Predicting the duration of sickness absence due to knee osteoarthritis: a prognostic model developed in a population-based cohort in Sweden.

Duration Knee osteoarthritis Prediction Sick-leave Sickness absence

Journal

BMC musculoskeletal disorders
ISSN: 1471-2474
Titre abrégé: BMC Musculoskelet Disord
Pays: England
ID NLM: 100968565

Informations de publication

Date de publication:
02 Jul 2021
Historique:
received: 16 11 2020
accepted: 25 05 2021
entrez: 3 7 2021
pubmed: 4 7 2021
medline: 7 7 2021
Statut: epublish

Résumé

Predicting the duration of sickness absence (SA) among sickness absent patients is a task many sickness certifying physicians as well as social insurance officers struggle with. Our aim was to develop a prediction model for prognosticating the duration of SA due to knee osteoarthritis. A population-based prospective study of SA spells was conducted using comprehensive microdata linked from five Swedish nationwide registers. All 12,098 new SA spells > 14 days due to knee osteoarthritis in 1/1 2010 through 30/6 2012 were included for individuals 18-64 years. The data was split into a development dataset (70 %, n Of all SA spells, 53 % were > 90 days and 3 % >365 days. Factors included in the final model were age, sex, geographical region, extent of sickness absence, previous sickness absence, history of specialized outpatient healthcare and/or inpatient healthcare, employment status, and educational level. The model was well calibrated. Overall, discrimination was poor (c = 0.53, 95 % confidence interval (CI) 0.52-0.54). For predicting SA > 90 days, discrimination as measured by AUC was 0.63 (95 % CI 0.61-0.65), for > 180 days, 0.69 (95 % CI 0.65-0.71), and for SA > 365 days, AUC was 0.75 (95 % CI 0.72-0.78). It was possible to predict patients at risk of long-term SA (> 180 days) with acceptable precision. However, the prediction of duration of SA spells due to knee osteoarthritis has room for improvement.

Sections du résumé

BACKGROUND BACKGROUND
Predicting the duration of sickness absence (SA) among sickness absent patients is a task many sickness certifying physicians as well as social insurance officers struggle with. Our aim was to develop a prediction model for prognosticating the duration of SA due to knee osteoarthritis.
METHODS METHODS
A population-based prospective study of SA spells was conducted using comprehensive microdata linked from five Swedish nationwide registers. All 12,098 new SA spells > 14 days due to knee osteoarthritis in 1/1 2010 through 30/6 2012 were included for individuals 18-64 years. The data was split into a development dataset (70 %, n
RESULTS RESULTS
Of all SA spells, 53 % were > 90 days and 3 % >365 days. Factors included in the final model were age, sex, geographical region, extent of sickness absence, previous sickness absence, history of specialized outpatient healthcare and/or inpatient healthcare, employment status, and educational level. The model was well calibrated. Overall, discrimination was poor (c = 0.53, 95 % confidence interval (CI) 0.52-0.54). For predicting SA > 90 days, discrimination as measured by AUC was 0.63 (95 % CI 0.61-0.65), for > 180 days, 0.69 (95 % CI 0.65-0.71), and for SA > 365 days, AUC was 0.75 (95 % CI 0.72-0.78).
CONCLUSION CONCLUSIONS
It was possible to predict patients at risk of long-term SA (> 180 days) with acceptable precision. However, the prediction of duration of SA spells due to knee osteoarthritis has room for improvement.

Identifiants

pubmed: 34215239
doi: 10.1186/s12891-021-04400-8
pii: 10.1186/s12891-021-04400-8
pmc: PMC8254363
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

603

Subventions

Organisme : Forskningsrådet om Hälsa, Arbetsliv och Välfärd
ID : 2007-1762

Références

Fam Pract. 2004 Apr;21(2):192-8
pubmed: 15020391
Stat Med. 2011 May 10;30(10):1105-17
pubmed: 21484848
BMJ Open. 2011 Dec 20;1(2):e000303
pubmed: 22189350
BMC Musculoskelet Disord. 2014 May 24;15:176
pubmed: 24886568
Dtsch Arztebl Int. 2010 Mar;107(9):152-62
pubmed: 20305774
Scand J Public Health. 2019 Feb;47(1):53-60
pubmed: 29576011
Best Pract Res Clin Rheumatol. 2014 Feb;28(1):5-15
pubmed: 24792942
Osteoarthritis Cartilage. 2015 Apr;23(4):507-15
pubmed: 25447976
Acta Orthop. 2018 Apr;89(2):177-183
pubmed: 29160139
Pharmacoepidemiol Drug Saf. 2007 Jul;16(7):726-35
pubmed: 16897791
Scand J Prim Health Care. 2014 Jun;32(2):73-7
pubmed: 24939740
Int J Qual Health Care. 2018 Jul 1;30(6):429-436
pubmed: 29590398
Arthritis Res Ther. 2015 Jun 08;17:152
pubmed: 26050740
BMC Public Health. 2010 Dec 06;10:752
pubmed: 21129227
Eur J Gen Pract. 2012 Dec;18(4):219-28
pubmed: 23205966
BMC Bioinformatics. 2011 Mar 17;12:77
pubmed: 21414208
Eur J Epidemiol. 2017 Sep;32(9):765-773
pubmed: 28983736
Scand J Public Health Suppl. 2004;63:12-30
pubmed: 15513650
BMC Public Health. 2007 Oct 02;7:273
pubmed: 17910746
Rheum Dis Clin North Am. 2013 Feb;39(1):1-19
pubmed: 23312408
BMJ Open. 2019 Aug 27;9(8):e030054
pubmed: 31462481
Environ Int. 2021 May;150:106349
pubmed: 33546919
BMC Public Health. 2004 Oct 12;4:46
pubmed: 15476563
Eur J Epidemiol. 2016 Feb;31(2):125-36
pubmed: 26769609
Ann Rheum Dis. 2013 Mar;72(3):401-5
pubmed: 22679305
Scand J Work Environ Health. 2018 May 1;44(3):274-282
pubmed: 29363714
Acta Orthop. 2020 Dec;91(6):717-723
pubmed: 32878525
BMC Musculoskelet Disord. 2019 May 7;20(1):196
pubmed: 31064359
Occup Med (Lond). 2012 Dec;62(8):648-50
pubmed: 23012345
BMC Public Health. 2011 Jun 09;11:450
pubmed: 21658213

Auteurs

Johanna Holm (J)

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 77, Stockholm, Sweden.

Paolo Frumento (P)

Department of Political Sciences, University of Pisa, Via F. Serafini 3, 56126, Pisa, Italy.

Gino Almondo (G)

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 77, Stockholm, Sweden.

Katalin Gémes (K)

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 77, Stockholm, Sweden.

Matteo Bottai (M)

Division of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77, Stockholm, Sweden.

Kristina Alexanderson (K)

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 77, Stockholm, Sweden.

Emilie Friberg (E)

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 77, Stockholm, Sweden.

Kristin Farrants (K)

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 77, Stockholm, Sweden. kristin.farrants@ki.se.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH