Cardiovascular disease risks in younger versus older adult B-cell non-Hodgkin's lymphoma survivors.
Adult
Age Factors
Aged
Aged, 80 and over
Cancer Survivors
Cardiovascular Diseases
/ etiology
Female
Heart Disease Risk Factors
Heart Diseases
/ etiology
Heart Failure
/ etiology
Heart Valve Diseases
/ etiology
Humans
Hypotension
/ etiology
Lymphoma, B-Cell
/ complications
Male
Middle Aged
Myocarditis
/ etiology
Proportional Hazards Models
Registries
Rheumatic Heart Disease
/ etiology
Utah
Vascular Diseases
/ etiology
Young Adult
accelerated aging
cardiovascular disease
long-term health
non-Hodgkin's lymphoma
survivorship
Journal
Cancer medicine
ISSN: 2045-7634
Titre abrégé: Cancer Med
Pays: United States
ID NLM: 101595310
Informations de publication
Date de publication:
06 2021
06 2021
Historique:
revised:
24
02
2021
received:
11
11
2020
accepted:
03
04
2021
pubmed:
13
5
2021
medline:
25
12
2021
entrez:
12
5
2021
Statut:
ppublish
Résumé
Young cancer survivors may be at increased risk of early-onset chronic health conditions. The aim of this population-based study is to estimate cardiovascular disease (CVD) risk among younger versus older B-cell non-Hodgkin's lymphoma (B-NHL) survivors compared with their respective general population cohorts. B-NHL survivors diagnosed from 1997 to 2015 in the Utah Cancer Registry were matched with up to five cancer-free individuals on birth year, sex, and birth state, using the statewide Utah Population Database. Electronic medical records and statewide health care facility data were used to identify disease outcomes ≥5 years after cancer diagnosis. Cox Proportional Hazards models were used to estimate hazard ratios for B-NHL survivors diagnosed at <65 years and ≥65 years old. Younger B-NHL survivors had higher relative risks than older cancer survivors of chronic rheumatic disease of the heart valves (HR = 4.14, 99% CI = 2.17-7.89; P value Younger B-NHL survivors had higher risks than older B-NHL survivors of specific cardiovascular diseases compared to their respective general population cohorts.
Identifiants
pubmed: 33979029
doi: 10.1002/cam4.3934
pmc: PMC8209610
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
4117-4126Subventions
Organisme : NCI NIH HHS
ID : R21 CA185811
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002538
Pays : United States
Informations de copyright
© 2021 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.
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