Robotic system for magnetic resonance guided focused ultrasound ablation of abdominal cancer.
MRgFUS
abdominal cancer
kidney
liver
rabbit ablation
robotic device
Journal
The international journal of medical robotics + computer assisted surgery : MRCAS
ISSN: 1478-596X
Titre abrégé: Int J Med Robot
Pays: England
ID NLM: 101250764
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
revised:
07
06
2021
received:
09
03
2021
accepted:
08
06
2021
pubmed:
10
6
2021
medline:
4
9
2021
entrez:
9
6
2021
Statut:
ppublish
Résumé
A prototype robotic system that uses magnetic resonance guided focused ultrasound (MRgFUS) technology is presented. It features three degrees of freedom (DOF) and is intended for thermal ablation of abdominal cancer. The device is equipped with three identical transducers being offset between them, thus focussing at different depths in tissue. The efficacy and safety of the system in ablating rabbit liver and kidney was assessed, both in laboratory and magnetic resonance imaging (MRI) conditions. Despite these organs' challenging location, in situ coagulative necrosis of a tissue area was achieved. Heating of abdominal organs in rabbit was successfully monitored with MR thermometry. The MRgFUS system was proven successful in creating lesions in the abdominal area of rabbits. The outcomes of the study are promising for future translation of the technology to the clinic.
Sections du résumé
BACKGROUND
BACKGROUND
A prototype robotic system that uses magnetic resonance guided focused ultrasound (MRgFUS) technology is presented. It features three degrees of freedom (DOF) and is intended for thermal ablation of abdominal cancer.
METHODS
METHODS
The device is equipped with three identical transducers being offset between them, thus focussing at different depths in tissue. The efficacy and safety of the system in ablating rabbit liver and kidney was assessed, both in laboratory and magnetic resonance imaging (MRI) conditions.
RESULTS
RESULTS
Despite these organs' challenging location, in situ coagulative necrosis of a tissue area was achieved. Heating of abdominal organs in rabbit was successfully monitored with MR thermometry.
CONCLUSIONS
CONCLUSIONS
The MRgFUS system was proven successful in creating lesions in the abdominal area of rabbits. The outcomes of the study are promising for future translation of the technology to the clinic.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2299Subventions
Organisme : Cyprus Seeds
ID : ABLASONIC
Informations de copyright
© 2021 John Wiley & Sons Ltd.
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