To ventilate or not to ventilate during bystander CPR - A EuReCa TWO analysis.


Journal

Resuscitation
ISSN: 1873-1570
Titre abrégé: Resuscitation
Pays: Ireland
ID NLM: 0332173

Informations de publication

Date de publication:
09 2021
Historique:
received: 02 12 2020
revised: 25 05 2021
accepted: 09 06 2021
pubmed: 20 6 2021
medline: 3 11 2021
entrez: 19 6 2021
Statut: ppublish

Résumé

Survival after out-of-hospital cardiac arrest (OHCA) is still low. For every minute without resuscitation the likelihood of survival decreases. One critical step is initiation of immediate, high quality cardiopulmonary resuscitation (CPR). The aim of this subgroup analysis of data collected for the European Registry of Cardiac Arrest Study number 2 (EuReCa TWO) was to investigate the association between OHCA survival and two types of bystander CPR namely: chest compression only CPR (CConly) and CPR with chest compressions and ventilations (FullCPR). In this subgroup analysis of EuReCa TWO, all patients who received bystander CPR were included. Outcomes were return of spontaneous circulation and survival to 30-days or hospital discharge. A multilevel binary logistic regression analysis with survival as the dependent variable was performed. A total of 5884 patients were included in the analysis, varying between countries from 21 to 1444. Survival was 320 (8%) in the CConly group and 174 (13%) in the FullCPR group. After adjustment for age, sex, location, rhythm, cause, time to scene, witnessed collapse and country, patients who received FullCPR had a significantly higher survival rate when compared to those who received CConly (adjusted odds ration 1.46, 95% confidence interval 1.17-1.83). In this analysis, FullCPR was associated with higher survival compared to CConly. Guidelines should continue to emphasise the importance of compressions and ventilations during resuscitation for patients who suffer OHCA and CPR courses should continue to teach both.

Sections du résumé

BACKGROUND
Survival after out-of-hospital cardiac arrest (OHCA) is still low. For every minute without resuscitation the likelihood of survival decreases. One critical step is initiation of immediate, high quality cardiopulmonary resuscitation (CPR). The aim of this subgroup analysis of data collected for the European Registry of Cardiac Arrest Study number 2 (EuReCa TWO) was to investigate the association between OHCA survival and two types of bystander CPR namely: chest compression only CPR (CConly) and CPR with chest compressions and ventilations (FullCPR).
METHOD
In this subgroup analysis of EuReCa TWO, all patients who received bystander CPR were included. Outcomes were return of spontaneous circulation and survival to 30-days or hospital discharge. A multilevel binary logistic regression analysis with survival as the dependent variable was performed.
RESULTS
A total of 5884 patients were included in the analysis, varying between countries from 21 to 1444. Survival was 320 (8%) in the CConly group and 174 (13%) in the FullCPR group. After adjustment for age, sex, location, rhythm, cause, time to scene, witnessed collapse and country, patients who received FullCPR had a significantly higher survival rate when compared to those who received CConly (adjusted odds ration 1.46, 95% confidence interval 1.17-1.83).
CONCLUSION
In this analysis, FullCPR was associated with higher survival compared to CConly. Guidelines should continue to emphasise the importance of compressions and ventilations during resuscitation for patients who suffer OHCA and CPR courses should continue to teach both.

Identifiants

pubmed: 34146622
pii: S0300-9572(21)00229-X
doi: 10.1016/j.resuscitation.2021.06.006
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

101-109

Investigateurs

Maximilian Moertl (M)
Pierre Mols (P)
Hajriz Alihodžić (H)
Irzal Hadžibegović (I)
Marios Ioannides (M)
Anatolij Truhlář (A)
Mads Wissenberg (M)
Ari Salo (A)
Josephine Escutnaire (J)
Nikolaos Nikolaou (N)
Eniko Nagy (E)
Bergthor Steinn Jonsson (BS)
Peter Wright (P)
Federico Semeraro (F)
Carlo Clarens (C)
Steffie Beesems (S)
Grzegorz Cebula (G)
Vitor H Correia (VH)
Diana Cimpoesu (D)
Violetta Raffay (V)
Stefan Trenkler (S)
Andrej Markota (A)
Anneli Strömsöe (A)
Roman Burkart (R)
Scott Booth (S)
Michael Baubin (M)
Adolf Schinnerl (A)
Gerhard Prause (G)
Thomas Tschoellitsch (T)
Helmut Trimmel (H)
Rene Belz (R)
Wolfgang Fleischmann (W)
Magali Bartiaux (M)
Koenraad Monsieurs (K)
Stephan Wilmin (S)
Mathias Faniel (M)
Marie Vanhove (M)
Pascale Lievens (P)
Dominique Biarent (D)
Marc Van Nuffelen (M)
Ives Hubloue (I)
Jean-Marie Jacques (JM)
Michèle Yerna (M)
Robert Leach (R)
Mathieu Jeanmaire (M)
Paule Denoël (P)
Frank Van Trimpont (F)
Francis Desmet (F)
Louise Delhaye (L)
Vincent Van Belleghem (V)
Ken Dewitte (K)
Musa Abbasi (M)
Simon Scheyltjens (S)
Olivier Vermylen (O)
Diane de Longueville (D)
Stéphane Debaize (S)
Silvija Hunyadi Antičević (SH)
Slobodanka Keleuva (S)
Milan Lazarević (M)
Radmila Majhen Ujević (RM)
Gordana Antić Šego (GA)
Branka Bardak (B)
Domagoj Mišković (D)
Monika Praunová (M)
Ondřej Franěk (O)
Jaroslav Kratochvíl (J)
Jan Přikryl (J)
Roman Sýkora (R)
Tomáš Vaňatka (T)
Marek Vašák (M)
Petr Jaššo (P)
Petr Šmejkal (P)
Otomar Kušička (O)
Robin Šín (R)
Eva Smržová (E)
Dorián Pfeifer (D)
Heini Harve-Rytsälä (H)
Pamela Hiltunen (P)
Peter Holmström (P)
Timo Iirola (T)
Katja Jokela (K)
Hetti Kirves (H)
Pekka Korvenoja (P)
Markku Kuisma (M)
Jukka Laine (J)
Markus Lyyra (M)
Sami Länkimäki (S)
Petra Portaankorva (P)
Lasse Raatiniemi (L)
Marko Sainio (M)
Piritta Setälä (P)
Tuukka Toivonen (T)
Jan Uotinen (J)
Jukka Vaahersalo (J)
Taneli Väyrynen (T)
David Hamdan (D)
Jean-Marc Agostinucci (JM)
Josephine Escutnaire (J)
Fabienne Branche (F)
François Revaux (F)
Sébastien Jonquet (S)
Richard Loubert (R)
Marion Boursier (M)
Bruno Simonnet (B)
Jean-Charles Morel (JC)
Steven Lagadec (S)
Aurélie Avondo (A)
Emilie Gelin (E)
Emanuel Morel-Maréchal (E)
Cécile Ursat (C)
Laurent Villain-Coquet (L)
Marc Fournier (M)
Romain Tabary (R)
Philippe Le Pimpec (P)
Delphine Hugenschmitt (D)
Diego Abarrategui (D)
Romain Blondet (R)
Aurélie Arnaud (A)
Sonia Sadoune (S)
Julien Segard (J)
Sophie Narcisse (S)
Mélanie Laot (M)
Thomas Pernot (T)
Hubert Courcoux (H)
Coralie Chassin (C)
Benoît Jardel (B)
Jeanne Picart (J)
Franck Garden Brèche (FG)
Pierre-Alban Guenier (PA)
Renaud Getti (R)
Alexandre Jeziorny (A)
Antoine Leroy (A)
Carine Vanderstraeten (C)
Sébastien Dussoulier (S)
Attila Haja (A)
Dániel Németh (D)
Andrea Válint (A)
Eniko Nagy (E)
Gábor Csató (G)
Gerda Lóczi (G)
Péter Vörös (P)
Zsuzsanna Németh (Z)
Ferenc Molnár (F)
Ferenc Nagy (F)
Henrietta Kádár (H)
Julia Duda (J)
Justyna Tęczar (J)
Sylwia Dul (S)
Grażyna Świtacz (G)
Andrzej Raczynski (A)
Zlatko Fiser (Z)
Zlatko Babic (Z)
Aleksandra Opacic (A)
Kornelija Jaksic Horvat (KJ)
Snezana Vukelic (S)
Jelena Tijanic (J)
Dusan Milenkovic (D)
Sasa Milic (S)
Deze Babinski (D)
Cedomir Boskovic (C)
Jovanka Koprivica (J)
Erika Terek (E)
Goran Provci (G)
Dragana Jovic Zvijer (DJ)
Ľubica Bajerovská (Ľ)
Miroslav Chabroň (M)
Danka Pražienková (D)
Renáta Kratochvílová (R)
Radoslav Burian (R)
Martin Dobrík (M)
Juraj Patráš (J)
Vladimír Šteflík (V)
Peter Androvič (P)
František Mičáň (F)
Božena Horáňová (B)
Július Pavčo (J)
Monika Grochová (M)
Táňa Bulíková (T)
Rok Maček (R)
Matej Rubelli Furman (MR)
Samo Podhostnik (S)
Miha Oman (M)
Klemen Lipovšek (K)
Špela Baznik (Š)
Jurica Ferenčina (J)
Matej Strnad (M)
Edith Žižek (E)
Miha Kodela (M)
Alenka Antolinc Košat (AA)
Nina Lotrič (N)
Jonny Lindqvist (J)
Remy Stieglis (R)
Anja Radstok (A)

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Jan Wnent (J)

University Hospital Schleswig-Holstein, Institute for Emergency Medicine, Kiel, Germany; University Hospital Schleswig-Holstein, Department of Anaesthesiology and Intensive Care Medicine, Kiel, Germany; University of Namibia, School of Medicine, Windhoek, Namibia. Electronic address: Jan.wnent@uksh.de.

Ingvild Tjelmeland (I)

University Hospital Schleswig-Holstein, Institute for Emergency Medicine, Kiel, Germany; Division of Prehospital Services, Oslo University Hospital, Norway; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Norway.

Rolf Lefering (R)

Institute for Research in Operative Medicine (IFOM), Faculty of Health, University Witten/Herdecke, Cologne, Germany.

Rudolph W Koster (RW)

Department of Cardiology, Amsterdam UMC, Location Academic Medical Center, Amsterdam, The Netherlands.

Holger Maurer (H)

University Hospital Schleswig-Holstein, Department of Anaesthesiology and Intensive Care Medicine, Lübeck, Germany.

Siobhán Masterson (S)

National Ambulance Service and National University of Ireland Galway (on behalf of the Out-of-Hospital Cardiac Arrest Register (OHCAR)), Ireland.

Johan Herlitz (J)

Prehospen-Centre for Prehospital Research, Faculty of Caring Science, Work-Life and Social Welfare, University of Borås, Borås, Sweden.

Bernd W Böttiger (BW)

Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Cologne, Germany; European Resuscitation Council, Niel, Belgium.

Fernando Rosell Ortiz (FR)

Servicio de Urgencias y Emergencias 061 de La Rioja, Spain.

Gavin D Perkins (GD)

Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, United Kingdom; University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom; European Resuscitation Council, Niel, Belgium.

Leo Bossaert (L)

University of Antwerp, Antwerp, Belgium; European Resuscitation Council, Niel, Belgium.

Maximilian Moertl (M)

Medical University of Innsbruck, Department of Anaesthesia and Intensive Care, Innsbruck, Austria.

Pierre Mols (P)

Service des Urgences et du SMUR, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Belgium.

Irzal Hadžibegović (I)

University Hospital Dubrava Zagreb, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University Osijek, Croatia.

Anatolij Truhlář (A)

Emergency Medical Services of the Hradec Králové Region, Hradec Králové, Czech Republic; Department of Anaesthesiology and Intensive Care Medicine, Charles University Prague, Faculty of Medicine Hradec Králové, University Hospital Hradec Králové, Czech Republic.

Ari Salo (A)

Department of Emergency Medicine and Services, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Valentine Baert (V)

Univ. Lille, CHU Lille, ULR 2694 - METRICS: Évaluation des Technologies de Santé et des Pratiques Médicales, F-59000 Lille, France.

Eniko Nagy (E)

Hungarian Resuscitation Council.

Grzegorz Cebula (G)

Jagiellonian University Medical College, Department of Medical Education, Poland.

Violetta Raffay (V)

Serbian Resuscitation Council, Novi Sad, Serbia; European University Cyprus, School of Medicine, Nicosia, Cyprus.

Stefan Trenkler (S)

P. J. Safarik University, Medical Faculty, L. Pasteur University Hospital, Department of Anaesthesiology and Intensive Medicine, Kosice, Slovakia.

Andrej Markota (A)

Medical Intensive Care Unit, University Medical Centre Maribor, Maribor, Slovenia; Slovenian Resuscitation Council, Slovenian Society for Emergency Medicine, Ljubljana, Slovenia.

Anneli Strömsöe (A)

School of Education, Health and Social Studies, Dalarna University S-79188 Falun, Sweden; Centre for Clinical Research Dalarna, Uppsala University S-79182 Falun, Sweden; Department of Prehospital Care, Region of Dalarna, S-79129 Falun, Sweden.

Jan-Thorsten Gräsner (JT)

University Hospital Schleswig-Holstein, Institute for Emergency Medicine, Kiel, Germany; University Hospital Schleswig-Holstein, Department of Anaesthesiology and Intensive Care Medicine, Kiel, Germany; European Resuscitation Council, Niel, Belgium.

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