Matthias Altmeyer

Affiliations

Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland. Electronic address: matthias.altmeyer@uzh.ch.

Publications (32)

Dealing with DNA lesions: When one cell cycle is not enough.

Current opinion in cell biology

Avec: Aleksandra Lezaja , Matthias Altmeyer

Ubiquitin Phosphorylation at Thr12 Modulates the DNA Damage Response.

Molecular cell

Avec: Franziska Walser , Monique P C Mulder , Benoît Bragantini , Sibylle Burger , Tatiana Gubser , Marco Gatti , Maria Victoria Botuyan , Alessandra Villa , Matthias Altmeyer , Dario Neri , Huib Ovaa , Georges Mer , Lorenza Penengo

FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats.

Science advances

Avec: Antonio Porro , Mohiuddin Mohiuddin , Christina Zurfluh , Vincent Spegg , Jingqi Dai , Florence Iehl , Virginie Ropars , Giulio Collotta , Keri M Fishwick , Nour L Mozaffari , Raphaël Guérois , Josef Jiricny , Matthias Altmeyer , Jean-Baptiste Charbonnier , Christopher E Pearson , Alessandro A Sartori

Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells.

Molecular cell

Avec: Florian J Groelly , Rebecca A Dagg , Michalis Petropoulos , Giacomo G Rossetti , Birbal Prasad , Andreas Panagopoulos , Teressa Paulsen , Angeliki Karamichali , Samuel E Jones , Fena Ochs , Vasilis S Dionellis , Emilia Puig Lombardi , Matthieu J Miossec , Helen Lockstone , Gaëlle Legube , Andrew N Blackford , Matthias Altmeyer , Thanos D Halazonetis , Madalena Tarsounas

RPA shields inherited DNA lesions for post-mitotic DNA synthesis.

Nature communications

Avec: Aleksandra Lezaja , Andreas Panagopoulos , Yanlin Wen , Edison Carvalho , Ralph Imhof , Matthias Altmeyer

ADP-ribosyltransferases, an update on function and nomenclature.

The FEBS journal

Avec: Bernhard Lüscher , Ivan Ahel , Matthias Altmeyer , Alan Ashworth , Peter Bai , Paul Chang , Michael Cohen , Daniela Corda , Françoise Dantzer , Matthew D Daugherty , Ted M Dawson , Valina L Dawson , Sebastian Deindl , Anthony R Fehr , Karla L H Feijs , Dmitri V Filippov , Jean-Philippe Gagné , Giovanna Grimaldi , Sebastian Guettler , Nicolas C Hoch , Michael O Hottiger , Patricia Korn , W Lee Kraus , Andreas Ladurner , Lari Lehtiö , Anthony K L Leung , Christopher J Lord , Aswin Mangerich , Ivan Matic , Jason Matthews , George-Lucian Moldovan , Joel Moss , Gioacchino Natoli , Michael L Nielsen , Mario Niepel , Friedrich Nolte , John Pascal , Bryce M Paschal , Krzysztof Pawłowski , Guy G Poirier , Susan Smith , Gyula Timinszky , Zhao-Qi Wang , José Yélamos , Xiaochun Yu , Roko Zaja , Mathias Ziegler

Biomolecular condensates at sites of DNA damage: More than just a phase.

DNA repair

Avec: Vincent Spegg , Matthias Altmeyer

Activation of homologous recombination in G1 preserves centromeric integrity.

Nature

Avec: Duygu Yilmaz , Audrey Furst , Karen Meaburn , Aleksandra Lezaja , Yanlin Wen , Matthias Altmeyer , Bernardo Reina-San-Martin , Evi Soutoglou

Genome maintenance meets mechanobiology.

Chromosoma

Avec: Vincent Spegg , Matthias Altmeyer

Phase separation properties of RPA combine high-affinity ssDNA binding with dynamic condensate functions at telomeres.

Nature structural & molecular biology

Avec: Vincent Spegg , Andreas Panagopoulos , Merula Stout , Aswini Krishnan , Giordano Reginato , Ralph Imhof , Bernd Roschitzki , Petr Cejka , Matthias Altmeyer

Dissecting the roles of MBD2 isoforms and domains in regulating NuRD complex function during cellular differentiation.

Nature communications

Avec: Nina Schmolka , Ino D Karemaker , Richard Cardoso da Silva , Davide C Recchia , Vincent Spegg , Jahnavi Bhaskaran , Michael Teske , Nathalie P de Wagenaar , Matthias Altmeyer , Tuncay Baubec

Sequential role of RAD51 paralog complexes in replication fork remodeling and restart.

Nature communications

Avec: Matteo Berti , Federico Teloni , Sofija Mijic , Sebastian Ursich , Jevgenij Fuchs , Maria Dilia Palumbieri , Jana Krietsch , Jonas A Schmid , Edwige B Garcin , Stéphanie Gon , Mauro Modesti , Matthias Altmeyer , Massimo Lopes

The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency.

Cell reports

Avec: Marco Gatti , Ralph Imhof , Qingyao Huang , Michael Baudis , Matthias Altmeyer

The Hammer and the Dance of Cell Cycle Control.

Trends in biochemical sciences

Avec: Andreas Panagopoulos , Matthias Altmeyer

RNAi Screening Uncovers a Synthetic Sick Interaction between CtIP and the BARD1 Tumor Suppressor.

Cells

Avec: Hella A Bolck , Sara Przetocka , Roger Meier , Christine von Aesch , Christina Zurfluh , Kay Hänggi , Vincent Spegg , Matthias Altmeyer , Michael Stebler , Simon F Nørrelykke , Peter Horvath , Alessandro A Sartori , Antonio Porro

Psychometric investigation of the gamification Hexad user types scale in Brazilian Portuguese.

Scientific reports

Avec: Ana Cláudia Guimarães Santos , Wilk Oliveira , Maximilian Altmeyer , Juho Hamari , Seiji Isotani

PARP1 proximity proteomics reveals interaction partners at stressed replication forks.

Nucleic acids research

Avec: Thorsten Mosler , H Irem Baymaz , Justus F Gräf , Ivan Mikicic , Georges Blattner , Edward Bartlett , Matthias Ostermaier , Rossana Piccinno , Jiwen Yang , Andrea Voigt , Marco Gatti , Stefania Pellegrino , Matthias Altmeyer , Katja Luck , Ivan Ahel , Vassilis Roukos , Petra Beli

The iron-sulfur helicase DDX11 promotes the generation of single-stranded DNA for CHK1 activation.

Life science alliance

Avec: Anna K Simon , Sandra Kummer , Sebastian Wild , Aleksandra Lezaja , Federico Teloni , Stanislaw K Jozwiakowski , Matthias Altmeyer , Kerstin Gari

The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks.

bioRxiv : the preprint server for biology

Avec: Bert van de Kooij , Fenna J van der Wal , Magdalena B Rother , Pau Creixell , Merula Stout , Wouter Wiegant , Brian A Joughin , Julia Vornberger , Marcel A T M van Vugt , Matthias Altmeyer , Michael B Yaffe , Haico van Attikum

Analysis of the PARP1, ADP-Ribosylation, and TRIP12 Triad With Markers of Patient Outcome in Human Breast Cancer.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Avec: Aswini Krishnan , Vincent Spegg , Susanne Dettwiler , Peter Schraml , Holger Moch , Konstantin Dedes , Zsuzsanna Varga , Matthias Altmeyer

The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks.

Nature communications

Avec: Bert van de Kooij , Fenna J van der Wal , Magdalena B Rother , Wouter W Wiegant , Pau Creixell , Merula Stout , Brian A Joughin , Julia Vornberger , Matthias Altmeyer , Marcel A T M van Vugt , Michael B Yaffe , Haico van Attikum

Phase separation of 53BP1 determines liquid-like behavior of DNA repair compartments.

The EMBO journal

Avec: Sinan Kilic , Aleksandra Lezaja , Marco Gatti , Eliana Bianco , Jone Michelena , Ralph Imhof , Matthias Altmeyer

Basal CHK1 activity safeguards its stability to maintain intrinsic S-phase checkpoint functions.

The Journal of cell biology

Avec: Jone Michelena , Marco Gatti , Federico Teloni , Ralph Imhof , Matthias Altmeyer

Efficient Pre-mRNA Cleavage Prevents Replication-Stress-Associated Genome Instability.

Molecular cell

Avec: Federico Teloni , Jone Michelena , Aleksandra Lezaja , Sinan Kilic , Christina Ambrosi , Shruti Menon , Jana Dobrovolna , Ralph Imhof , Pavel Janscak , Tuncay Baubec , Matthias Altmeyer

When the RAP (80) fades out, you can hear BRCA1 RING.

EMBO reports

Avec: Andreas Panagopoulos , Matthias Altmeyer

Replicated chromatin curtails 53BP1 recruitment in BRCA1-proficient and BRCA1-deficient cells.

Life science alliance

Avec: Jone Michelena , Stefania Pellegrino , Vincent Spegg , Matthias Altmeyer

Combined inhibition of Aurora-A and ATR kinase results in regression of

Nature cancer

Avec: Isabelle Roeschert , Evon Poon , Anton G Henssen , Heathcliff Dorado Garcia , Marco Gatti , Celeste Giansanti , Yann Jamin , Carsten P Ade , Peter Gallant , Christina Schülein-Völk , Petra Beli , Mark Richards , Mathias Rosenfeldt , Matthias Altmeyer , John Anderson , Angelika Eggert , Matthias Dobbelstein , Richard Bayliss , Louis Chesler , Gabriele Büchel , Martin Eilers

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks.

Nature communications

Avec: Magdalena B Rother , Stefania Pellegrino , Rebecca Smith , Marco Gatti , Cornelia Meisenberg , Wouter W Wiegant , Martijn S Luijsterburg , Ralph Imhof , Jessica A Downs , Alfred C O Vertegaal , Sébastien Huet , Matthias Altmeyer , Haico van Attikum

Mitochondrial NAD

Molecular cell

Avec: Ann-Katrin Hopp , Federico Teloni , Lavinia Bisceglie , Corentin Gondrand , Fabio Raith , Kathrin Nowak , Lukas Muskalla , Anna Howald , Patrick G A Pedrioli , Kai Johnsson , Matthias Altmeyer , Deena M Leslie Pedrioli , Michael O Hottiger

AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation.

Molecular cell

Avec: Indrajeet Ghodke , Michaela Remisova , Audrey Furst , Sinan Kilic , Bernardo Reina-San-Martin , Anna R Poetsch , Matthias Altmeyer , Evi Soutoglou

TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs.

Molecular cell

Avec: Nishita Parnandi , Veronica Rendo , Gaofeng Cui , Maria Victoria Botuyan , Michaela Remisova , Huy Nguyen , Pascal Drané , Rameen Beroukhim , Matthias Altmeyer , Georges Mer , Dipanjan Chowdhury

The CDK1-TOPBP1-PLK1 axis regulates the Bloom's syndrome helicase BLM to suppress crossover recombination in somatic cells.

Science advances

Avec: Chiara Balbo Pogliano , Ilaria Ceppi , Sara Giovannini , Vasiliki Petroulaki , Nathan Palmer , Federico Uliana , Marco Gatti , Kristina Kasaciunaite , Raimundo Freire , Ralf Seidel , Matthias Altmeyer , Petr Cejka , Joao Matos

Réseau de co-auteurs

Marco Gatti 8 collaborations

Vincent Spegg 8 collaborations

Ralph Imhof 7 collaborations

Aleksandra Lezaja 6 collaborations

Andreas Panagopoulos 5 collaborations

Federico Teloni 5 collaborations

Jone Michelena 4 collaborations

Merula Stout 3 collaborations

Stefania Pellegrino 3 collaborations

Magdalena B Rother 3 collaborations

Haico van Attikum 3 collaborations

Sinan Kilic 3 collaborations

Maria Victoria Botuyan 2 collaborations

Georges Mer 2 collaborations

Antonio Porro 2 collaborations

Christina Zurfluh 2 collaborations

Alessandro A Sartori 2 collaborations

Yanlin Wen 2 collaborations

Ivan Ahel 2 collaborations

Michael O Hottiger 2 collaborations

Audrey Furst 2 collaborations

Bernardo Reina-San-Martin 2 collaborations

Evi Soutoglou 2 collaborations

Aswini Krishnan 2 collaborations

Petr Cejka 2 collaborations

Tuncay Baubec 2 collaborations

Petra Beli 2 collaborations

Bert van de Kooij 2 collaborations

Fenna J van der Wal 2 collaborations

Pau Creixell 2 collaborations

Brian A Joughin 2 collaborations

Julia Vornberger 2 collaborations

Marcel A T M van Vugt 2 collaborations

Michael B Yaffe 2 collaborations

Wouter W Wiegant 2 collaborations

Michaela Remisova 2 collaborations

Franziska Walser 1 collaboration

Monique P C Mulder 1 collaboration

Benoît Bragantini 1 collaboration

Sibylle Burger 1 collaboration

Tatiana Gubser 1 collaboration

Alessandra Villa 1 collaboration

Dario Neri 1 collaboration

Huib Ovaa 1 collaboration

Lorenza Penengo 1 collaboration

Mohiuddin Mohiuddin 1 collaboration

Jingqi Dai 1 collaboration

Florence Iehl 1 collaboration

Virginie Ropars 1 collaboration

Giulio Collotta 1 collaboration

Keri M Fishwick 1 collaboration

Nour L Mozaffari 1 collaboration

Raphaël Guérois 1 collaboration

Josef Jiricny 1 collaboration

Jean-Baptiste Charbonnier 1 collaboration

Christopher E Pearson 1 collaboration

Florian J Groelly 1 collaboration

Rebecca A Dagg 1 collaboration

Michalis Petropoulos 1 collaboration

Giacomo G Rossetti 1 collaboration

Birbal Prasad 1 collaboration

Teressa Paulsen 1 collaboration

Angeliki Karamichali 1 collaboration

Samuel E Jones 1 collaboration

Fena Ochs 1 collaboration

Vasilis S Dionellis 1 collaboration

Emilia Puig Lombardi 1 collaboration

Matthieu J Miossec 1 collaboration

Helen Lockstone 1 collaboration

Gaëlle Legube 1 collaboration

Andrew N Blackford 1 collaboration

Thanos D Halazonetis 1 collaboration

Madalena Tarsounas 1 collaboration

Edison Carvalho 1 collaboration

Bernhard Lüscher 1 collaboration

Alan Ashworth 1 collaboration

Peter Bai 1 collaboration

Paul Chang 1 collaboration

Michael Cohen 1 collaboration

Daniela Corda 1 collaboration

Françoise Dantzer 1 collaboration

Matthew D Daugherty 1 collaboration

Ted M Dawson 1 collaboration

Valina L Dawson 1 collaboration

Sebastian Deindl 1 collaboration

Anthony R Fehr 1 collaboration

Karla L H Feijs 1 collaboration

Dmitri V Filippov 1 collaboration

Jean-Philippe Gagné 1 collaboration

Giovanna Grimaldi 1 collaboration

Sebastian Guettler 1 collaboration

Nicolas C Hoch 1 collaboration

Patricia Korn 1 collaboration

W Lee Kraus 1 collaboration

Andreas Ladurner 1 collaboration

Lari Lehtiö 1 collaboration

Anthony K L Leung 1 collaboration

Christopher J Lord 1 collaboration

Aswin Mangerich 1 collaboration

Ivan Matic 1 collaboration

Jason Matthews 1 collaboration

George-Lucian Moldovan 1 collaboration

Joel Moss 1 collaboration

Gioacchino Natoli 1 collaboration

Michael L Nielsen 1 collaboration

Mario Niepel 1 collaboration

Friedrich Nolte 1 collaboration

John Pascal 1 collaboration

Bryce M Paschal 1 collaboration

Krzysztof Pawłowski 1 collaboration

Guy G Poirier 1 collaboration

Susan Smith 1 collaboration

Gyula Timinszky 1 collaboration

Zhao-Qi Wang 1 collaboration

José Yélamos 1 collaboration

Xiaochun Yu 1 collaboration

Roko Zaja 1 collaboration

Mathias Ziegler 1 collaboration

Duygu Yilmaz 1 collaboration

Karen Meaburn 1 collaboration

Giordano Reginato 1 collaboration

Bernd Roschitzki 1 collaboration

Nina Schmolka 1 collaboration

Ino D Karemaker 1 collaboration

Richard Cardoso da Silva 1 collaboration

Davide C Recchia 1 collaboration

Jahnavi Bhaskaran 1 collaboration

Michael Teske 1 collaboration

Nathalie P de Wagenaar 1 collaboration

Matteo Berti 1 collaboration

Sofija Mijic 1 collaboration

Sebastian Ursich 1 collaboration

Jevgenij Fuchs 1 collaboration

Maria Dilia Palumbieri 1 collaboration

Jana Krietsch 1 collaboration

Jonas A Schmid 1 collaboration

Edwige B Garcin 1 collaboration

Stéphanie Gon 1 collaboration

Mauro Modesti 1 collaboration

Massimo Lopes 1 collaboration

Qingyao Huang 1 collaboration

Michael Baudis 1 collaboration

Hella A Bolck 1 collaboration

Sara Przetocka 1 collaboration

Roger Meier 1 collaboration

Christine von Aesch 1 collaboration

Kay Hänggi 1 collaboration

Michael Stebler 1 collaboration

Simon F Nørrelykke 1 collaboration

Peter Horvath 1 collaboration

Ana Cláudia Guimarães Santos 1 collaboration

Wilk Oliveira 1 collaboration

Maximilian Altmeyer 1 collaboration

Juho Hamari 1 collaboration

Seiji Isotani 1 collaboration

Thorsten Mosler 1 collaboration

H Irem Baymaz 1 collaboration

Justus F Gräf 1 collaboration

Ivan Mikicic 1 collaboration

Georges Blattner 1 collaboration

Edward Bartlett 1 collaboration

Matthias Ostermaier 1 collaboration

Rossana Piccinno 1 collaboration

Jiwen Yang 1 collaboration

Andrea Voigt 1 collaboration

Katja Luck 1 collaboration

Vassilis Roukos 1 collaboration

Anna K Simon 1 collaboration

Sandra Kummer 1 collaboration

Sebastian Wild 1 collaboration

Stanislaw K Jozwiakowski 1 collaboration

Kerstin Gari 1 collaboration

Wouter Wiegant 1 collaboration

Susanne Dettwiler 1 collaboration

Peter Schraml 1 collaboration

Holger Moch 1 collaboration

Konstantin Dedes 1 collaboration

Zsuzsanna Varga 1 collaboration

Eliana Bianco 1 collaboration

Christina Ambrosi 1 collaboration

Shruti Menon 1 collaboration

Jana Dobrovolna 1 collaboration

Pavel Janscak 1 collaboration

Isabelle Roeschert 1 collaboration

Evon Poon 1 collaboration

Anton G Henssen 1 collaboration

Heathcliff Dorado Garcia 1 collaboration

Celeste Giansanti 1 collaboration

Yann Jamin 1 collaboration

Carsten P Ade 1 collaboration

Peter Gallant 1 collaboration

Christina Schülein-Völk 1 collaboration

Mark Richards 1 collaboration

Mathias Rosenfeldt 1 collaboration

John Anderson 1 collaboration

Angelika Eggert 1 collaboration

Matthias Dobbelstein 1 collaboration

Richard Bayliss 1 collaboration

Louis Chesler 1 collaboration

Gabriele Büchel 1 collaboration

Martin Eilers 1 collaboration

Rebecca Smith 1 collaboration

Cornelia Meisenberg 1 collaboration

Martijn S Luijsterburg 1 collaboration

Jessica A Downs 1 collaboration

Alfred C O Vertegaal 1 collaboration

Sébastien Huet 1 collaboration

Ann-Katrin Hopp 1 collaboration

Lavinia Bisceglie 1 collaboration

Corentin Gondrand 1 collaboration

Fabio Raith 1 collaboration

Kathrin Nowak 1 collaboration

Lukas Muskalla 1 collaboration

Anna Howald 1 collaboration

Patrick G A Pedrioli 1 collaboration

Kai Johnsson 1 collaboration

Deena M Leslie Pedrioli 1 collaboration

Indrajeet Ghodke 1 collaboration

Anna R Poetsch 1 collaboration

Nishita Parnandi 1 collaboration

Veronica Rendo 1 collaboration

Gaofeng Cui 1 collaboration

Huy Nguyen 1 collaboration

Pascal Drané 1 collaboration

Rameen Beroukhim 1 collaboration

Dipanjan Chowdhury 1 collaboration

Chiara Balbo Pogliano 1 collaboration

Ilaria Ceppi 1 collaboration

Sara Giovannini 1 collaboration

Vasiliki Petroulaki 1 collaboration

Nathan Palmer 1 collaboration

Federico Uliana 1 collaboration

Kristina Kasaciunaite 1 collaboration

Raimundo Freire 1 collaboration

Ralf Seidel 1 collaboration

Joao Matos 1 collaboration