Characterization of Temperature-Dependent Kinetics of Oculocutaneous Albinism-Causing Mutants of Tyrosinase.
L-DOPA binding
OCA1B mutations
Van’t Hoff analysis
decreased dopachrome in mutant variants
human recombinant tyrosinases
temperature-dependent kinetics
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
21 Jul 2021
21 Jul 2021
Historique:
received:
04
06
2021
revised:
12
07
2021
accepted:
16
07
2021
entrez:
7
8
2021
pubmed:
8
8
2021
medline:
17
8
2021
Statut:
epublish
Résumé
Human tyrosinase (Tyr) is a glycoenzyme that catalyzes the first and rate-limiting step in melanin production, and its gene (
Identifiants
pubmed: 34360537
pii: ijms22157771
doi: 10.3390/ijms22157771
pmc: PMC8346126
pii:
doi:
Substances chimiques
Monophenol Monooxygenase
EC 1.14.18.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Foundation for the National Institutes of Health
ID : ZIA EY000476-10
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