Chemical linguistics: Reading the modified proteome.


Journal

Molecular cell
ISSN: 1097-4164
Titre abrégé: Mol Cell
Pays: United States
ID NLM: 9802571

Informations de publication

Date de publication:
17 06 2021
Historique:
entrez: 18 6 2021
pubmed: 19 6 2021
medline: 13 7 2021
Statut: ppublish

Résumé

In this issue of Molecular Cell, Lin et al. (2021) develop a tri-functional amino acid probe for the discovery and characterization of protein domains that sense or "read" protein post-translational modifications, a chemical tool that can facilitate our understanding of how signaling networks act at the molecular level.

Identifiants

pubmed: 34143967
pii: S1097-2765(21)00387-7
doi: 10.1016/j.molcel.2021.05.011
pmc: PMC8699185
mid: NIHMS1764143
pii:
doi:

Substances chimiques

Proteome 0

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

2501-2503

Subventions

Organisme : NIGMS NIH HHS
ID : R35 GM139569
Pays : United States

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests Or Gozani is a co-scientific founder and stockholder of EpiCypher, Inc., Athelas Therapeutics, Inc., and K36 Therapeutics, Inc.

Références

Chem Soc Rev. 2013 Apr 21;42(8):3289-301
pubmed: 23396550
Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8295-8300
pubmed: 30967505
Nat Struct Mol Biol. 2007 Nov;14(11):1025-1040
pubmed: 17984965
Nat Struct Mol Biol. 2012 Dec;19(12):1218-27
pubmed: 23211769
Mol Cell. 2017 Dec 7;68(5):1016-1016.e1
pubmed: 29220647
Nat Struct Mol Biol. 2019 Oct;26(10):880-889
pubmed: 31582846
Cell. 2010 Sep 17;142(6):967-80
pubmed: 20850016
Elife. 2014 Nov 04;3:
pubmed: 25369635
PLoS Comput Biol. 2015 Feb 18;11(2):e1004049
pubmed: 25692714
Mol Cell. 2021 Jun 17;81(12):2669-2681.e9
pubmed: 33894155

Auteurs

John P Coan (JP)

Department of Biology, Stanford University, Stanford, CA 94305, USA.

Shuo Liu (S)

Department of Biology, Stanford University, Stanford, CA 94305, USA.

Or Gozani (O)

Department of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: ogozani@stanford.edu.

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Classifications MeSH