Effectiveness of Brain Gaming in Older Adults With Cognitive Impairments: A Systematic Review and Meta-Analysis.
Alzheimer's disease
Brain gaming
cognitive training
dementia
mild cognitive impairment
Journal
Journal of the American Medical Directors Association
ISSN: 1538-9375
Titre abrégé: J Am Med Dir Assoc
Pays: United States
ID NLM: 100893243
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
received:
05
01
2021
revised:
17
05
2021
accepted:
19
05
2021
pubmed:
20
6
2021
medline:
15
12
2021
entrez:
19
6
2021
Statut:
ppublish
Résumé
This systematic review and meta-analysis evaluates the evidence from randomized clinical trials (RCTs) that designed brain gaming interventions to improve cognitive functions of older adults with cognitive impairments, including mild cognitive impairments and dementia. Systematic review and meta-analysis. N/A. N/A. Data sources-relevant randomized control trials (RCTs) were identified by a systematic search of databases including Medline, PubMed, PsycINFO, Embase, CINAHL, Web of Science, and Cochrane. RCTs were selected first based on title and abstract review and then on full-text review by independent reviewers using predefined eligibility criteria. Risk of bias (RoB) was assessed using the Cochrane RoB tool and funnel plots. The primary outcome variable was the composite score of global cognitive function. A total of 909 participants with mild cognitive impairment or dementia from 16 RCTs were included in the systematic review. The study quality was modest, and the RoB assessment showed bias in blinding the participants and personnel. Funnel plots showed no evidence of publication bias. The meta-analysis of 14 RCTs revealed no superior effect of brain gaming compared to other interventions on global cognitive function (pooled standardized mean difference = 0.08, 95% confidence interval -0.24, 0.41, P = .61, I The findings of this meta-analysis suggest that brain gaming compared with the control intervention does not show significant improvement in standardized tests of cognitive function. Because of considerable heterogeneity in sample size, gaming platform, cognitive status, study design, assessment tools, and training prescription, we cannot confidently refute the premise that brain gaming is an effective cognitive training approach for older adults with cognitive impairments. Recommendations for future research are included.
Identifiants
pubmed: 34146517
pii: S1525-8610(21)00488-6
doi: 10.1016/j.jamda.2021.05.022
pmc: PMC8628430
mid: NIHMS1750305
pii:
doi:
Types de publication
Journal Article
Meta-Analysis
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2281-2288.e5Subventions
Organisme : RRD VA
ID : I21 RX003015
Pays : United States
Organisme : RRD VA
ID : IK2 RX002938
Pays : United States
Organisme : NIA NIH HHS
ID : K01 AG058785
Pays : United States
Informations de copyright
Copyright © 2021 AMDA – The Society for Post-Acute and Long-Term Care Medicine. All rights reserved.
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