Impaired Priming of SARS-CoV-2-Specific Naive CD8
Adult
Aged
Aging
/ immunology
Antigens, Viral
/ immunology
CD8-Positive T-Lymphocytes
/ immunology
COVID-19
/ immunology
Cells, Cultured
Enzyme-Linked Immunospot Assay
Epitopes, T-Lymphocyte
/ immunology
Gene Expression Regulation
Healthy Volunteers
Humans
Interferon-gamma
/ genetics
Lymphocyte Activation
Middle Aged
Peptides
/ immunology
SARS-CoV-2
/ immunology
Young Adult
CD8+ T cells
SARS-CoV-2
cellular immunity
epitopes
immune aging
naive T cells
primary responses
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2021
2021
Historique:
received:
09
04
2021
accepted:
21
06
2021
entrez:
30
7
2021
pubmed:
31
7
2021
medline:
18
8
2021
Statut:
epublish
Résumé
Advanced age is associated with severe symptoms and death upon SARS-CoV-2 infection. Virus-specific CD8
Identifiants
pubmed: 34326844
doi: 10.3389/fimmu.2021.693054
pmc: PMC8315546
doi:
Substances chimiques
Antigens, Viral
0
Epitopes, T-Lymphocyte
0
Peptides
0
Interferon-gamma
82115-62-6
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
693054Informations de copyright
Copyright © 2021 Gallerani, Proietto, Dallan, Campagnaro, Pacifico, Albanese, Marzola, Marconi, Caputo, Appay, Gavioli and Nicoli.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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