Mode of action and efficacy of quinolinic acid for the control of Ceratocystis fimbriata on sweet potato.

Ceratocystis fimbriata antifungal activity ergosterol biosynthesis inhibitor quinolinic acid sweet potato

Journal

Pest management science
ISSN: 1526-4998
Titre abrégé: Pest Manag Sci
Pays: England
ID NLM: 100898744

Informations de publication

Date de publication:
Oct 2021
Historique:
revised: 27 03 2021
received: 01 11 2020
accepted: 04 06 2021
pubmed: 5 6 2021
medline: 4 9 2021
entrez: 4 6 2021
Statut: ppublish

Résumé

Ceratocystis fimbriata is a hazardous fungal pathogen able to cause black rot disease on sweet potato. The management of C. fimbriata strongly relies on the use of toxic fungicides, and there is a lack of efficient alternative strategies. The antifungal properties of quinolinic acid (QA) were studied for the first time, indicating that QA shows selective antifungal activity against C. fimbriata. QA inhibited completely the mycelial growth of C. fimbriata at less than 0.8 mg mL The first selective antifungal agent against C. fimbriata was discovered in this work, and showed suitable antifungal properties for the management of black rot disease. © 2021 Society of Chemical Industry.

Sections du résumé

BACKGROUND BACKGROUND
Ceratocystis fimbriata is a hazardous fungal pathogen able to cause black rot disease on sweet potato. The management of C. fimbriata strongly relies on the use of toxic fungicides, and there is a lack of efficient alternative strategies.
RESULTS RESULTS
The antifungal properties of quinolinic acid (QA) were studied for the first time, indicating that QA shows selective antifungal activity against C. fimbriata. QA inhibited completely the mycelial growth of C. fimbriata at less than 0.8 mg mL
CONCLUSIONS CONCLUSIONS
The first selective antifungal agent against C. fimbriata was discovered in this work, and showed suitable antifungal properties for the management of black rot disease. © 2021 Society of Chemical Industry.

Identifiants

pubmed: 34086397
doi: 10.1002/ps.6495
doi:

Substances chimiques

Quinolinic Acid F6F0HK1URN

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4564-4571

Subventions

Organisme : Innovation and Entrepreneurship Training Program for College Students in Jiangsu Province
ID : 201910304091Y
Organisme : Large Instruments Open Foundation of Nantong University
ID : KFJN2041
Organisme : Large Instruments Open Foundation of Nantong University
ID : KFJN2043
Organisme : Large Instruments Open Foundation of Nantong University
ID : KFJN2046
Organisme : Nantong Applied Research Program
ID : MS12017023-8
Organisme : National Natural Science Foundation of China
ID : 3201101306
Organisme : National Natural Science Foundation of China
ID : 81803407
Organisme : Natural Science Research Project of Jiangsu Higher Education Institutions
ID : 18KJB180023

Informations de copyright

© 2021 Society of Chemical Industry.

Références

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Auteurs

Ying Chen (Y)

School of Life Sciences, Nantong University, Nantong, China.

Yi-Dong Zhou (YD)

School of Life Sciences, Nantong University, Nantong, China.

Pablo Laborda (P)

Centro Nacional de Biotecnología, CSIC, Madrid, Spain.

Hai-Lin Wang (HL)

School of Life Sciences, Nantong University, Nantong, China.

Rui Wang (R)

School of Life Sciences, Nantong University, Nantong, China.

Xian Chen (X)

Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of Ministry of Science and Technology, Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China.

Feng-Quan Liu (FQ)

Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of Ministry of Science and Technology, Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Nanjing, China.

Dong-Jing Yang (DJ)

Xuzhou Institute of Agricultural Sciences in Xuhuai District, Sweet Potato Research Institute, Xuzhou, China.

Su-Yan Wang (SY)

School of Life Sciences, Nantong University, Nantong, China.

Xin-Chi Shi (XC)

School of Life Sciences, Nantong University, Nantong, China.

Pedro Laborda (P)

School of Life Sciences, Nantong University, Nantong, China.

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