Saccharomyces cerevisiae fungemia: Risk factors, outcome and links with S. boulardii-containing probiotic administration.
Adult
Aged
Aged, 80 and over
Antifungal Agents
/ therapeutic use
Enteral Nutrition
/ adverse effects
Female
Fungemia
/ drug therapy
Humans
Intensive Care Units
Male
Middle Aged
Parenteral Nutrition
/ adverse effects
Probiotics
/ administration & dosage
Retrospective Studies
Risk Factors
Saccharomyces boulardii
/ isolation & purification
Saccharomyces cerevisiae
/ isolation & purification
Treatment Outcome
Young Adult
Fungemia
Probiotics
Saccharomyces boulardii
Journal
Infectious diseases now
ISSN: 2666-9919
Titre abrégé: Infect Dis Now
Pays: France
ID NLM: 101775152
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
received:
21
07
2020
revised:
01
12
2020
accepted:
04
12
2020
entrez:
3
5
2021
pubmed:
4
5
2021
medline:
27
8
2021
Statut:
ppublish
Résumé
Saccharomyces cerevisiae fungemia: risk factors, outcome and links with S. boulardii-containing probiotic administration. The aim of our study was to review cases of S. cerevisiae fungemia along with the corresponding risk factors (including S. boulardii probiotic intake), treatment and outcomes. Retrospective study (2005-2017) of S. cerevisiae fungemia. All the data were extracted from medical files. We identified 10 patients with S. cerevisiae fungemia. Mean age was 59.4 years (range 21-88). Four fifths (80%) were on total parenteral or enteral nutrition, 70% had a central venous line, and 30% were admitted in an Intensive Care Unit (ICU). S. boulardii-containing probiotic prescription was identified in 6 subjects. Three patients with no risk factors such as ICU or central venous catheter were 80 years old or more. Mortality rate was 50%. S. cerevisiae fungemia is a rare but life-threatening infection, associated with intake of probiotics containing S. boulardii. Besides classical risk factors, older age should be a contraindication for these probiotics.
Identifiants
pubmed: 33934809
pii: S2666-9919(20)00025-1
doi: 10.1016/j.idnow.2020.12.003
pii:
doi:
Substances chimiques
Antifungal Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
293-295Informations de copyright
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