Mediated electrochemistry for redox-based biological targeting: entangling sensing and actuation for maximizing information transfer.
Journal
Current opinion in biotechnology
ISSN: 1879-0429
Titre abrégé: Curr Opin Biotechnol
Pays: England
ID NLM: 9100492
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
received:
19
04
2021
revised:
02
07
2021
accepted:
14
07
2021
pubmed:
8
8
2021
medline:
12
11
2021
entrez:
7
8
2021
Statut:
ppublish
Résumé
Biology and electronics are both expert at receiving, analyzing, and responding to information, yet they use entirely different information processing paradigms. Biology processes information using networks that are intrinsically molecular while electronics process information through circuits that control the flow of electrons. There is great interest in coupling the molecular logic of biology with the electronic logic of technology, and we suggest that redox (reduction-oxidation) is a uniquely suited modality for interfacing biology with electronics. Specifically, redox is a native biological modality and is accessible to electronics through electrodes. We summarize recent advances in mediated electrochemistry to direct information transfer into biological systems intentionally altering function, exposing it for more advanced interpretation, which can dramatically expand the biotechnological toolbox.
Identifiants
pubmed: 34364305
pii: S0958-1669(21)00129-4
doi: 10.1016/j.copbio.2021.07.017
pii:
doi:
Types de publication
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
137-144Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.