A candidate gene identified in converting platycoside E to platycodin D from Platycodon grandiflorus by transcriptome and main metabolites analysis.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
07 05 2021
Historique:
received: 28 10 2020
accepted: 23 04 2021
entrez: 8 5 2021
pubmed: 9 5 2021
medline: 21 10 2021
Statut: epublish

Résumé

Platycodin D and platycoside E are two triterpenoid saponins in Platycodon grandiflorus, differing only by two glycosyl groups structurally. Studies have shown β-Glucosidase from bacteria can convert platycoside E to platycodin D, indicating the potential existence of similar enzymes in P. grandiflorus. An L

Identifiants

pubmed: 33963244
doi: 10.1038/s41598-021-89294-1
pii: 10.1038/s41598-021-89294-1
pmc: PMC8105318
doi:

Substances chimiques

Saponins 0
platycoside D 0
platycoside E 0
Oleanolic Acid 6SMK8R7TGJ

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

9810

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Auteurs

Xinglong Su (X)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Institute of Traditional Chinese Medicine Resources Protection and Development, Anhui Academy of Chinese Medicine, Hefei, 230012, China.

Yingying Liu (Y)

College of Humanities and International Education Exchange, Anhui University of Chinese Medicine, Hefei, 230012, China.

Lu Han (L)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.

Zhaojian Wang (Z)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Institute of Traditional Chinese Medicine Resources Protection and Development, Anhui Academy of Chinese Medicine, Hefei, 230012, China.

Mengyang Cao (M)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Institute of Traditional Chinese Medicine Resources Protection and Development, Anhui Academy of Chinese Medicine, Hefei, 230012, China.

Liping Wu (L)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.

Weimin Jiang (W)

College of Life Sciences and Environment, Hengyang Normal University, Hengyang, 421008, Hunan, China.

Fei Meng (F)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.

Xiaohu Guo (X)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.

Nianjun Yu (N)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.

Shuangying Gui (S)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Anhui Province Key Laboratory of Pharmaceutical Preparation Technology and Application, Anhui University of Chinese Medicine, Hefei, 230012, China.

Shihai Xing (S)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Institute of Traditional Chinese Medicine Resources Protection and Development, Anhui Academy of Chinese Medicine, Hefei, 230012, China.
Anhui Province Key Laboratory of Research and Development of Chinese Medicine, Hefei, 230012, China. xshshihai@163.com.

Daiyin Peng (D)

School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, China.
Institute of Traditional Chinese Medicine Resources Protection and Development, Anhui Academy of Chinese Medicine, Hefei, 230012, China.
Synergetic Innovation Center of Anhui Authentic Chinese Medicine Quality Improvement, Hefei, 230038, China. pengdy@ahtcm.edu.cn.

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Classifications MeSH