Total Syntheses of Aturanosides A and B.

Angiogenesis Inhibitors / chemical synthesis Anthraquinones / chemical synthesis Glycosides / chemical synthesis Glycosylation Molecular Structure

Journal

Organic letters
ISSN: 1523-7052
Titre abrégé: Org Lett
Pays: United States
ID NLM: 100890393

Informations de publication

Date de publication:
03 09 2021
Historique:
pubmed: 13 8 2021
medline: 28 1 2022
entrez: 12 8 2021
Statut: ppublish

Résumé

Total syntheses of aturanosides A and B, two antiangiogenic anthraquinone glycosides, have been achieved in an expeditious manner, highlighting anthraquinone synthesis, phenol glycosylation, α-d-glucosaminoside installation, and judicious use of protecting groups.

Identifiants

DOI: 10.1021/acs.orglett.1c02244 PMID: 34383489
pubmed: 34383489
doi: 10.1021/acs.orglett.1c02244
doi:

Substances chimiques

Angiogenesis Inhibitors 0
Anthraquinones 0
Glycosides 0
aturanoside A 0
aturanoside B 0
9,10-anthraquinone 030MS0JBDO

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

6680-6684

Auteurs

Yingjie Wang (Y)

State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.

Biao Yu (B)

State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
School of Chemistry and Materials Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, 1 Sub-lane Xiangshan, Hangzhou 310024, China.
ORCID: 0000-0002-3607-578X

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Inhibiteurs de l'angiogenèse › Total Syntheses of Aturanosides A and B.
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Anthracènes › Anthraquinones › Total Syntheses of Aturanosides A and B.
questionsmedicales.fr › Glucides › Hétérosides › Total Syntheses of Aturanosides A and B.
questionsmedicales.fr › Métabolisme › Métabolisme glucidique › Glycosylation › Total Syntheses of Aturanosides A and B.
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Total Syntheses of Aturanosides A and B.