ADP-ribosyltransferases, an update on function and nomenclature.

ADP Ribose Transferases / genetics Protein Biosynthesis Adenosine Diphosphate Ribose Adenosine Diphosphate
ADP-ribosylation MARylation PARP PARylation posttranslational modification

Journal

The FEBS journal
ISSN: 1742-4658
Titre abrégé: FEBS J
Pays: England
ID NLM: 101229646

Informations de publication

Date de publication:
12 2022
Historique:
revised: 23 07 2021
received: 03 06 2021
accepted: 27 07 2021
pubmed: 30 7 2021
medline: 15 12 2022
entrez: 29 7 2021
Statut: ppublish

Résumé

ADP-ribosylation, a modification of proteins, nucleic acids, and metabolites, confers broad functions, including roles in stress responses elicited, for example, by DNA damage and viral infection and is involved in intra- and extracellular signaling, chromatin and transcriptional regulation, protein biosynthesis, and cell death. ADP-ribosylation is catalyzed by ADP-ribosyltransferases (ARTs), which transfer ADP-ribose from NAD

Identifiants

DOI: 10.1111/febs.16142 PMID: 34323016 PMC: PMC9027952
pubmed: 34323016
doi: 10.1111/febs.16142
pmc: PMC9027952
mid: NIHMS1793355
doi:

Substances chimiques

ADP Ribose Transferases EC 2.4.2.-
Adenosine Diphosphate Ribose 20762-30-5
Adenosine Diphosphate 61D2G4IYVH

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Intramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

7399-7410

Subventions

Organisme : NIGMS NIH HHS
ID : P20 GM113117
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM133633
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM138029
Pays : United States

Informations de copyright

© 2021 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

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Auteurs

Bernhard Lüscher (B)

Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Germany.
ORCID: 0000-0002-9622-8709

Ivan Ahel (I)

Sir William Dunn School of Pathology, University of Oxford, UK.
ORCID: 0000-0002-9446-3756

Matthias Altmeyer (M)

Department of Molecular Mechanisms of Disease, University of Zurich, Switzerland.

Alan Ashworth (A)

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA.

Peter Bai (P)

Department of Medical Chemistry, Faculty of Medicine, University of Debrecen, Hungary.

Paul Chang (P)

ARase Therapeutics, Cambridge, MA, USA.

Michael Cohen (M)

Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, OR, USA.

Daniela Corda (D)

Department of Biomedical Sciences, National Research Council, Rome, Italy.

Françoise Dantzer (F)

CNRS, BSC-UMR7242, Illkirch, France.

Matthew D Daugherty (MD)

Division of Biological Sciences, University of California San Diego, La Jolla, CA, USA.

Ted M Dawson (TM)

Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Valina L Dawson (VL)

Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Sebastian Deindl (S)

Department of Cell and Molecular Biology, Uppsala University, Sweden.

Anthony R Fehr (AR)

Department of Molecular Biosciences, The University of Kansas, Lawrence, KS, USA.

Karla L H Feijs (KLH)

Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Germany.

Dmitri V Filippov (DV)

Leiden Institute of Chemistry, Leiden University, The Netherlands.

Jean-Philippe Gagné (JP)

Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Quebec City, QC, Canada.

Giovanna Grimaldi (G)

National Research Council, Naples, Italy.

Sebastian Guettler (S)

Divisions of Structural Biology and Cancer Biology, The Institute of Cancer Research (ICR), London, UK.

Nicolas C Hoch (NC)

Department of Biochemistry, University of São Paulo, Brazil.

Michael O Hottiger (MO)

Department of Molecular Mechanisms of Disease, University of Zurich, Switzerland.

Patricia Korn (P)

Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Germany.

W Lee Kraus (WL)

Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Andreas Ladurner (A)

Department of Physiological Chemistry, Ludwig-Maximilians-University of Munich, Planegg-Martinsried, Germany.

Lari Lehtiö (L)

Faculty of Biochemistry and Molecular Medicine & Biocenter Oulu, University of Oulu, Finland.

Anthony K L Leung (AKL)

Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Christopher J Lord (CJ)

CRUK Gene Function Laboratory, The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK.

Aswin Mangerich (A)

Department of Biology, University of Konstanz, Germany.

Ivan Matic (I)

Max Planck Institute for Biology of Ageing, Cologne, Germany.
Cologne Excellence Cluster for Stress Responses in Ageing-Associated Diseases (CECAD), University of Cologne, Germany.

Jason Matthews (J)

Institute of Basic Medical Sciences, University of Oslo, Norway.

George-Lucian Moldovan (GL)

Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA, USA.

Joel Moss (J)

National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.

Gioacchino Natoli (G)

Department of Experimental Oncology, European Institute of Oncology (IEO), Milan, Italy.

Michael L Nielsen (ML)

Proteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

Mario Niepel (M)

Ribon Therapeutics, Cambridge, MA, USA.
ORCID: 0000-0003-1415-6295

Friedrich Nolte (F)

Institut für Immunologie, Universitätsklinikum Hamburg-Eppendorf, Germany.

John Pascal (J)

Biochemistry and Molecular Medicine, Université de Montréal, Canada.

Bryce M Paschal (BM)

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA, USA.

Krzysztof Pawłowski (K)

Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Guy G Poirier (GG)

Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medicine, Laval University, Quebec City, QC, Canada.

Susan Smith (S)

Department of Pathology, Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, NY, USA.

Gyula Timinszky (G)

Lendület Laboratory of DNA Damage and Nuclear Dynamics, Institute of Genetics, Biological Research Centre, Eötvös Loránd Research Network (ELKH), Szeged, Hungary.

Zhao-Qi Wang (ZQ)

Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena, Germany.
Faculty of Biological Sciences, Friedrich-Schiller University of Jena, Germany.

José Yélamos (J)

Cancer Research Program, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.

Xiaochun Yu (X)

School of Life Sciences, Westlake University, Hangzhou, China.

Roko Zaja (R)

Institute of Biochemistry and Molecular Biology, RWTH Aachen University, Germany.

Mathias Ziegler (M)

Department of Biomedicine, University of Bergen, Norway.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Glycosyltransferase › Pentosyltransferases › ADP ribose transferases › ADP-ribosyltransferases, an update on function...
questionsmedicales.fr › Phénomènes génétiques › Expression des gènes › Biosynthèse des protéines › ADP-ribosyltransferases, an update on function...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléoside diphosphate ose › Adénosine diphosphate ose › Adénosine diphosphate ribose › ADP-ribosyltransferases, an update on function...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides adényliques › ADP › ADP-ribosyltransferases, an update on function...