The Essential Frailty Toolset in Older Adults Undergoing Coronary Artery Bypass Surgery.
Aged
Comorbidity
Coronary Artery Bypass
/ adverse effects
Coronary Disease
/ epidemiology
Elective Surgical Procedures
/ methods
Emergency Medical Services
/ methods
Female
Frailty
/ diagnosis
Functional Status
Geriatric Assessment
/ methods
Hemoglobins
/ analysis
Humans
Male
Mental Status and Dementia Tests
Mortality
Prognosis
Risk Adjustment
/ methods
Serum Albumin
/ analysis
coronary artery bypass surgery
frailty
mortality
Journal
Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524
Informations de publication
Date de publication:
03 08 2021
03 08 2021
Historique:
pubmed:
29
7
2021
medline:
25
2
2023
entrez:
28
7
2021
Statut:
ppublish
Résumé
Background The Essential Frailty Toolset (EFT) was shown to be easy to use and predictive of adverse events in patients undergoing aortic valve replacement procedures. The objective of this study was to evaluate the EFT in patients undergoing coronary artery bypass grafting procedures. Methods and Results The McGill Frailty Registry prospectively included patients ≥60 years of age undergoing urgent or elective isolated coronary artery bypass grafting between 2011 and 2018 at 2 hospitals. The preoperative EFT was scored 0 to 5 points as a function of timed chair rises, Mini-Mental Status Examination, serum albumin, and hemoglobin. The primary outcome was all-cause mortality assessed by Cox proportional hazards regression. The cohort consisted of 500 patients with a mean age of 71.4 ± 6.4 years, of which 27% presented with acute coronary syndromes requiring urgent surgery. The mean EFT was 1.3 ± 1.1 points, 132 (26%) were nonfrail, 298 (60%) were prefrail, and 70 (14%) were frail. Over a median follow-up of 4.0 years, 78 deaths were observed. In nonfrail, prefrail, and frail patients, survival at 1 year was 98%, 95%, and 91%, and at 5 years was 89%, 83%, and 63% (
Identifiants
pubmed: 34315236
doi: 10.1161/JAHA.120.020219
pmc: PMC8475706
doi:
Substances chimiques
Hemoglobins
0
Serum Albumin
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e020219Subventions
Organisme : CIHR
Pays : Canada
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