Nano-sized carriers for capsaicinoids with topic analgesic and anti-inflammatory effects.

Analgesics / pharmacology Anti-Inflammatory Agents / pharmacology Capsaicin Capsicum Catechols
Capsaicin Nano-liposomes Nanocapsules Nanoemulsions Nanostructured lipid carriers Solid-lipid nanoparticles TRPV1

Journal

Journal of biotechnology
ISSN: 1873-4863
Titre abrégé: J Biotechnol
Pays: Netherlands
ID NLM: 8411927

Informations de publication

Date de publication:
10 Jun 2021
Historique:
received: 11 11 2020
revised: 05 04 2021
accepted: 22 04 2021
pubmed: 9 5 2021
medline: 25 9 2021
entrez: 8 5 2021
Statut: ppublish

Résumé

Capsaicinoids confer the pungency in chili peppers and are proven to contain many beneficial traits, among them analgesic and anti-inflammatory properties. Capsaicinoids produce a burning sensation when administered and have other secondary effects given their pungency. This is why many drug delivery vehicles have been tested to prove their efficacy in reducing the secondary effects of these compounds while still having its primary beneficial effects. There are many articles that talk about the formulation of drug delivery systems and their properties yet there is little information on the therapeutic effects of applying these drug delivery systems. This review is focused on studies' results that prove efficacy of capsaicinoids specially in those that use them in nano-sized drug delivery systems. Nano-sized carriers have been proven to reduce the secondary effects of capsaicinoids while improving the bioavailability, absorption, anti-inflammatory and analgesic properties of these compounds.

Identifiants

DOI: 10.1016/j.jbiotec.2021.04.009 PMID: 33964358
pubmed: 33964358
pii: S0168-1656(21)00114-0
doi: 10.1016/j.jbiotec.2021.04.009
pii:
doi:

Substances chimiques

Analgesics 0
Anti-Inflammatory Agents 0
Catechols 0
Capsaicin S07O44R1ZM

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

77-85

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Ana Emilia Nava-Ochoa (AE)

Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Centro de Biotecnología FEMSA, Eugenio Garza Sada 2501 Sur, C.P., 64849, Monterrey, N.L., Mexico.

Marilena Antunes-Ricardo (M)

Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Centro de Biotecnología FEMSA, Eugenio Garza Sada 2501 Sur, C.P., 64849, Monterrey, N.L., Mexico. Electronic address: marilena.antunes@tec.mx.

Daniel Guajardo-Flores (D)

Tecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Centro de Biotecnología FEMSA, Eugenio Garza Sada 2501 Sur, C.P., 64849, Monterrey, N.L., Mexico. Electronic address: danielgdo@tec.mx.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Analgésiques › Nano-sized carriers for capsaicinoids with...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-inflammatoires › Nano-sized carriers for capsaicinoids with...
questionsmedicales.fr › Lipides › Acides gras › Acides gras insaturés › Acides gras monoinsaturés › Capsaïcine › Nano-sized carriers for capsaicinoids with...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Solanales › Solanaceae › Capsicum › Nano-sized carriers for capsaicinoids with...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › Catéchols › Nano-sized carriers for capsaicinoids with...