The Impact of IDH1 Mutation and MGMT Promoter Methylation on Recurrence-Free Interval in Glioblastoma Patients Treated With Radiotherapy and Chemotherapeutic Agents.
Biomarkers, Tumor
/ genetics
Brain Neoplasms
/ genetics
Chemoradiotherapy
/ mortality
DNA Methylation
DNA Modification Methylases
/ genetics
DNA Repair Enzymes
/ genetics
Female
Follow-Up Studies
Gene Expression Regulation, Neoplastic
Glioblastoma
/ genetics
Humans
Isocitrate Dehydrogenase
/ genetics
Male
Middle Aged
Neoplasm Recurrence, Local
/ genetics
Prognosis
Promoter Regions, Genetic
Survival Rate
Tumor Suppressor Proteins
/ genetics
IDH1 mutation
MGMT promoter methylation
chemotherapy
glioblastoma
radiotherapy
Journal
Pathology oncology research : POR
ISSN: 1532-2807
Titre abrégé: Pathol Oncol Res
Pays: Switzerland
ID NLM: 9706087
Informations de publication
Date de publication:
2021
2021
Historique:
received:
12
02
2021
accepted:
07
04
2021
entrez:
14
7
2021
pubmed:
15
7
2021
medline:
4
1
2022
Statut:
epublish
Résumé
The aim of this study is to investigate the relationship between isocitrate dehydrogenase-1 (
Identifiants
pubmed: 34257620
doi: 10.3389/pore.2021.1609778
pii: 1609778
pmc: PMC8262235
doi:
Substances chimiques
Biomarkers, Tumor
0
Tumor Suppressor Proteins
0
Isocitrate Dehydrogenase
EC 1.1.1.41
IDH1 protein, human
EC 1.1.1.42.
DNA Modification Methylases
EC 2.1.1.-
MGMT protein, human
EC 2.1.1.63
DNA Repair Enzymes
EC 6.5.1.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1609778Informations de copyright
Copyright © 2021 Kurdi, Shafique Butt, Baeesa, Alghamdi, Maghrabi, Bardeesi, Saeedi, Al-Sinani, Alghanmi, Bari, Samkari and Lary.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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