/j.ejso.2021.04.020
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

3088-3096

Informations de copyright

Copyright © 2021 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest None declared. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Auteurs

Josianne C H B M Luijten (JCHBM)

Department of Research and Development, Netherlands Comprehensive Cancer Organization, Utrecht, the Netherlands.

Vera C Haagsman (VC)

Department of Research and Development, Netherlands Comprehensive Cancer Organization, Utrecht, the Netherlands.

Misha D P Luyer (MDP)

Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.

Pauline A J Vissers (PAJ)

Department of Research and Development, Netherlands Comprehensive Cancer Organization, Utrecht, the Netherlands.

Joost Nederend (J)

Department of Radiology, Catharina Hospital, Eindhoven, the Netherlands.

Clément Huysentruyt (C)

Department of Pathology, Catharina Hospital, Eindhoven, the Netherlands.

Geert-Jan Creemers (GJ)

Department of Oncology, Catharina Hospital, Eindhoven, the Netherlands.

Wouter Curvers (W)

Department of Gastroenterology, Catharina Hospital, Eindhoven, the Netherlands.

Maurice van der Sangen (M)

Department of Radiotherapy, Catharina Hospital, Eindhoven, the Netherlands.

Fanny B M Heesakkers (FBM)

Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.

Ruud W M Schrauwen (RWM)

Department of Gastroenterology, Bernhoven Hospital, Uden, the Netherlands.

Matthias C Jürgens (MC)

Department Gastroenterology, St. Jans Gasthuis Weert, the Netherlands.

Erik H C J Buster (EHCJ)

Department of Gastroenterology, Maxima Medical Centre, Veldhoven, the Netherlands.

Jeroen Vincent (J)

Department of Oncology, Elkerliek Hospital, Helmond, the Netherlands.

Jan Kees Kneppelhout (JK)

Department of Gastroenterology, Sint Anna Hospital, Geldrop, the Netherlands.

Rob H A Verhoeven (RHA)

Department of Research and Development, Netherlands Comprehensive Cancer Organization, Utrecht, the Netherlands; Department of Surgery, Radboud University Medical Centre, Nijmegen, the Netherlands.

Grard A P Nieuwenhuijzen (GAP)

Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands. Electronic address: Grard.nieuwenhuijzen@catharinaziekenhuis.nl.

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