Fredrik Piehl

Affiliations

Department of Clinical Neuroscience, Karolinska Institutet, Solna, Sweden.
Centre for Molecular Medicine, Karolinska University Hospital Solna, Solna, Sweden.

Publications (77)

The DQB1

Frontiers in neurology

Avec: Sarah Burkill , Kelsi A Smith , Pernilla Stridh , Ingrid Kockum , Jan Hillert , Hannes Lindahl , Lars Alfredsson , Tomas Olsson , Fredrik Piehl , Scott Montgomery , Shahram Bahmanyar

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

JAMA neurology

Avec: Claire Bridel , Wessel N van Wieringen , Henrik Zetterberg , Betty M Tijms , Charlotte E Teunissen , Auteur inconnu , José C Alvarez-Cermeño , Ulf Andreasson , Markus Axelsson , David C Bäckström , Ales Bartos , Maria Bjerke , Kaj Blennow , Adam Boxer , Lou Brundin , Joachim Burman , Tove Christensen , Lenká Fialová , Lars Forsgren , Jette L Frederiksen , Magnus Gisslén , Elizabeth Gray , Martin Gunnarsson , Sara Hall , Oskar Hansson , Megan K Herbert , Joel Jakobsson , Jan Jessen-Krut , Shorena Janelidze , Gudmundur Johannsson , Michael Jonsson , Ludwig Kappos , Mohsen Khademi , Michael Khalil , Jens Kuhle , Mikael Landén , Ville Leinonen , Giancarlo Logroscino , Ching-Hua Lu , Jan Lycke , Nadia K Magdalinou , Andrea Malaspina , Niklas Mattsson , Lieke H Meeter , Sanjay R Mehta , Signe Modvig , Tomas Olsson , Ross W Paterson , Josué Pérez-Santiago , Fredrik Piehl , Yolande A L Pijnenburg , Okko T Pyykkö , Oskar Ragnarsson , Julio C Rojas , Jeppe Romme Christensen , Linda Sandberg , Carole S Scherling , Jonathan M Schott , Finn T Sellebjerg , Isabella L Simone , Tobias Skillbäck , Morten Stilund , Peter Sundström , Anders Svenningsson , Rosanna Tortelli , Carla Tortorella , Alessandro Trentini , Maria Troiano , Martin R Turner , John C van Swieten , Mattias Vågberg , Marcel M Verbeek , Luisa M Villar , Pieter Jelle Visser , Anders Wallin , Andreas Weiss , Carsten Wikkelsø , Edward J Wild

Safety of Alemtuzumab and Autologous Hematopoietic Stem Cell Transplantation Compared to Noninduction Therapies for Multiple Sclerosis.

Neurology

Avec: Peter Alping , Joachim Burman , Jan Lycke , Thomas Frisell , Fredrik Piehl

International consensus on quality standards for brain health-focused care in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Avec: Jeremy Hobart , Amy Bowen , George Pepper , Harriet Crofts , Lucy Eberhard , Thomas Berger , Alexey Boyko , Cavit Boz , Helmut Butzkueven , Elisabeth Gulowsen Celius , Jelena Drulovic , José Flores , Dana Horáková , Christine Lebrun-Frénay , Ruth Ann Marrie , James Overell , Fredrik Piehl , Peter Vestergaard Rasmussen , Maria José Sá , Carmen-Adella Sîrbu , Eli Skromne , Øivind Torkildsen , Vincent van Pesch , Timothy Vollmer , Magd Zakaria , Tjalf Ziemssen , Gavin Giovannoni

Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis.

Neurology

Avec: James F Howard , Vera Bril , Ted M Burns , Renato Mantegazza , Malgorzata Bilinska , Andrzej Szczudlik , Said Beydoun , Francisco Javier Rodriguez De Rivera Garrido , Fredrik Piehl , Mariarosa Rottoli , Philip Van Damme , Tuan Vu , Amelia Evoli , Miriam Freimer , Tahseen Mozaffar , E Sally Ward , Torsten Dreier , Peter Ulrichts , Katrien Verschueren , Antonio Guglietta , Hans de Haard , Nicolas Leupin , Jan J G M Verschuuren , Auteur inconnu

Infection Risks Among Patients With Multiple Sclerosis Treated With Fingolimod, Natalizumab, Rituximab, and Injectable Therapies.

JAMA neurology

Avec: Gustavo Luna , Peter Alping , Joachim Burman , Katharina Fink , Anna Fogdell-Hahn , Martin Gunnarsson , Jan Hillert , Annette Langer-Gould , Jan Lycke , Petra Nilsson , Jonatan Salzer , Anders Svenningsson , Magnus Vrethem , Tomas Olsson , Fredrik Piehl , Thomas Frisell

Increased peripheral levels of TARC/CCL17 in first episode psychosis patients.

Schizophrenia research

Avec: Anna Malmqvist , Lilly Schwieler , Funda Orhan , Helena Fatouros-Bergman , Markus Bauer , Lena Flyckt , Simon Cervenka , Göran Engberg , Fredrik Piehl , Auteur inconnu , Sophie Erhardt

MRI-Based Manual versus Automated Corpus Callosum Volumetric Measurements in Multiple Sclerosis.

Journal of neuroimaging : official journal of the American Society of Neuroimaging

Avec: Michael Platten , Juha Martola , Katharina Fink , Russell Ouellette , Fredrik Piehl , Tobias Granberg

Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis.

Nature communications

Avec: Karl E Carlström , Keying Zhu , Ewoud Ewing , Inge E Krabbendam , Robert A Harris , Ana Mendanha Falcão , Maja Jagodic , Gonçalo Castelo-Branco , Fredrik Piehl

Diagnostic accuracy of intrathecal kappa free light chains compared with OCBs in MS.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Frida Duell , Björn Evertsson , Faiez Al Nimer , Åsa Sandin , Daniel Olsson , Tomas Olsson , Mohsen Khademi , Max Albert Hietala , Fredrik Piehl , Magnus Hansson

Validation of Rapid Magnetic Resonance Myelin Imaging in Multiple Sclerosis.

Annals of neurology

Avec: Russell Ouellette , Gabriel Mangeat , Ildiko Polyak , Marcel Warntjes , Yngve Forslin , Åsa Bergendal , Michael Plattén , Martin Uppman , Constantina Andrada Treaba , Julien Cohen-Adad , Fredrik Piehl , Maria Kristoffersen Wiberg , Sten Fredrikson , Caterina Mainero , Tobias Granberg

Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain Injury.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Edward J Needham , Oda Stoevesandt , Eric P Thelin , Henrik Zetterberg , Elisa R Zanier , Faiez Al Nimer , Nicholas J Ashton , Joanne G Outtrim , Virginia F J Newcombe , Hani S Mousa , Joel Simrén , Kaj Blennow , Zhihui Yang , Peter J Hutchinson , Fredrik Piehl , Adel E Helmy , Mike J Taussig , Kevin K W Wang , Joanne L Jones , David K Menon , Alasdair J Coles

Elevated endogenous GDNF induces altered dopamine signalling in mice and correlates with clinical severity in schizophrenia.

Molecular psychiatry

Avec: Kärt Mätlik , Daniel R Garton , Ana R Montaño-Rodríguez , Soophie Olfat , Feride Eren , Laoise Casserly , Anastasios Damdimopoulos , Anne Panhelainen , L Lauriina Porokuokka , Jaakko J Kopra , Giorgio Turconi , Nadine Schweizer , Erika Bereczki , Fredrik Piehl , Göran Engberg , Simon Cervenka , T Petteri Piepponen , Fu-Ping Zhang , Petra Sipilä , Johan Jakobsson , Carl M Sellgren , Sophie Erhardt , Jaan-Olle Andressoo

Screening for pathogenic neuronal autoantibodies in serum and CSF of patients with first-episode psychosis.

Translational psychiatry

Avec: Jakob Theorell , Melanie Ramberger , Ruby Harrison , Victor Mgbachi , Leslie Jacobson , Patrick Waters , Sophie Erhardt , Carl M Sellgren , Simon Cervenka , Fredrik Piehl , Sarosh R Irani

Hospital-treated infections in early- and mid-life and risk of Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis: A nationwide nested case-control study in Sweden.

PLoS medicine

Avec: Jiangwei Sun , Jonas F Ludvigsson , Caroline Ingre , Fredrik Piehl , Karin Wirdefeldt , Ulrika Zagai , Weimin Ye , Fang Fang

A highly challenging balance training intervention for people with multiple sclerosis: a feasibility trial.

Pilot and feasibility studies

Avec: A Wallin , E Franzén , U Ekman , F Piehl , S Johansson

Granulocyte activation markers in cerebrospinal fluid differentiate acute neuromyelitis spectrum disorder from multiple sclerosis.

Journal of neurology, neurosurgery, and psychiatry

Avec: David Leppert , Mitsuru Watanabe , Sabine Schaedelin , Fredrik Piehl , Roberto Furlan , Matteo Gastaldi , Jeremy Lambert , Björn Evertsson , Katharina Fink , Takuya Matsushita , Katsuhisa Masaki , Noriko Isobe , Jun-Ichi Kira , Pascal Benkert , Aleksandra Maceski , Eline Willemse , Johanna Oechtering , Annette Orleth , Stephanie Meier , Jens Kuhle

Safety and efficacy of rituximab versus dimethyl fumarate in patients with relapsing-remitting multiple sclerosis or clinically isolated syndrome in Sweden: a rater-blinded, phase 3, randomised controlled trial.

The Lancet. Neurology

Avec: Anders Svenningsson , Thomas Frisell , Joachim Burman , Jonatan Salzer , Katharina Fink , Susanna Hallberg , Joakim Hambraeus , Markus Axelsson , Faiez Al Nimer , Peter Sundström , Martin Gunnarsson , Rune Johansson , Johan Mellergård , Igal Rosenstein , Ahmad Ayad , Irina Sjöblom , Anette Risedal , Pierre de Flon , Eric Gilland , Jonas Lindeberg , Fadi Shawket , Fredrik Piehl , Jan Lycke

Systemic Capillary Leak Syndrome With Cerebral Involvement in a

Neurology. Genetics

Avec: Stefan Sennfält , Oskar Aspegren , Martin Engvall , Tobias Granberg , Fredrik Piehl

Haematopoietic stem cell transplantation for treatment of relapsing-remitting multiple sclerosis in Sweden: an observational cohort study.

Journal of neurology, neurosurgery, and psychiatry

Avec: Thomas Silfverberg , Christina Zjukovskaja , Per Ljungman , Adjmal Nahimi , Erik Ahlstrand , Arta Dreimane , Sigrun Einarsdottir , Jan Fagius , Ellen Iacobaeus , Hans Hägglund , Niclas Lange , Stig Lenhoff , Jan Lycke , Johan Mellergård , Fredrik Piehl , Anders Svenningsson , Andreas Tolf , Honar Cherif , Kristina Carlson , Joachim Burman

A Genetic Risk Variant for Multiple Sclerosis Severity is Associated with Brain Atrophy.

Annals of neurology

Avec: Christiane Gasperi , Tun Wiltgen , Julian McGinnis , Stefano Cerri , Thomas Moridi , Russell Ouellette , Albert Pukaj , Cuici Voon , Cemsel Bafligil , Markus Lauerer , Till F M Andlauer , Friederike Held , Lilian Aly , Klementy Shchetynsky , Pernilla Stridh , Adil Harroud , Benedikt Wiestler , Jan S Kirschke , Claus Zimmer , Aris Baras , Fredrik Piehl , Achim Berthele , Tobias Granberg , Ingrid Kockum , Bernhard Hemmer , Mark Mühlau

Development and multi-center validation of a fully automated digital immunoassay for neurofilament light chain: toward a clinical blood test for neuronal injury.

Clinical chemistry and laboratory medicine

Avec: David Wilson , Dandan Chan , Lei Chang , Robert Mathis , Inge Verberk , Xavier Montalban , Manuel Comabella , Nicolas Fissolo , Bibi Bielekova , Ruturaj Masvekar , Tanuja Chitnis , Tjalf Ziemssen , Katja Akgün , Kaj Blennow , Henrik Zetterberg , Wolfgang Brück , Gavin Giovannoni , Sharmilee Gnanapavan , Stefan Bittner , Frauke Zipp , Giancarlo Comi , Roberto Furlan , Sylvain Lehmann , Simon Thebault , Mark Freedman , Amit Bar-Or , Marty Kramer , Markus Otto , Steffen Halbgebauer , Kevin Hrusovsky , Tatiana Plavina , Michael Khalil , Fredrik Piehl , Heinz Wiendl , Ludwig Kappos , Aleksandra Maceski , Eline Willemse , David Leppert , Charlotte Teunissen , Jens Kuhle

Neurofilaments as biomarkers in neurological disorders - towards clinical application.

Nature reviews. Neurology

Avec: Michael Khalil , Charlotte E Teunissen , Sylvain Lehmann , Markus Otto , Fredrik Piehl , Tjalf Ziemssen , Stefan Bittner , Maria Pia Sormani , Thomas Gattringer , Samir Abu-Rumeileh , Simon Thebault , Ahmed Abdelhak , Ari Green , Pascal Benkert , Ludwig Kappos , Manuel Comabella , Hayrettin Tumani , Mark S Freedman , Axel Petzold , Kaj Blennow , Henrik Zetterberg , David Leppert , Jens Kuhle

Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study.

The Lancet. Neurology

Avec: Anna He , Bernd Merkel , James William L Brown , Lana Zhovits Ryerson , Ilya Kister , Charles B Malpas , Sifat Sharmin , Dana Horakova , Eva Kubala Havrdova , Tim Spelman , Guillermo Izquierdo , Sara Eichau , Maria Trojano , Alessandra Lugaresi , Raymond Hupperts , Patrizia Sola , Diana Ferraro , Jan Lycke , Francois Grand'Maison , Alexandre Prat , Marc Girard , Pierre Duquette , Catherine Larochelle , Anders Svenningsson , Thor Petersen , Pierre Grammond , Franco Granella , Vincent Van Pesch , Roberto Bergamaschi , Christopher McGuigan , Alasdair Coles , Jan Hillert , Fredrik Piehl , Helmut Butzkueven , Tomas Kalincik , Auteur inconnu

Inflammation-related plasma and CSF biomarkers for multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Jesse Huang , Mohsen Khademi , Lars Fugger , Örjan Lindhe , Lenka Novakova , Markus Axelsson , Clas Malmeström , Clara Constantinescu , Jan Lycke , Fredrik Piehl , Tomas Olsson , Ingrid Kockum

CSF levels of synaptosomal-associated protein 25 and synaptotagmin-1 in first-episode psychosis subjects.

IBRO reports

Avec: Chengai Xu , Carl M Sellgren , Helena Fatouros-Bergman , Fredrik Piehl , Kaj Blennow , Henrik Zetterberg , Ann Brinkmalm , Alexander Frizell Santillo , Sofia Lundgren , Simon Cervenka , Göran Engberg , Sophie Erhardt , Auteur inconnu

Successful combined treatment with thymectomy, rituximab and tocilizumab for severe thymoma-associated multi autoimmune syndrome.

Journal of neuroimmunology

Avec: Olafur Sveinsson , Fredrik Piehl , Oskar Aspegren , Max Albert Hietala

Rituximab treatment for multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Avec: Benjamin V Ineichen , Thomas Moridi , Tobias Granberg , Fredrik Piehl

GM-CSF and CXCR4 define a T helper cell signature in multiple sclerosis.

Nature medicine

Avec: Edoardo Galli , Felix J Hartmann , Bettina Schreiner , Florian Ingelfinger , Eirini Arvaniti , Martin Diebold , Dunja Mrdjen , Franziska van der Meer , Carsten Krieg , Faiez Al Nimer , Nicholas Sanderson , Christine Stadelmann , Mohsen Khademi , Fredrik Piehl , Manfred Claassen , Tobias Derfuss , Tomas Olsson , Burkhard Becher

Assessing the Preanalytical Variability of Plasma and Cerebrospinal Fluid Processing and Its Effects on Inflammation-Related Protein Biomarkers.

Molecular & cellular proteomics : MCP

Avec: Jesse Huang , Mohsen Khademi , Örjan Lindhe , Gunn Jönsson , Fredrik Piehl , Tomas Olsson , Ingrid Kockum

Confounding effect of blood volume and body mass index on blood neurofilament light chain levels.

Annals of clinical and translational neurology

Avec: Ali Manouchehrinia , Fredrik Piehl , Jan Hillert , Jens Kuhle , Lars Alfredsson , Tomas Olsson , Ingrid Kockum

Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain injury.

Scientific reports

Avec: Karolina Minta , Gunnar Brinkmalm , Faiez Al Nimer , Eric P Thelin , Fredrik Piehl , Mats Tullberg , Anna Jeppsson , Erik Portelius , Henrik Zetterberg , Kaj Blennow , Ulf Andreasson

Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA (

Frontiers in neurology

Avec: Sonja Hochmeister , Shahin Aeinehband , Charles Dorris , Rasmus Berglund , Michaela T Haindl , Vid Velikic , Sven A Gustafsson , Tomas Olsson , Fredrik Piehl , Maja Jagodic , Manuel Zeitelhofer , Milena Z Adzemovic

Deep Learning Corpus Callosum Segmentation as a Neurodegenerative Marker in Multiple Sclerosis.

Journal of neuroimaging : official journal of the American Society of Neuroimaging

Avec: Michael Platten , Irene Brusini , Olle Andersson , Russell Ouellette , Fredrik Piehl , Chunliang Wang , Tobias Granberg

Correlation between leukocyte phenotypes and prognosis of amyotrophic lateral sclerosis.

eLife

Avec: Can Cui , Caroline Ingre , Li Yin , Xia Li , John Andersson , Christina Seitz , Nicolas Ruffin , Yudi Pawitan , Fredrik Piehl , Fang Fang

Patient-Reported Symptom Severity in a Nationwide Myasthenia Gravis Cohort: Cross-sectional Analysis of the Swedish GEMG Study.

Neurology

Avec: Malin Petersson , Amalia Feresiadou , Daniel Jons , Andreea Ilinca , Fredrik Lundin , Rune Johansson , Anna Budzianowska , Anna-Karin Roos , Viktor Kågström , Martin Gunnarsson , Peter Sundström , Fredrik Piehl , Susanna Brauner

High-intensity resistance training in people with multiple sclerosis experiencing fatigue: A randomised controlled trial.

Multiple sclerosis and related disorders

Avec: S Englund , F Piehl , M Kierkegaard

Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia.

Nature communications

Avec: Jessica Gracias , Funda Orhan , Elin Hörbeck , Jessica Holmén-Larsson , Neda Khanlarkani , Susmita Malwade , Sravan K Goparaju , Lilly Schwieler , İlknur Ş Demirel , Ting Fu , Helena Fatourus-Bergman , Aurimantas Pelanis , Carleton P Goold , Anneli Goulding , Kristina Annerbrink , Anniella Isgren , Timea Sparding , Martin Schalling , Viviana A Carcamo Yañez , Jens C Göpfert , Johanna Nilsson , Ann Brinkmalm , Kaj Blennow , Henrik Zetterberg , Göran Engberg , Fredrik Piehl , Steven D Sheridan , Roy H Perlis , Simon Cervenka , Sophie Erhardt , Mikael Landen , Carl M Sellgren

Structural magnetic resonance imaging findings and histopathological correlations in motor neuron diseases-A systematic review and meta-analysis.

Frontiers in neurology

Avec: Charlotte Zejlon , Dominik Nakhostin , Sebastian Winklhofer , Athina Pangalu , Zsolt Kulcsar , Sebastian Lewandowski , Johannes Finnsson , Fredrik Piehl , Caroline Ingre , Tobias Granberg , Benjamin Victor Ineichen

Sustained Low Relapse Rate With Highly Variable B-Cell Repopulation Dynamics With Extended Rituximab Dosing Intervals in Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Chiara Starvaggi Cucuzza , Elisa Longinetti , Nicolas Ruffin , Björn Evertsson , Ingrid Kockum , Maja Jagodic , Faiez Al Nimer , Thomas Frisell , Fredrik Piehl

Impact of previous treatment history and B-cell depletion treatment duration on infection risk in relapsing-remitting multiple sclerosis: a nationwide cohort study.

Journal of neurology, neurosurgery, and psychiatry

Avec: Suvi Virtanen , Fredrik Piehl , Thomas Frisell

Dilated Virchow-Robin spaces are a marker for arterial disease in multiple sclerosis.

EBioMedicine

Avec: Benjamin V Ineichen , Carmen Cananau , Michael Plattén , Russell Ouellette , Thomas Moridi , Katrin B M Frauenknecht , Serhat V Okar , Zsolt Kulcsar , Ingrid Kockum , Fredrik Piehl , Daniel S Reich , Tobias Granberg

Trajectories of cognitive processing speed and physical disability over 11 years following initiation of a first multiple sclerosis disease-modulating therapy.

Journal of neurology, neurosurgery, and psychiatry

Avec: Elisa Longinetti , Simon Englund , Joachim Burman , Katharina Fink , Anna Fogdell-Hahn , Martin Gunnarsson , Jan Hillert , Annette Magdalene Langer-Gould , Jan Lycke , Petra Nilsson , Jonatan Salzer , Anders Svenningsson , Johan Mellergård , Tomas Olsson , Fredrik Piehl , Thomas Frisell

Improving the efficiency of clinical trials in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)

Avec: Ruth Ann Marrie , Maria Pia Sormani , Sean Apap Mangion , Francesca Bovis , Winson Y Cheung , Gary R Cutter , Peter Feys , Michael D Hill , Marcus Werner Koch , Morgan McCreary , Ellen M Mowry , Jay Jh Park , Fredrik Piehl , Amber Salter , Jeremy Chataway

The impact of hybrid immunity on immune responses after SARS-CoV-2 vaccination in persons with multiple sclerosis treated with disease-modifying therapies.

European journal of neurology

Avec: Monika Rabenstein , Olivia G Thomas , Giorgia Carlin , Mohsen Khademi , Klara Asplund Högelin , Clas Malmeström , Markus Axelsson , Anne Frandsen Brandt , Guro Gafvelin , Hans Grönlund , Ingrid Kockum , Fredrik Piehl , Jan Lycke , Tomas Olsson , Tara Hessa

Cerebrospinal fluid levels of neuroinflammatory biomarkers are increased in athletes with persistent post-concussive symptoms following sports-related concussion.

Journal of neuroinflammation

Avec: Anna Gard , Fredrik Vedung , Fredrik Piehl , Mohsen Khademi , Maria Portonova Wernersson , Ia Rorsman , Yelverton Tegner , Hélène Pessah-Rasmussen , Karsten Ruscher , Niklas Marklund

Disrupted-in-schizophrenia 1 protein aggregates in cerebrospinal fluid are elevated in patients with first-episode psychosis.

Psychiatry and clinical neurosciences

Avec: Marlene Pils , Julia Rutsch , Feride Eren , Göran Engberg , Fredrik Piehl , Simon Cervenka , Carl Sellgren , Svenja Troßbach , Dieter Willbold , Sophie Erhardt , Oliver Bannach , Carsten Korth

Neuroimaging findings in preclinical amyotrophic lateral sclerosis models-How well do they mimic the clinical phenotype? A systematic review.

Frontiers in veterinary science

Avec: Amelia Elaine Cannon , Wolfgang Emanuel Zürrer , Charlotte Zejlon , Zsolt Kulcsar , Sebastian Lewandowski , Fredrik Piehl , Tobias Granberg , Benjamin Victor Ineichen

Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis.

Nature communications

Avec: Julia Åkesson , Sara Hojjati , Sandra Hellberg , Johanna Raffetseder , Mohsen Khademi , Robert Rynkowski , Ingrid Kockum , Claudio Altafini , Zelmina Lubovac-Pilav , Johan Mellergård , Maria C Jenmalm , Fredrik Piehl , Tomas Olsson , Jan Ernerudh , Mika Gustafsson

Neurodegenerative biomarkers outperform neuroinflammatory biomarkers in amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis & frontotemporal degeneration

Avec: Ulf Kläppe , Stefan Sennfält , Anikó Lovik , Anja Finn , Ulrika Bofaisal , Henrik Zetterberg , Kaj Blennow , Fredrik Piehl , Ivan Kmezic , Rayomand Press , Kristin Samuelsson , Anna Månberg , Fang Fang , Caroline Ingre

Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis.

JAMA neurology

Avec: Stephanie Meier , Eline A J Willemse , Sabine Schaedelin , Johanna Oechtering , Johannes Lorscheider , Lester Melie-Garcia , Alessandro Cagol , Muhamed Barakovic , Riccardo Galbusera , Suvitha Subramaniam , Christian Barro , Ahmed Abdelhak , Simon Thebault , Lutz Achtnichts , Patrice Lalive , Stefanie Müller , Caroline Pot , Anke Salmen , Giulio Disanto , Chiara Zecca , Marcus D'Souza , Annette Orleth , Michael Khalil , Arabella Buchmann , Renaud Du Pasquier , Özgür Yaldizli , Tobias Derfuss , Klaus Berger , Marco Hermesdorf , Heinz Wiendl , Fredrik Piehl , Marco Battaglini , Urs Fischer , Ludwig Kappos , Claudio Gobbi , Cristina Granziera , Claire Bridel , David Leppert , Aleksandra Maleska Maceski , Pascal Benkert , Jens Kuhle

Economic and societal burden of myasthenia gravis in Denmark, Finland, and Sweden: A population-based registry study.

European journal of neurology

Avec: Fredrik Piehl , John Vissing , Juha Mehtälä , Fredrik Berggren , Ingrid Lindberg-Schager , Didier Pitsi , Evangelos Tsitlakidis , Aino Vesikansa , Riina-Minna Väänänen , Tero Ylisaukko-Oja , Sari Atula

Comparison Between Rituximab Treatment for New-Onset Generalized Myasthenia Gravis and Refractory Generalized Myasthenia Gravis.

JAMA neurology

Avec: Susanna Brauner , Ann Eriksson-Dufva , Max Albert Hietala , Thomas Frisell , Rayomand Press , Fredrik Piehl

Characterization of More Selective Central Nervous System Nrf2-Activating Novel Vinyl Sulfoximine Compounds Compared to Dimethyl Fumarate.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Avec: Karl E Carlström , Praveen K Chinthakindi , Belén Espinosa , Faiez Al Nimer , Elias S J Arnér , Per I Arvidsson , Fredrik Piehl , Katarina Johansson

Enlarged perivascular spaces in multiple sclerosis on magnetic resonance imaging: a systematic review and meta-analysis.

Journal of neurology

Avec: Tobias Granberg , Thomas Moridi , Judith S Brand , Susanne Neumann , Martin Hlavica , Fredrik Piehl , Benjamin V Ineichen

Cancer Risk for Fingolimod, Natalizumab, and Rituximab in Multiple Sclerosis Patients.

Annals of neurology

Avec: Peter Alping , Johan Askling , Joachim Burman , Katharina Fink , Anna Fogdell-Hahn , Martin Gunnarsson , Jan Hillert , Annette Langer-Gould , Jan Lycke , Petra Nilsson , Jonatan Salzer , Anders Svenningsson , Magnus Vrethem , Tomas Olsson , Fredrik Piehl , Thomas Frisell

Neurological manifestations of coronavirus infections - a systematic review.

Annals of clinical and translational neurology

Avec: Jesper Almqvist , Tobias Granberg , Antonios Tzortzakakis , Stefanos Klironomos , Evangelia Kollia , Claes Öhberg , Roland Martin , Fredrik Piehl , Russell Ouellette , Benjamin V Ineichen

Non-infectious comorbidity in patients with multiple sclerosis: A national cohort study in Sweden.

Multiple sclerosis journal - experimental, translational and clinical

Avec: Anna Castelo-Branco , Flaminia Chiesa , Camilla E Bengtsson , Sally Lee , Neil N Minton , Steve Niemcryk , Anders Lindholm , Mats Rosenlund , Fredrik Piehl , Scott Montgomery

Rituximab, MS, and pregnancy.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Jessica B Smith , Kerstin Hellwig , Katharina Fink , Deirdre J Lyell , Fredrik Piehl , Annette Langer-Gould

Epilepsy in systemic lupus erythematosus: prevalence and risk factors.

European journal of neurology

Avec: L Hopia , M Andersson , E Svenungsson , M Khademi , F Piehl , T Tomson

Incidence of osmotic demyelination syndrome in Sweden: A nationwide study.

Acta neurologica Scandinavica

Avec: Hildur Aegisdottir , Charith Cooray , Karin Wirdefeldt , Fredrik Piehl , Olafur Sveinsson

Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes.

Nature communications

Avec: Karl E Carlström , Ewoud Ewing , Mathias Granqvist , Alexandra Gyllenberg , Shahin Aeinehband , Sara Lind Enoksson , Antonio Checa , Tejaswi V S Badam , Jesse Huang , David Gomez-Cabrero , Mika Gustafsson , Faiez Al Nimer , Craig E Wheelock , Ingrid Kockum , Tomas Olsson , Maja Jagodic , Fredrik Piehl

Comparative effectiveness of dimethyl fumarate as the initial and secondary treatment for MS.

Multiple sclerosis (Houndmills, Basingstoke, England)

Avec: Mathias Granqvist , Joachim Burman , Martin Gunnarsson , Jan Lycke , Petra Nilsson , Tomas Olsson , Peter Sundström , Anders Svenningsson , Magnus Vrethem , Thomas Frisell , Fredrik Piehl

Dynamics of extracellular matrix proteins in cerebrospinal fluid and serum and their relation to clinical outcome in human traumatic brain injury.

Clinical chemistry and laboratory medicine

Avec: Karolina Minta , Nicholas C Cullen , Faiez Al Nimer , Eric P Thelin , Fredrik Piehl , Marcus Clarin , Mats Tullberg , Anna Jeppsson , Erik Portelius , Henrik Zetterberg , Kaj Blennow , Ulf Andreasson

miR-31 regulates energy metabolism and is suppressed in T cells from patients with Sjögren's syndrome.

European journal of immunology

Avec: Alina Johansson , William A Nyberg , Maria Sjöstrand , Noah Moruzzi , Petra Bergman , Mohsen Khademi , Magnus Andersson , Fredrik Piehl , Per-Olof Berggren , Ruxandra Covacu , Maja Jagodic , Alexander Espinosa

Association of Infectious Mononucleosis in Childhood and Adolescence With Risk for a Subsequent Multiple Sclerosis Diagnosis Among Siblings.

JAMA network open

Avec: Yin Xu , Ayako Hiyoshi , Kelsi A Smith , Fredrik Piehl , Tomas Olsson , Katja Fall , Scott Montgomery

Current and emerging disease-modulatory therapies and treatment targets for multiple sclerosis.

Journal of internal medicine

Avec: F Piehl

Cerebrospinal fluid brevican and neurocan fragment patterns in human traumatic brain injury.

Clinica chimica acta; international journal of clinical chemistry

Avec: Karolina Minta , Gunnar Brinkmalm , Eric P Thelin , Faiez Al Nimer , Fredrik Piehl , Mats Tullberg , Anna Jeppsson , Erik Portelius , Henrik Zetterberg , Kaj Blennow , Ulf Andreasson

Disease activity in pregnancy and postpartum in women with MS who suspended rituximab and natalizumab.

Neurology(R) neuroimmunology & neuroinflammation

Avec: Neda Razaz , Fredrik Piehl , Thomas Frisell , Annette M Langer-Gould , Kyla A McKay , Katharina Fink

Hospital-diagnosed infections before age 20 and risk of a subsequent multiple sclerosis diagnosis.

Brain : a journal of neurology

Avec: Yin Xu , Kelsi A Smith , Ayako Hiyoshi , Fredrik Piehl , Tomas Olsson , Scott Montgomery

Quantification of Plasma Kynurenine Metabolites Following One Bout of Sprint Interval Exercise.

International journal of tryptophan research : IJTR

Avec: Ada Trepci , Sophie Imbeault , Victoria L Wyckelsma , Håkan Westerblad , Sigurd Hermansson , Daniel C Andersson , Fredrik Piehl , Tomas Venckunas , Marius Brazaitis , Sigitas Kamandulis , Lena Brundin , Sophie Erhardt , Lilly Schwieler

Development of humoral and cellular immunological memory against SARS-CoV-2 despite B cell depleting treatment in multiple sclerosis.

iScience

Avec: Klara Asplund Högelin , Nicolas Ruffin , Elisa Pin , Anna Månberg , Sophia Hober , Guro Gafvelin , Hans Grönlund , Peter Nilsson , Mohsen Khademi , Tomas Olsson , Fredrik Piehl , Faiez Al Nimer

The Karolinska NeuroCOVID study protocol: Neurocognitive impairment, biomarkers and advanced imaging in critical care survivors.

Acta anaesthesiologica Scandinavica

Avec: David W Nelson , Tobias Granberg , Pia Andersen , Elias Jokhadar , Jessica Kåhlin , Anna Granström , Helena Hallinder , Anna Schening , Charlotta Thunborg , Håkan Walles , Göran Hagman , Roya Shams-Latifi , Jimmy Yu , Sven Petersson , Antonios Tzortzakakis , Nicholas Levak , Malin Aspö , Fredrik Piehl , Henrik Zetterberg , Miia Kivipelto , Lars I Eriksson

Efficacy and Safety of Rituximab for New-Onset Generalized Myasthenia Gravis: The RINOMAX Randomized Clinical Trial.

JAMA neurology

Avec: Fredrik Piehl , Ann Eriksson-Dufva , Anna Budzianowska , Amalia Feresiadou , William Hansson , Max Albert Hietala , Irene Håkansson , Rune Johansson , Daniel Jons , Ivan Kmezic , Christopher Lindberg , Jonas Lindh , Fredrik Lundin , Ingela Nygren , Anna Rostedt Punga , Rayomand Press , Kristin Samuelsson , Peter Sundström , Oskar Wickberg , Susanna Brauner , Thomas Frisell

Demographic and disease-related factors impact on cerebrospinal fluid neurofilament light chain levels in multiple sclerosis.

Brain and behavior

Avec: Kamila Zondra Revendova , Chiara Starvaggi Cucuzza , Ali Manouchehrinia , Mohsen Khademi , Michal Bar , David Leppert , Elisabeth Sandberg , Russell Ouellette , Tobias Granberg , Fredrik Piehl

Multiple sclerosis, disease-modifying drugs and risk for adverse perinatal and pregnancy outcomes: Results from a population-based cohort study.

Multiple sclerosis (Houndmills, Basingstoke, England)

Avec: Katharina Fink , Agnes Gorczyca , Peter Alping , Simon Englund , Susan Farmand , Annette M Langer-Gould , Fredrik Piehl , Kyla McKay , Thomas Frisell , Neda Razaz

Infections among individuals with multiple sclerosis, Alzheimer's disease and Parkinson's disease.

Brain communications

Avec: Yihan Hu , Kejia Hu , Huan Song , Yudi Pawitan , Fredrik Piehl , Fang Fang

Réseau de co-auteurs

Tomas Olsson 18 collaborations

Tobias Granberg 13 collaborations

Thomas Frisell 12 collaborations

Henrik Zetterberg 11 collaborations

Mohsen Khademi 11 collaborations

Jan Lycke 11 collaborations

Faiez Al Nimer 11 collaborations

Ingrid Kockum 10 collaborations

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None None 5 collaborations

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Kelsi A Smith 3 collaborations

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