Cytokine storm syndrome in a young patient with cystic fibrosis.

hemophagocytic lymphohistiocytosis macrophage activation syndrome multisystem inflammatory syndrome related to SARS CoV2

Journal

Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590

Informations de publication

Date de publication:
10 2021
Historique:
revised: 06 07 2021
received: 16 06 2021
accepted: 11 07 2021
pubmed: 23 7 2021
medline: 15 12 2021
entrez: 22 7 2021
Statut: ppublish

Résumé

We report the case of a patient with cystic fibrosis (CF) presenting with a full-blown cytokine storm syndrome probably triggered by infection. This condition is rare and the diagnosis can be particularly difficult in patients with a complex chronic disease such as CF. However, timely recognition and appropriate treatment in the early stages are key to avoiding a potentially fatal course.

Identifiants

pubmed: 34293253
doi: 10.1002/ppul.25579
doi:

Types de publication

Case Reports Letter

Langues

eng

Sous-ensembles de citation

IM

Pagination

3435-3437

Informations de copyright

© 2021 Wiley Periodicals LLC.

Références

Fajgenbaum DC, June CH. Cytokine storm. N Engl J Med. 2020;383(23):2255-2273.
Casciaro R, Cresta F, Favilli F, Naselli A, De Alessandri A, Minicucci L. Macrophage activation syndrome induced by A/H1N1 influenza in cystic fibrosis. Pediatr Pulmonol. 2014;49(2):E10-E12.
Şişmanlar Eyüboğlu T, Aslan AT, Ramaslı Gursoy T, et al. Macrophage activation syndrome due to Nocardia spp in a pediatric patient with cystic fibrosis. Pediatr Pulmonol. 2019;54(4):E10-E12.
Radia T, Williams N, Agrawal P, et al. Multi-system inflammatory syndrome in children & adolescents (MIS-C): a systematic review of clinical features and presentation. Paediatr Respir Rev. 2020;38(2):51-57.
Ravelli A, Minoia F, Davì S, et al. Classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation collaborative initiative. Arthritis Rheumatol. 2016;68(3):566-576. https://pubmed.ncbi.nlm.nih.gov/26314788/

Auteurs

Valeria Daccò (V)

Cystic Fibrosis Regional Reference Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Chiara Rosazza (C)

Cystic Fibrosis Regional Reference Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Anna Malfitano (A)

Cystic Fibrosis Regional Reference Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Calogero S Sciarrabba (CS)

Cystic Fibrosis Regional Reference Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Francesca Minoia (F)

Pediatric Rheumatology, Medium Intensity Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Giovanni Filocamo (G)

Pediatric Rheumatology, Medium Intensity Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Carla Colombo (C)

Cystic Fibrosis Regional Reference Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

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