Lars Fugger

Affiliations

Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, Division of Clinical Neurology and Medical Research Council Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.

Publications (20)

B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2.

The Journal of experimental medicine

Avec: M Fleur du Pré , Jana Blazevski , Alisa E Dewan , Jorunn Stamnaes , Chakravarthi Kanduri , Geir Kjetil Sandve , Marie K Johannesen , Christian B Lindstad , Kathrin Hnida , Lars Fugger , Gerry Melino , Shuo-Wang Qiao , Ludvig M Sollid

The immunology of multiple sclerosis.

Nature reviews. Immunology

Avec: Kathrine E Attfield , Lise Torp Jensen , Max Kaufmann , Manuel A Friese , Lars Fugger

Characterization of T-cell receptor transgenic mice recognizing immunodominant HLA-DQ2.5-restricted gluten epitopes.

European journal of immunology

Avec: Christian B Lindstad , Shuo-Wang Qiao , Marie K Johannesen , Lars Fugger , Ludvig M Sollid , M Fleur du Pré

Mouse fetal growth restriction through parental and fetal immune gene variation and intercellular communications cascade.

Nature communications

Avec: Gurman Kaur , Caroline B M Porter , Orr Ashenberg , Jack Lee , Samantha J Riesenfeld , Matan Hofree , Maria Aggelakopoulou , Ayshwarya Subramanian , Subita Balaram Kuttikkatte , Kathrine E Attfield , Christiane A E Desel , Jessica L Davies , Hayley G Evans , Inbal Avraham-Davidi , Lan T Nguyen , Danielle A Dionne , Anna E Neumann , Lise Torp Jensen , Thomas R Barber , Elizabeth Soilleux , Mary Carrington , Gil McVean , Orit Rozenblatt-Rosen , Aviv Regev , Lars Fugger

A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity.

Nature communications

Avec: Joshua D Ooi , Jhih-Hang Jiang , Peter J Eggenhuizen , Ling L Chua , Mirjan van Timmeren , Khai L Loh , Kim M O'Sullivan , Poh Y Gan , Yong Zhong , Kirill Tsyganov , Lani R Shochet , Jessica Ryan , Coen A Stegeman , Lars Fugger , Hugh H Reid , Jamie Rossjohn , Peter Heeringa , Stephen R Holdsworth , Anton Y Peleg , A Richard Kitching

Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis.

Med (New York, N.Y.)

Avec: Max Kaufmann , Hayley Evans , Anna-Lena Schaupp , Jan Broder Engler , Gurman Kaur , Anne Willing , Nina Kursawe , Charlotte Schubert , Kathrine E Attfield , Lars Fugger , Manuel A Friese

The spatial RNA integrity number assay for in situ evaluation of transcriptome quality.

Communications biology

Avec: Linda Kvastad , Konstantin Carlberg , Ludvig Larsson , Eva Gracia Villacampa , Alexander Stuckey , Linnea Stenbeck , Annelie Mollbrink , Margherita Zamboni , Jens Peter Magnusson , Elisa Basmaci , Alia Shamikh , Gabriela Prochazka , Anna-Lena Schaupp , Åke Borg , Lars Fugger , Monica Nistér , Joakim Lundeberg

Identification of early neurodegenerative pathways in progressive multiple sclerosis.

Nature neuroscience

Avec: Max Kaufmann , Anna-Lena Schaupp , Rosa Sun , Fabian Coscia , Calliope A Dendrou , Adrian Cortes , Gurman Kaur , Hayley G Evans , Annelie Mollbrink , José Fernández Navarro , Jana K Sonner , Christina Mayer , Gabriele C DeLuca , Joakim Lundeberg , Paul M Matthews , Kathrine E Attfield , Manuel A Friese , Matthias Mann , Lars Fugger

Inflammation-related plasma and CSF biomarkers for multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Jesse Huang , Mohsen Khademi , Lars Fugger , Örjan Lindhe , Lenka Novakova , Markus Axelsson , Clas Malmeström , Clara Constantinescu , Jan Lycke , Fredrik Piehl , Tomas Olsson , Ingrid Kockum

Identifying cross-disease components of genetic risk across hospital data in the UK Biobank.

Nature genetics

Avec: Adrian Cortes , Patrick K Albers , Calliope A Dendrou , Lars Fugger , Gil McVean

Epitope length variants balance protective immune responses and viral escape in HIV-1 infection.

Cell reports

Avec: Phillip Pymm , Stefan Tenzer , Edmund Wee , Mirjana Weimershaus , Anne Burgevin , Simon Kollnberger , Jan Gerstoft , Tracy M Josephs , Kristin Ladell , James E McLaren , Victor Appay , David A Price , Lars Fugger , John I Bell , Hansjörg Schild , Peter van Endert , Maria Harkiolaki , Astrid K N Iversen

Acute Inflammatory Diseases of the Central Nervous System After SARS-CoV-2 Vaccination.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Anna G Francis , Kariem Elhadd , Valentina Camera , Monica Ferreira Dos Santos , Chiara Rocchi , Poneh Adib-Samii , Bal Athwal , Kathrine Attfield , Andrew Barritt , Matthew Craner , Leonora Fisniku , Astrid K N Iversen , Oliver Leach , Lucy Matthews , Ian Redmond , Jonathan O'Riordan , Antonio Scalfari , Radu Tanasescu , Damian Wren , Saif Huda , Maria Isabel Leite , Lars Fugger , Jacqueline Palace

Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases.

Cell

Avec: Lars Fugger , Lise Torp Jensen , Jamie Rossjohn

Recovery from COVID-19 in a B-cell-depleted multiple sclerosis patient.

Multiple sclerosis (Houndmills, Basingstoke, England)

Avec: Hannah Wurm , Kate Attfield , Astrid Kn Iversen , Ralf Gold , Lars Fugger , Aiden Haghikia

A novel neurodegenerative spectrum disorder in patients with MLKL deficiency.

Cell death & disease

Avec: Soren L Faergeman , Hayley Evans , Kathrine E Attfield , Christiane Desel , Subita Balaram Kuttikkatte , Mette Sommerlund , Lise Torp Jensen , Jorgen Frokiaer , Manuel A Friese , Paul M Matthews , Christian Luchtenborg , Britta Brügger , Annette Bang Oturai , Calliope A Dendrou , Lars Fugger

Ingested non-essential amino acids recruit brain orexin cells to suppress eating in mice.

Current biology : CB

Avec: Paulius Viskaitis , Myrtha Arnold , Celia Garau , Lise T Jensen , Lars Fugger , Daria Peleg-Raibstein , Denis Burdakov

The selection landscape and genetic legacy of ancient Eurasians.

Nature

Avec: Evan K Irving-Pease , Alba Refoyo-Martínez , William Barrie , Andrés Ingason , Alice Pearson , Anders Fischer , Karl-Göran Sjögren , Alma S Halgren , Ruairidh Macleod , Fabrice Demeter , Rasmus A Henriksen , Tharsika Vimala , Hugh McColl , Andrew H Vaughn , Leo Speidel , Aaron J Stern , Gabriele Scorrano , Abigail Ramsøe , Andrew J Schork , Anders Rosengren , Lei Zhao , Kristian Kristiansen , Astrid K N Iversen , Lars Fugger , Peter H Sudmant , Daniel J Lawson , Richard Durbin , Thorfinn Korneliussen , Thomas Werge , Morten E Allentoft , Martin Sikora , Rasmus Nielsen , Fernando Racimo , Eske Willerslev

Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations.

Nature

Avec: William Barrie , Yaoling Yang , Evan K Irving-Pease , Kathrine E Attfield , Gabriele Scorrano , Lise Torp Jensen , Angelos P Armen , Evangelos Antonios Dimopoulos , Aaron Stern , Alba Refoyo-Martinez , Alice Pearson , Abigail Ramsøe , Charleen Gaunitz , Fabrice Demeter , Marie Louise S Jørkov , Stig Bermann Møller , Bente Springborg , Lutz Klassen , Inger Marie Hyldgård , Niels Wickmann , Lasse Vinner , Thorfinn Sand Korneliussen , Morten E Allentoft , Martin Sikora , Kristian Kristiansen , Santiago Rodriguez , Rasmus Nielsen , Astrid K N Iversen , Daniel J Lawson , Lars Fugger , Eske Willerslev

Allosteric TYK2 inhibition: redefining autoimmune disease therapy beyond JAK1-3 inhibitors.

EBioMedicine

Avec: Lise Torp Jensen , Kathrine E Attfield , Marc Feldmann , Lars Fugger

Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.

Immunity

Avec: Anna H Lippert , Christopher Paluch , Meike Gaglioni , Mai T Vuong , James McColl , Edward Jenkins , Martin Fellermeyer , Joseph Clarke , Sumana Sharma , Sara Moreira da Silva , Billur Akkaya , Consuelo Anzilotti , Sara H Morgan , Claire F Jessup , Markus Körbel , Uzi Gileadi , Judith Leitner , Rachel Knox , Mami Chirifu , Jiandong Huo , Susan Yu , Nicole Ashman , Yuan Lui , Ian Wilkinson , Kathrine E Attfield , Lars Fugger , Nathan J Robertson , Christopher J Lynch , Lynne Murray , Peter Steinberger , Ana Mafalda Santos , Steven F Lee , Richard J Cornall , David Klenerman , Simon J Davis

Réseau de co-auteurs

Kathrine E Attfield 8 collaborations

Lise Torp Jensen 6 collaborations

Manuel A Friese 4 collaborations

Astrid K N Iversen 4 collaborations

Max Kaufmann 3 collaborations

Gurman Kaur 3 collaborations

Anna-Lena Schaupp 3 collaborations

Calliope A Dendrou 3 collaborations

M Fleur du Pré 2 collaborations

Marie K Johannesen 2 collaborations

Christian B Lindstad 2 collaborations

Shuo-Wang Qiao 2 collaborations

Ludvig M Sollid 2 collaborations

Subita Balaram Kuttikkatte 2 collaborations

Hayley G Evans 2 collaborations

Gil McVean 2 collaborations

Jamie Rossjohn 2 collaborations

Hayley Evans 2 collaborations

Annelie Mollbrink 2 collaborations

Joakim Lundeberg 2 collaborations

Adrian Cortes 2 collaborations

Paul M Matthews 2 collaborations

Evan K Irving-Pease 2 collaborations

William Barrie 2 collaborations

Alice Pearson 2 collaborations

Fabrice Demeter 2 collaborations

Gabriele Scorrano 2 collaborations

Abigail Ramsøe 2 collaborations

Kristian Kristiansen 2 collaborations

Daniel J Lawson 2 collaborations

Morten E Allentoft 2 collaborations

Martin Sikora 2 collaborations

Rasmus Nielsen 2 collaborations

Eske Willerslev 2 collaborations

Jana Blazevski 1 collaboration

Alisa E Dewan 1 collaboration

Jorunn Stamnaes 1 collaboration

Chakravarthi Kanduri 1 collaboration

Geir Kjetil Sandve 1 collaboration

Kathrin Hnida 1 collaboration

Gerry Melino 1 collaboration

Caroline B M Porter 1 collaboration

Orr Ashenberg 1 collaboration

Jack Lee 1 collaboration

Samantha J Riesenfeld 1 collaboration

Matan Hofree 1 collaboration

Maria Aggelakopoulou 1 collaboration

Ayshwarya Subramanian 1 collaboration

Christiane A E Desel 1 collaboration

Jessica L Davies 1 collaboration

Inbal Avraham-Davidi 1 collaboration

Lan T Nguyen 1 collaboration

Danielle A Dionne 1 collaboration

Anna E Neumann 1 collaboration

Thomas R Barber 1 collaboration

Elizabeth Soilleux 1 collaboration

Mary Carrington 1 collaboration

Orit Rozenblatt-Rosen 1 collaboration

Aviv Regev 1 collaboration

Joshua D Ooi 1 collaboration

Jhih-Hang Jiang 1 collaboration

Peter J Eggenhuizen 1 collaboration

Ling L Chua 1 collaboration

Mirjan van Timmeren 1 collaboration

Khai L Loh 1 collaboration

Kim M O'Sullivan 1 collaboration

Poh Y Gan 1 collaboration

Yong Zhong 1 collaboration

Kirill Tsyganov 1 collaboration

Lani R Shochet 1 collaboration

Jessica Ryan 1 collaboration

Coen A Stegeman 1 collaboration

Hugh H Reid 1 collaboration

Peter Heeringa 1 collaboration

Stephen R Holdsworth 1 collaboration

Anton Y Peleg 1 collaboration

A Richard Kitching 1 collaboration

Jan Broder Engler 1 collaboration

Anne Willing 1 collaboration

Nina Kursawe 1 collaboration

Charlotte Schubert 1 collaboration

Linda Kvastad 1 collaboration

Konstantin Carlberg 1 collaboration

Ludvig Larsson 1 collaboration

Eva Gracia Villacampa 1 collaboration

Alexander Stuckey 1 collaboration

Linnea Stenbeck 1 collaboration

Margherita Zamboni 1 collaboration

Jens Peter Magnusson 1 collaboration

Elisa Basmaci 1 collaboration

Alia Shamikh 1 collaboration

Gabriela Prochazka 1 collaboration

Åke Borg 1 collaboration

Monica Nistér 1 collaboration

Rosa Sun 1 collaboration

Fabian Coscia 1 collaboration

José Fernández Navarro 1 collaboration

Jana K Sonner 1 collaboration

Christina Mayer 1 collaboration

Gabriele C DeLuca 1 collaboration

Matthias Mann 1 collaboration

Jesse Huang 1 collaboration

Mohsen Khademi 1 collaboration

Örjan Lindhe 1 collaboration

Lenka Novakova 1 collaboration

Markus Axelsson 1 collaboration

Clas Malmeström 1 collaboration

Clara Constantinescu 1 collaboration

Jan Lycke 1 collaboration

Fredrik Piehl 1 collaboration

Tomas Olsson 1 collaboration

Ingrid Kockum 1 collaboration

Patrick K Albers 1 collaboration

Phillip Pymm 1 collaboration

Stefan Tenzer 1 collaboration

Edmund Wee 1 collaboration

Mirjana Weimershaus 1 collaboration

Anne Burgevin 1 collaboration

Simon Kollnberger 1 collaboration

Jan Gerstoft 1 collaboration

Tracy M Josephs 1 collaboration

Kristin Ladell 1 collaboration

James E McLaren 1 collaboration

Victor Appay 1 collaboration

David A Price 1 collaboration

John I Bell 1 collaboration

Hansjörg Schild 1 collaboration

Peter van Endert 1 collaboration

Maria Harkiolaki 1 collaboration

Anna G Francis 1 collaboration

Kariem Elhadd 1 collaboration

Valentina Camera 1 collaboration

Monica Ferreira Dos Santos 1 collaboration

Chiara Rocchi 1 collaboration

Poneh Adib-Samii 1 collaboration

Bal Athwal 1 collaboration

Kathrine Attfield 1 collaboration

Andrew Barritt 1 collaboration

Matthew Craner 1 collaboration

Leonora Fisniku 1 collaboration

Oliver Leach 1 collaboration

Lucy Matthews 1 collaboration

Ian Redmond 1 collaboration

Jonathan O'Riordan 1 collaboration

Antonio Scalfari 1 collaboration

Radu Tanasescu 1 collaboration

Damian Wren 1 collaboration

Saif Huda 1 collaboration

Maria Isabel Leite 1 collaboration

Jacqueline Palace 1 collaboration

Hannah Wurm 1 collaboration

Kate Attfield 1 collaboration

Astrid Kn Iversen 1 collaboration

Ralf Gold 1 collaboration

Aiden Haghikia 1 collaboration

Soren L Faergeman 1 collaboration

Christiane Desel 1 collaboration

Mette Sommerlund 1 collaboration

Jorgen Frokiaer 1 collaboration

Christian Luchtenborg 1 collaboration

Britta Brügger 1 collaboration

Annette Bang Oturai 1 collaboration

Paulius Viskaitis 1 collaboration

Myrtha Arnold 1 collaboration

Celia Garau 1 collaboration

Lise T Jensen 1 collaboration

Daria Peleg-Raibstein 1 collaboration

Denis Burdakov 1 collaboration

Alba Refoyo-Martínez 1 collaboration

Andrés Ingason 1 collaboration

Anders Fischer 1 collaboration

Karl-Göran Sjögren 1 collaboration

Alma S Halgren 1 collaboration

Ruairidh Macleod 1 collaboration

Rasmus A Henriksen 1 collaboration

Tharsika Vimala 1 collaboration

Hugh McColl 1 collaboration

Andrew H Vaughn 1 collaboration

Leo Speidel 1 collaboration

Aaron J Stern 1 collaboration

Andrew J Schork 1 collaboration

Anders Rosengren 1 collaboration

Lei Zhao 1 collaboration

Peter H Sudmant 1 collaboration

Richard Durbin 1 collaboration

Thorfinn Korneliussen 1 collaboration

Thomas Werge 1 collaboration

Fernando Racimo 1 collaboration

Yaoling Yang 1 collaboration

Angelos P Armen 1 collaboration

Evangelos Antonios Dimopoulos 1 collaboration

Aaron Stern 1 collaboration

Alba Refoyo-Martinez 1 collaboration

Charleen Gaunitz 1 collaboration

Marie Louise S Jørkov 1 collaboration

Stig Bermann Møller 1 collaboration

Bente Springborg 1 collaboration

Lutz Klassen 1 collaboration

Inger Marie Hyldgård 1 collaboration

Niels Wickmann 1 collaboration

Lasse Vinner 1 collaboration

Thorfinn Sand Korneliussen 1 collaboration

Santiago Rodriguez 1 collaboration

Marc Feldmann 1 collaboration

Anna H Lippert 1 collaboration

Christopher Paluch 1 collaboration

Meike Gaglioni 1 collaboration

Mai T Vuong 1 collaboration

James McColl 1 collaboration

Edward Jenkins 1 collaboration

Martin Fellermeyer 1 collaboration

Joseph Clarke 1 collaboration

Sumana Sharma 1 collaboration

Sara Moreira da Silva 1 collaboration

Billur Akkaya 1 collaboration

Consuelo Anzilotti 1 collaboration

Sara H Morgan 1 collaboration

Claire F Jessup 1 collaboration

Markus Körbel 1 collaboration

Uzi Gileadi 1 collaboration

Judith Leitner 1 collaboration

Rachel Knox 1 collaboration

Mami Chirifu 1 collaboration

Jiandong Huo 1 collaboration

Susan Yu 1 collaboration

Nicole Ashman 1 collaboration

Yuan Lui 1 collaboration

Ian Wilkinson 1 collaboration

Nathan J Robertson 1 collaboration

Christopher J Lynch 1 collaboration

Lynne Murray 1 collaboration

Peter Steinberger 1 collaboration

Ana Mafalda Santos 1 collaboration

Steven F Lee 1 collaboration

Richard J Cornall 1 collaboration

David Klenerman 1 collaboration

Simon J Davis 1 collaboration