Victor Appay

Affiliations

Centre d'Immunologie et des Maladies Infectieuses, Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, 75013, Paris, France. victor.appay@upmc.fr.
International Research Center of Medical Sciences, Kumamoto University, Kumamoto, 860-0811, Japan. victor.appay@upmc.fr.

Publications (25)

The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8

Scientific reports

Avec: Laura Papagno , Nozomi Kuse , Anna Lissina , Emma Gostick , David A Price , Victor Appay , Francesco Nicoli

Age differentially impacts adaptive immune responses induced by adenoviral versus mRNA vaccines against COVID-19.

Nature aging

Avec: Beatrice Dallan , Davide Proietto , Martina De Laurentis , Eleonora Gallerani , Mara Martino , Sara Ghisellini , Amedeo Zurlo , Stefano Volpato , Benedetta Govoni , Michela Borghesi , Valentina Albanese , Victor Appay , Stefano Bonnini , Sian Llewellyn-Lacey , Salvatore Pacifico , Laura Grumiro , Martina Brandolini , Simona Semprini , Vittorio Sambri , Kristin Ladell , Helen M Parry , Paul A H Moss , David A Price , Auteur inconnu , Antonella Caputo , Riccardo Gavioli , Francesco Nicoli

Cytokine profile of anti-spike CD4

iScience

Avec: Nadine Benhamouda , Anissa Besbes , Rebecca Bauer , Nesrine Mabrouk , Gauthier Gadouas , Corinne Desaint , Lucie Chevrier , Maeva Lefebvre , Anne Radenne , Marie Roelens , Béatrice Parfait , Daniela Weiskopf , Alessandro Sette , Nadège Gruel , Marie Courbebaisse , Victor Appay , Stephane Paul , Guy Gorochov , Jacques Ropers , Said Lebbah , Jean-Daniel Lelievre , Ludger Johannes , Jonathan Ulmer , David Lebeaux , Gerard Friedlander , Xavier De Lamballerie , Patrice Ravel , Marie Paule Kieny , Fréderic Batteux , Christine Durier , Odile Launay , Eric Tartour

CTL Clonotypes with Higher TCR Affinity Have Better Ability to Reduce the HIV Latent Reservoir.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Noemia S Lima , Hiroshi Takata , Szu-Han Huang , Alexander Haregot , Julie Mitchell , Stephen Blackmore , Ayanna Garland , Aaron Sy , Pearline Cartwright , Jean-Pierre Routy , Nelson L Michael , Victor Appay , R Brad Jones , Lydie Trautmann

Ageing Curtails the Diversity and Functionality of Nascent CD8

Vaccines

Avec: Davide Proietto , Beatrice Dallan , Eleonora Gallerani , Valentina Albanese , Sian Llewellyn-Lacey , David A Price , Victor Appay , Salvatore Pacifico , Antonella Caputo , Francesco Nicoli , Riccardo Gavioli

New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses.

EBioMedicine

Avec: Alice Gutjahr , Laura Papagno , Fabienne Vernejoul , Thierry Lioux , Fabienne Jospin , Blandine Chanut , Eric Perouzel , Nicolas Rochereau , Victor Appay , Bernard Verrier , Stéphane Paul

Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8

Journal of immunology (Baltimore, Md. : 1950)

Avec: Francesco Nicoli , Mariela P Cabral-Piccin , Laura Papagno , Eleonora Gallerani , Mathieu Fusaro , Victor Folcher , Marion Dubois , Emmanuel Clave , Hélène Vallet , Justin J Frere , Emma Gostick , Sian Llewellyn-Lacey , David A Price , Antoine Toubert , Loïc Dupré , Jacques Boddaert , Antonella Caputo , Riccardo Gavioli , Victor Appay

Use of a Novel Peptide Welding Technology Platform for the Development of B- and T-Cell Epitope-Based Vaccines.

Vaccines

Avec: Francesco Nicoli , Salvatore Pacifico , Eleonora Gallerani , Erika Marzola , Valentina Albanese , Valentina Finessi , Sian Llewellyn-Lacey , David A Price , Victor Appay , Peggy Marconi , Remo Guerrini , Antonella Caputo , Riccardo Gavioli

Does Inflammation Contribute to Cancer Incidence and Mortality during Aging? A Conceptual Review.

Cancers

Avec: Florent Guerville , Isabelle Bourdel-Marchasson , Julie Déchanet-Merville , Isabelle Pellegrin , Pierre Soubeyran , Victor Appay , Maël Lemoine

Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old.

EBioMedicine

Avec: Francesco Nicoli , Emmanuel Clave , Kerstin Wanke , Amrei von Braun , Vincent Bondet , Cécile Alanio , Corinne Douay , Margaux Baque , Claire Lependu , Peggy Marconi , Karin Stiasny , Franz X Heinz , Margot Muetsch , Darragh Duffy , Jacques Boddaert , Delphine Sauce , Antoine Toubert , Urs Karrer , Victor Appay

Model for predicting age-dependent safety and immunomodulatory effects of STING ligands in non-human primates.

Molecular therapy. Methods & clinical development

Avec: Shokichi Takahama , Kazuya Ishige , Takuto Nogimori , Yasuhiro Yasutomi , Victor Appay , Takuya Yamamoto

New Insights into Lymphocyte Differentiation and Aging from Telomere Length and Telomerase Activity Measurements.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Tinhinane Fali , Laura Papagno , Charles Bayard , Yanis Mouloud , Jacques Boddaert , Delphine Sauce , Victor Appay

Priming of HIV-1-specific CD8

EBioMedicine

Avec: Nozomi Kuse , Xiaoming Sun , Tomohiro Akahoshi , Anna Lissina , Takuya Yamamoto , Victor Appay , Masafumi Takiguchi

HIV-mediated immune aging in young adults infected perinatally or during childhood.

AIDS (London, England)

Avec: Solène Fastenackels , Delphine Sauce , Corinne Vigouroux , Véronique Avettand-Fènoël , Jean-Philippe Bastard , Soraya Fellahi , Laura Nailler , Elisa Arezes , Christine Rouzioux , Josiane Warszawski , Jean Paul Viard , Victor Appay , Auteur inconnu

Impaired Priming of SARS-CoV-2-Specific Naive CD8

Frontiers in immunology

Avec: Eleonora Gallerani , Davide Proietto , Beatrice Dallan , Marco Campagnaro , Salvatore Pacifico , Valentina Albanese , Erika Marzola , Peggy Marconi , Antonella Caputo , Victor Appay , Riccardo Gavioli , Francesco Nicoli

Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8

EBioMedicine

Avec: Mariela P Cabral-Piccin , Laura Papagno , Xavier Lahaye , Federico Perdomo-Celis , Stevenn Volant , Eoghann White , Valérie Monceaux , Sian Llewellyn-Lacey , Rémi Fromentin , David A Price , Nicolas Chomont , Nicolas Manel , Asier Saez-Cirion , Victor Appay

The STING ligand cGAMP potentiates the efficacy of vaccine-induced CD8+ T cells.

JCI insight

Avec: Alice Gutjahr , Laura Papagno , Francesco Nicoli , Tomohiro Kanuma , Nozomi Kuse , Mariela Pires Cabral-Piccin , Nicolas Rochereau , Emma Gostick , Thierry Lioux , Eric Perouzel , David A Price , Masafumi Takiguchi , Bernard Verrier , Takuya Yamamoto , Stéphane Paul , Victor Appay

Assessing T Lymphocyte Aging Using Telomere Length and Telomerase Activity Measurements in Low Cell Numbers.

Methods in molecular biology (Clifton, N.J.)

Avec: Tinhinane Fali , Camille K'Ros , Victor Appay , Delphine Sauce

Phenotypic and Functional Differences between Human Herpesvirus 6- and Human Cytomegalovirus-Specific T Cells.

Journal of virology

Avec: Solène Fastenackels , Charles Bayard , Martin Larsen , Philippe Magnier , Pascale Bonnafous , Nabila Seddiki , Victor Appay , Agnès Gautheret-Dejean , Delphine Sauce

Epitope length variants balance protective immune responses and viral escape in HIV-1 infection.

Cell reports

Avec: Phillip Pymm , Stefan Tenzer , Edmund Wee , Mirjana Weimershaus , Anne Burgevin , Simon Kollnberger , Jan Gerstoft , Tracy M Josephs , Kristin Ladell , James E McLaren , Victor Appay , David A Price , Lars Fugger , John I Bell , Hansjörg Schild , Peter van Endert , Maria Harkiolaki , Astrid K N Iversen

Hepatitis B surface antigen reduction is associated with hepatitis B core-specific CD8

Frontiers in immunology

Avec: Shokichi Takahama , Sachiyo Yoshio , Yuji Masuta , Hirotomo Murakami , Ryotaro Sakamori , Shun Kaneko , Takashi Honda , Miyako Murakawa , Masaya Sugiyama , Masayuki Kurosaki , Yasuhiro Asahina , Tetsuo Takehara , Victor Appay , Tatsuya Kanto , Takuya Yamamoto

CD8+ T cell priming is quantitatively but not qualitatively impaired in people with HIV-1 on antiretroviral therapy.

AIDS (London, England)

Avec: Mariela P Cabral-Piccin , Olivia Briceño , Laura Papagno , Benjamin Liouville , Eoghann White , Federico Perdomo-Celis , Gaëlle Autaa , Stevenn Volant , Sian Llewellyn-Lacey , Rémi Fromentin , Nicolas Chomont , David A Price , Asier Sáez-Cirión , Olivier Lambotte , Christine Katlama , Victor Appay

Mechanisms of systemic low-grade inflammation in HIV patients on long-term suppressive antiretroviral therapy: the inflammasome hypothesis.

AIDS (London, England)

Avec: Florent Guerville , Marine Vialemaringe , Celine Cognet , Pierre Duffau , Estibaliz Lazaro , Charles Cazanave , Fabrice Bonnet , Olivier Leleux , Rodrigue Rossignol , Benoît Pinson , Camille Tumiotto , Frederic Gabriel , Victor Appay , Julie Déchanet-Merville , Linda Wittkop , Benjamin Faustin , Isabelle Pellegrin , Auteur inconnu

Immune response to the recombinant herpes zoster vaccine in people living with HIV over 50 years of age compared to non-HIV age-/gender-matched controls (SHINGR'HIV): a multicenter, international, non-randomized clinical trial study protocol.

BMC infectious diseases

Avec: Maxime Hentzien , Fabrice Bonnet , Enos Bernasconi , Emmanuel Biver , Dominique L Braun , Aline Munting , Karoline Leuzinger , Olivier Leleux , Stefano Musardo , Virginie Prendki , Patrick Schmid , Cornelia Staehelin , Marcel Stoeckle , Carla S Walti , Linda Wittkop , Victor Appay , Arnaud M Didierlaurent , Alexandra Calmy

Clonal succession after prolonged antiretroviral therapy rejuvenates CD8

Nature immunology

Avec: Eoghann White , Laura Papagno , Assia Samri , Kenji Sugata , Boris Hejblum , Amy R Henry , Daniel C Rogan , Samuel Darko , Patricia Recordon-Pinson , Yasmine Dudoit , Sian Llewellyn-Lacey , Lisa A Chakrabarti , Florence Buseyne , Stephen A Migueles , David A Price , Marie-Aline Andreola , Yorifumi Satou , Rodolphe Thiebaut , Christine Katlama , Brigitte Autran , Daniel C Douek , Victor Appay

Réseau de co-auteurs

David A Price 10 collaborations

Laura Papagno 8 collaborations

Francesco Nicoli 8 collaborations

Sian Llewellyn-Lacey 7 collaborations

Eleonora Gallerani 5 collaborations

Antonella Caputo 5 collaborations

Riccardo Gavioli 5 collaborations

Delphine Sauce 5 collaborations

Valentina Albanese 4 collaborations

Salvatore Pacifico 4 collaborations

Takuya Yamamoto 4 collaborations

Nozomi Kuse 3 collaborations

Emma Gostick 3 collaborations

Beatrice Dallan 3 collaborations

Davide Proietto 3 collaborations

None None 3 collaborations

Mariela P Cabral-Piccin 3 collaborations

Jacques Boddaert 3 collaborations

Peggy Marconi 3 collaborations

Eoghann White 3 collaborations

Anna Lissina 2 collaborations

Kristin Ladell 2 collaborations

Alice Gutjahr 2 collaborations

Thierry Lioux 2 collaborations

Eric Perouzel 2 collaborations

Nicolas Rochereau 2 collaborations

Bernard Verrier 2 collaborations

Stéphane Paul 2 collaborations

Emmanuel Clave 2 collaborations

Antoine Toubert 2 collaborations

Erika Marzola 2 collaborations

Florent Guerville 2 collaborations

Julie Déchanet-Merville 2 collaborations

Isabelle Pellegrin 2 collaborations

Shokichi Takahama 2 collaborations

Tinhinane Fali 2 collaborations

Charles Bayard 2 collaborations

Masafumi Takiguchi 2 collaborations

Solène Fastenackels 2 collaborations

Federico Perdomo-Celis 2 collaborations

Stevenn Volant 2 collaborations

Rémi Fromentin 2 collaborations

Nicolas Chomont 2 collaborations

Christine Katlama 2 collaborations

Fabrice Bonnet 2 collaborations

Olivier Leleux 2 collaborations

Linda Wittkop 2 collaborations

Martina De Laurentis 1 collaboration

Mara Martino 1 collaboration

Sara Ghisellini 1 collaboration

Amedeo Zurlo 1 collaboration

Stefano Volpato 1 collaboration

Benedetta Govoni 1 collaboration

Michela Borghesi 1 collaboration

Stefano Bonnini 1 collaboration

Laura Grumiro 1 collaboration

Martina Brandolini 1 collaboration

Simona Semprini 1 collaboration

Vittorio Sambri 1 collaboration

Helen M Parry 1 collaboration

Paul A H Moss 1 collaboration

Nadine Benhamouda 1 collaboration

Anissa Besbes 1 collaboration

Rebecca Bauer 1 collaboration

Nesrine Mabrouk 1 collaboration

Gauthier Gadouas 1 collaboration

Corinne Desaint 1 collaboration

Lucie Chevrier 1 collaboration

Maeva Lefebvre 1 collaboration

Anne Radenne 1 collaboration

Marie Roelens 1 collaboration

Béatrice Parfait 1 collaboration

Daniela Weiskopf 1 collaboration

Alessandro Sette 1 collaboration

Nadège Gruel 1 collaboration

Marie Courbebaisse 1 collaboration

Stephane Paul 1 collaboration

Guy Gorochov 1 collaboration

Jacques Ropers 1 collaboration

Said Lebbah 1 collaboration

Jean-Daniel Lelievre 1 collaboration

Ludger Johannes 1 collaboration

Jonathan Ulmer 1 collaboration

David Lebeaux 1 collaboration

Gerard Friedlander 1 collaboration

Xavier De Lamballerie 1 collaboration

Patrice Ravel 1 collaboration

Marie Paule Kieny 1 collaboration

Fréderic Batteux 1 collaboration

Christine Durier 1 collaboration

Odile Launay 1 collaboration

Eric Tartour 1 collaboration

Noemia S Lima 1 collaboration

Hiroshi Takata 1 collaboration

Szu-Han Huang 1 collaboration

Alexander Haregot 1 collaboration

Julie Mitchell 1 collaboration

Stephen Blackmore 1 collaboration

Ayanna Garland 1 collaboration

Aaron Sy 1 collaboration

Pearline Cartwright 1 collaboration

Jean-Pierre Routy 1 collaboration

Nelson L Michael 1 collaboration

R Brad Jones 1 collaboration

Lydie Trautmann 1 collaboration

Fabienne Vernejoul 1 collaboration

Fabienne Jospin 1 collaboration

Blandine Chanut 1 collaboration

Mathieu Fusaro 1 collaboration

Victor Folcher 1 collaboration

Marion Dubois 1 collaboration

Hélène Vallet 1 collaboration

Justin J Frere 1 collaboration

Loïc Dupré 1 collaboration

Valentina Finessi 1 collaboration

Remo Guerrini 1 collaboration

Isabelle Bourdel-Marchasson 1 collaboration

Pierre Soubeyran 1 collaboration

Maël Lemoine 1 collaboration

Kerstin Wanke 1 collaboration

Amrei von Braun 1 collaboration

Vincent Bondet 1 collaboration

Cécile Alanio 1 collaboration

Corinne Douay 1 collaboration

Margaux Baque 1 collaboration

Claire Lependu 1 collaboration

Karin Stiasny 1 collaboration

Franz X Heinz 1 collaboration

Margot Muetsch 1 collaboration

Darragh Duffy 1 collaboration

Urs Karrer 1 collaboration

Kazuya Ishige 1 collaboration

Takuto Nogimori 1 collaboration

Yasuhiro Yasutomi 1 collaboration

Yanis Mouloud 1 collaboration

Xiaoming Sun 1 collaboration

Tomohiro Akahoshi 1 collaboration

Corinne Vigouroux 1 collaboration

Véronique Avettand-Fènoël 1 collaboration

Jean-Philippe Bastard 1 collaboration

Soraya Fellahi 1 collaboration

Laura Nailler 1 collaboration

Elisa Arezes 1 collaboration

Christine Rouzioux 1 collaboration

Josiane Warszawski 1 collaboration

Jean Paul Viard 1 collaboration

Marco Campagnaro 1 collaboration

Xavier Lahaye 1 collaboration

Valérie Monceaux 1 collaboration

Nicolas Manel 1 collaboration

Asier Saez-Cirion 1 collaboration

Tomohiro Kanuma 1 collaboration

Mariela Pires Cabral-Piccin 1 collaboration

Camille K'Ros 1 collaboration

Martin Larsen 1 collaboration

Philippe Magnier 1 collaboration

Pascale Bonnafous 1 collaboration

Nabila Seddiki 1 collaboration

Agnès Gautheret-Dejean 1 collaboration

Phillip Pymm 1 collaboration

Stefan Tenzer 1 collaboration

Edmund Wee 1 collaboration

Mirjana Weimershaus 1 collaboration

Anne Burgevin 1 collaboration

Simon Kollnberger 1 collaboration

Jan Gerstoft 1 collaboration

Tracy M Josephs 1 collaboration

James E McLaren 1 collaboration

Lars Fugger 1 collaboration

John I Bell 1 collaboration

Hansjörg Schild 1 collaboration

Peter van Endert 1 collaboration

Maria Harkiolaki 1 collaboration

Astrid K N Iversen 1 collaboration

Sachiyo Yoshio 1 collaboration

Yuji Masuta 1 collaboration

Hirotomo Murakami 1 collaboration

Ryotaro Sakamori 1 collaboration

Shun Kaneko 1 collaboration

Takashi Honda 1 collaboration

Miyako Murakawa 1 collaboration

Masaya Sugiyama 1 collaboration

Masayuki Kurosaki 1 collaboration

Yasuhiro Asahina 1 collaboration

Tetsuo Takehara 1 collaboration

Tatsuya Kanto 1 collaboration

Olivia Briceño 1 collaboration

Benjamin Liouville 1 collaboration

Gaëlle Autaa 1 collaboration

Asier Sáez-Cirión 1 collaboration

Olivier Lambotte 1 collaboration

Marine Vialemaringe 1 collaboration

Celine Cognet 1 collaboration

Pierre Duffau 1 collaboration

Estibaliz Lazaro 1 collaboration

Charles Cazanave 1 collaboration

Rodrigue Rossignol 1 collaboration

Benoît Pinson 1 collaboration

Camille Tumiotto 1 collaboration

Frederic Gabriel 1 collaboration

Benjamin Faustin 1 collaboration

Maxime Hentzien 1 collaboration

Enos Bernasconi 1 collaboration

Emmanuel Biver 1 collaboration

Dominique L Braun 1 collaboration

Aline Munting 1 collaboration

Karoline Leuzinger 1 collaboration

Stefano Musardo 1 collaboration

Virginie Prendki 1 collaboration

Patrick Schmid 1 collaboration

Cornelia Staehelin 1 collaboration

Marcel Stoeckle 1 collaboration

Carla S Walti 1 collaboration

Arnaud M Didierlaurent 1 collaboration

Alexandra Calmy 1 collaboration

Assia Samri 1 collaboration

Kenji Sugata 1 collaboration

Boris Hejblum 1 collaboration

Amy R Henry 1 collaboration

Daniel C Rogan 1 collaboration

Samuel Darko 1 collaboration

Patricia Recordon-Pinson 1 collaboration

Yasmine Dudoit 1 collaboration

Lisa A Chakrabarti 1 collaboration

Florence Buseyne 1 collaboration

Stephen A Migueles 1 collaboration

Marie-Aline Andreola 1 collaboration

Yorifumi Satou 1 collaboration

Rodolphe Thiebaut 1 collaboration

Brigitte Autran 1 collaboration

Daniel C Douek 1 collaboration