Phillip Pymm

Affiliations

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.
Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC, Australia.

Publications (17)

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.

Nature communications

Avec: Shoeib Moradi , Sanda Stankovic , Geraldine M O'Connor , Phillip Pymm , Bruce J MacLachlan , Camilla Faoro , Christelle Retière , Lucy C Sullivan , Philippa M Saunders , Jacqueline Widjaja , Shea Cox-Livingstone , Jamie Rossjohn , Andrew G Brooks , Julian P Vivian

Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain.

Cell reports

Avec: Adam K Wheatley , Phillip Pymm , Robyn Esterbauer , Melanie H Dietrich , Wen Shi Lee , Damien Drew , Hannah G Kelly , Li-Jin Chan , Francesca L Mordant , Katrina A Black , Amy Adair , Hyon-Xhi Tan , Jennifer A Juno , Kathleen M Wragg , Thakshila Amarasena , Ester Lopez , Kevin J Selva , Ebene R Haycroft , James P Cooney , Hariprasad Venugopal , Li Lynn Tan , Matthew T O Neill , Cody C Allison , Deborah Cromer , Miles P Davenport , Richard A Bowen , Amy W Chung , Marc Pellegrini , Mark T Liddament , Alisa Glukhova , Kanta Subbarao , Stephen J Kent , Wai-Hong Tham

Simultaneous evaluation of antibodies that inhibit SARS-CoV-2 variants via multiplex assay.

JCI insight

Avec: Ester Lopez , Ebene R Haycroft , Amy Adair , Francesca L Mordant , Matthew T O'Neill , Phillip Pymm , Samuel J Redmond , Wen Shi Lee , Nicholas A Gherardin , Adam K Wheatley , Jennifer A Juno , Kevin J Selva , Samantha K Davis , Samantha L Grimley , Leigh Harty , Damian Fj Purcell , Kanta Subbarao , Dale I Godfrey , Stephen J Kent , Wai-Hong Tham , Amy W Chung

Corrigendum: Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2.

Frontiers in immunology

Avec: Bruce D Wines , Liriye Kurtovic , Halina M Trist , Sandra Esparon , Ester Lopez , Klasina Chappin , Li-Jin Chan , Francesca L Mordant , Wen Shi Lee , Nicholas A Gherardin , Sheila K Patel , Gemma E Hartley , Phillip Pymm , James P Cooney , James G Beeson , Dale I Godfrey , Louise M Burrell , Menno C van Zelm , Adam K Wheatley , Amy W Chung , Wai-Hong Tham , Kanta Subbarao , Stephen J Kent , P Mark Hogarth

The Structural Basis for Recognition of Human Leukocyte Antigen Class I Molecules by the Pan-HLA Antibody W6/32.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Phillip Pymm , Philippa M Saunders , Sushma Anand , Bruce J MacLachlan , Camilla Faoro , Corinne Hitchen , Jamie Rossjohn , Andrew G Brooks , Julian P Vivian

Heterologous SARS-CoV-2 IgA neutralising antibody responses in convalescent plasma.

Clinical & translational immunology

Avec: Samantha K Davis , Kevin John Selva , Ester Lopez , Ebene R Haycroft , Wen Shi Lee , Adam K Wheatley , Jennifer A Juno , Amy Adair , Phillip Pymm , Samuel J Redmond , Nicholas A Gherardin , Dale I Godfrey , Wai-Hong Tham , Stephen J Kent , Amy W Chung

A placental model of SARS-CoV-2 infection reveals ACE2-dependent susceptibility and differentiation impairment in syncytiotrophoblasts.

Nature cell biology

Avec: J Chen , J A Neil , J P Tan , R Rudraraju , M Mohenska , Y B Y Sun , E Walters , N G Bediaga , G Sun , Y Zhou , Y Li , D Drew , P Pymm , W H Tham , F J Rossello , G Nie , X Liu , K Subbarao , J M Polo

Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19.

Nature medicine

Avec: Jennifer A Juno , Hyon-Xhi Tan , Wen Shi Lee , Arnold Reynaldi , Hannah G Kelly , Kathleen Wragg , Robyn Esterbauer , Helen E Kent , C Jane Batten , Francesca L Mordant , Nicholas A Gherardin , Phillip Pymm , Melanie H Dietrich , Nichollas E Scott , Wai-Hong Tham , Dale I Godfrey , Kanta Subbarao , Miles P Davenport , Stephen J Kent , Adam K Wheatley

Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Phillip Pymm , Amy Adair , Li-Jin Chan , James P Cooney , Francesca L Mordant , Cody C Allison , Ester Lopez , Ebene R Haycroft , Matthew T O'Neill , Li Lynn Tan , Melanie H Dietrich , Damien Drew , Marcel Doerflinger , Michael A Dengler , Nichollas E Scott , Adam K Wheatley , Nicholas A Gherardin , Hariprasad Venugopal , Deborah Cromer , Miles P Davenport , Raelene Pickering , Dale I Godfrey , Damian F J Purcell , Stephen J Kent , Amy W Chung , Kanta Subbarao , Marc Pellegrini , Alisa Glukhova , Wai-Hong Tham

Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p.

The Biochemical journal

Avec: Melanie H Dietrich , Li-Jin Chan , Amy Adair , Sravya Keremane , Phillip Pymm , Alvin W Lo , Yi-Chun Cao , Wai-Hong Tham

Antibody Fc-binding profiles and ACE2 affinity to SARS-CoV-2 RBD variants.

Medical microbiology and immunology

Avec: Ebene R Haycroft , Samantha K Davis , Pradhipa Ramanathan , Ester Lopez , Ruth A Purcell , Li Lynn Tan , Phillip Pymm , Bruce D Wines , P Mark Hogarth , Adam K Wheatley , Jennifer A Juno , Samuel J Redmond , Nicholas A Gherardin , Dale I Godfrey , Wai-Hong Tham , Kevin John Selva , Stephen J Kent , Amy W Chung

Human coronavirus OC43 nanobody neutralizes virus and protects mice from infection.

Journal of virology

Avec: Amy Adair , Li Lynn Tan , Jackson Feng , Jason Girkin , Nathan Bryant , Mingyang Wang , Francesca Mordant , Li-Jin Chan , Nathan W Bartlett , Kanta Subbarao , Phillip Pymm , Wai-Hong Tham

The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Philippa M Saunders , Bruce J MacLachlan , Phillip Pymm , Patricia T Illing , Yuanchen Deng , Shu Cheng Wong , Clare V L Oates , Anthony W Purcell , Jamie Rossjohn , Julian P Vivian , Andrew G Brooks

Epitope length variants balance protective immune responses and viral escape in HIV-1 infection.

Cell reports

Avec: Phillip Pymm , Stefan Tenzer , Edmund Wee , Mirjana Weimershaus , Anne Burgevin , Simon Kollnberger , Jan Gerstoft , Tracy M Josephs , Kristin Ladell , James E McLaren , Victor Appay , David A Price , Lars Fugger , John I Bell , Hansjörg Schild , Peter van Endert , Maria Harkiolaki , Astrid K N Iversen

Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2.

iScience

Avec: Phillip Pymm , Samuel J Redmond , Olan Dolezal , Francesca Mordant , Ester Lopez , James P Cooney , Kathryn C Davidson , Ebene R Haycroft , Chee Wah Tan , Rebecca Seneviratna , Samantha L Grimley , Damian F J Purcell , Stephen J Kent , Adam K Wheatley , Lin-Fa Wang , Andrew Leis , Alisa Glukhova , Marc Pellegrini , Amy W Chung , Kanta Subbarao , Adam P Uldrich , Wai-Hong Tham , Dale I Godfrey , Nicholas A Gherardin

Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2.

Frontiers in immunology

Prediction of KIR3DL1/Human Leukocyte Antigen binding.

bioRxiv : the preprint server for biology

Avec: Martin Maiers , Yoram Louzoun , Philip Pymm , Julian P Vivian , Jamie Rossjohn , Andrew G Brooks , Philippa M Saunders

Réseau de co-auteurs

Wai-Hong Tham 11 collaborations

Adam K Wheatley 9 collaborations

Stephen J Kent 9 collaborations

Ester Lopez 8 collaborations

Amy W Chung 8 collaborations

Kanta Subbarao 8 collaborations

Nicholas A Gherardin 8 collaborations

Dale I Godfrey 8 collaborations

Wen Shi Lee 6 collaborations

Li-Jin Chan 6 collaborations

Francesca L Mordant 6 collaborations

Amy Adair 6 collaborations

Ebene R Haycroft 6 collaborations

Jennifer A Juno 5 collaborations

James P Cooney 5 collaborations

Philippa M Saunders 4 collaborations

Jamie Rossjohn 4 collaborations

Andrew G Brooks 4 collaborations

Julian P Vivian 4 collaborations

Melanie H Dietrich 4 collaborations

Li Lynn Tan 4 collaborations

Samuel J Redmond 4 collaborations

Bruce J MacLachlan 3 collaborations

Miles P Davenport 3 collaborations

Marc Pellegrini 3 collaborations

Alisa Glukhova 3 collaborations

Samantha K Davis 3 collaborations

Bruce D Wines 3 collaborations

P Mark Hogarth 3 collaborations

Camilla Faoro 2 collaborations

Robyn Esterbauer 2 collaborations

Damien Drew 2 collaborations

Hannah G Kelly 2 collaborations

Hyon-Xhi Tan 2 collaborations

Kevin J Selva 2 collaborations

Hariprasad Venugopal 2 collaborations

Cody C Allison 2 collaborations

Deborah Cromer 2 collaborations

Matthew T O'Neill 2 collaborations

Samantha L Grimley 2 collaborations

Liriye Kurtovic 2 collaborations

Halina M Trist 2 collaborations

Sandra Esparon 2 collaborations

Klasina Chappin 2 collaborations

Sheila K Patel 2 collaborations

Gemma E Hartley 2 collaborations

James G Beeson 2 collaborations

Louise M Burrell 2 collaborations

Menno C van Zelm 2 collaborations

Kevin John Selva 2 collaborations

Nichollas E Scott 2 collaborations

Damian F J Purcell 2 collaborations

Francesca Mordant 2 collaborations

Shoeib Moradi 1 collaboration

Sanda Stankovic 1 collaboration

Geraldine M O'Connor 1 collaboration

Christelle Retière 1 collaboration

Lucy C Sullivan 1 collaboration

Jacqueline Widjaja 1 collaboration

Shea Cox-Livingstone 1 collaboration

Katrina A Black 1 collaboration

Kathleen M Wragg 1 collaboration

Thakshila Amarasena 1 collaboration

Matthew T O Neill 1 collaboration

Richard A Bowen 1 collaboration

Mark T Liddament 1 collaboration

Leigh Harty 1 collaboration

Damian Fj Purcell 1 collaboration

Sushma Anand 1 collaboration

Corinne Hitchen 1 collaboration

J Chen 1 collaboration

J A Neil 1 collaboration

J P Tan 1 collaboration

R Rudraraju 1 collaboration

M Mohenska 1 collaboration

Y B Y Sun 1 collaboration

E Walters 1 collaboration

N G Bediaga 1 collaboration

G Sun 1 collaboration

Y Zhou 1 collaboration

Y Li 1 collaboration

D Drew 1 collaboration

P Pymm 1 collaboration

W H Tham 1 collaboration

F J Rossello 1 collaboration

G Nie 1 collaboration

X Liu 1 collaboration

K Subbarao 1 collaboration

J M Polo 1 collaboration

Arnold Reynaldi 1 collaboration

Kathleen Wragg 1 collaboration

Helen E Kent 1 collaboration

C Jane Batten 1 collaboration

Marcel Doerflinger 1 collaboration

Michael A Dengler 1 collaboration

Raelene Pickering 1 collaboration

Sravya Keremane 1 collaboration

Alvin W Lo 1 collaboration

Yi-Chun Cao 1 collaboration

Pradhipa Ramanathan 1 collaboration

Ruth A Purcell 1 collaboration

Jackson Feng 1 collaboration

Jason Girkin 1 collaboration

Nathan Bryant 1 collaboration

Mingyang Wang 1 collaboration

Nathan W Bartlett 1 collaboration

Patricia T Illing 1 collaboration

Yuanchen Deng 1 collaboration

Shu Cheng Wong 1 collaboration

Clare V L Oates 1 collaboration

Anthony W Purcell 1 collaboration

Stefan Tenzer 1 collaboration

Edmund Wee 1 collaboration

Mirjana Weimershaus 1 collaboration

Anne Burgevin 1 collaboration

Simon Kollnberger 1 collaboration

Jan Gerstoft 1 collaboration

Tracy M Josephs 1 collaboration

Kristin Ladell 1 collaboration

James E McLaren 1 collaboration

Victor Appay 1 collaboration

David A Price 1 collaboration

Lars Fugger 1 collaboration

John I Bell 1 collaboration

Hansjörg Schild 1 collaboration

Peter van Endert 1 collaboration

Maria Harkiolaki 1 collaboration

Astrid K N Iversen 1 collaboration

Olan Dolezal 1 collaboration

Kathryn C Davidson 1 collaboration

Chee Wah Tan 1 collaboration

Rebecca Seneviratna 1 collaboration

Lin-Fa Wang 1 collaboration

Andrew Leis 1 collaboration

Adam P Uldrich 1 collaboration

Martin Maiers 1 collaboration

Yoram Louzoun 1 collaboration

Philip Pymm 1 collaboration