Impact of specific serotonin receptor modulation on behavioral flexibility.
Behavioral flexibility
Reversal learning
Serotonin receptor
Journal
Pharmacology, biochemistry, and behavior
ISSN: 1873-5177
Titre abrégé: Pharmacol Biochem Behav
Pays: United States
ID NLM: 0367050
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
received:
29
09
2020
revised:
06
07
2021
accepted:
09
07
2021
pubmed:
28
7
2021
medline:
23
2
2022
entrez:
27
7
2021
Statut:
ppublish
Résumé
Serotonin (5-HT) is known to play a critical role in regulation of essential neural processes, whereas more recent research highlights serotonin's modulatory effects on cognition and executive functioning. Current examinations have identified specific serotonin receptors for their direct impact on behavioral flexibility. Providing definitive evidence for the impact of specific receptor targets on behavioral flexibility is difficult, due to the range of behavioral tests used. Due to limited studies and the sheer amount of different serotonin receptor targets, beginning to bring these studies together is important for the field. Our current review of the literature aims to differentiate how modulation of specific 5-HT receptors affects behavioral flexibility. Although more studies have examined 5-HT
Identifiants
pubmed: 34314738
pii: S0091-3057(21)00142-8
doi: 10.1016/j.pbb.2021.173243
pmc: PMC8429145
mid: NIHMS1732827
pii:
doi:
Substances chimiques
Receptor, Serotonin, 5-HT2A
0
Receptor, Serotonin, 5-HT2C
0
Receptors, Serotonin
0
Serotonin
333DO1RDJY
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
173243Subventions
Organisme : NIGMS NIH HHS
ID : T34 GM136467
Pays : United States
Informations de copyright
Published by Elsevier Inc.
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